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Epitomics Product References

Latest publications using antibodies from Epitomics



342 antibodies referenced in 689 publications
Name / Catalog# Title Journal Author App
ABCG1
1945-1
The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteumReproduction 139 (2010) 163-176Bogan RL, Hennebold JDWB
ABCG1
1945-1
TNF-α decreases ABCA1 expression and attenuates HDL cholesterol efflux in the human intestinal cell line Caco-2J Lipid Res 51 (2010) 1407-1415Field FJ, Watt K, Mathur SN
Acetyl CoA Carboxylase 1 (ACC1)
1768-1
Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectinFASEB J 23 (2009) 241-258Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, et alWB
Acetyl CoA Carboxylase 1 (ACC1)
1768-1
Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanismBiochem Biophys Res Commun 388 (2009) 311-316Ota S, Horigome K, Ishii T, et alWB
Acetyl CoA Carboxylase 1 (ACC1)
1771-1
Mechanism of Homocysteine-Induced Rac1/ NADPH Oxidase Activation in Mesangial Cells: Role of Guanine Nucleotide Exchange Factor Vav2Cell Physiol Biochem 20 (2007) 909-918Yi F, Chen QZ, Jin S, et alWB
Actin
1844-1
Recruitment of vimentin to the cell surface by β3 integrin and plectin mediates adhesion strengthJ. Cell Sci.122 (2009) 1390 - 1400Bhattacharya R, Gonzalez AM, DeBiase PJ, et al
Actin
1844-1
The important role of actinin-like protein (AcnA) in cytokinesis and apical dominance of hyphal cells in Aspergillus nidulansMicrobiology 155 (2009) 2714 - 2725Wang JJ, Hu HQ, Wang S, et al
Actin
1844-1
Recruitment of vimentin to the cell surface by β3 integrin and plectin mediates adhesion strengthJ Cell Sci 122 (2009) 1390-1400Bhattacharya R, Gonzalez AM, Debiase PJ, et al
AIF
1020-1
Nuclear Translocation of Endonuclease G and Apoptosis-Inducing Factor during Acetaminophen-Induced Liver Cell InjuryToxicologial Sciences 94 (2006) 217–225Bajt ML, Cover C, Lemasters JJ, et alIHC
AIF
1020-1
MicroRNA145 Targets BNIP3 and Suppresses Prostate Cancer ProgressionCancer Res 70 (2010) 2728-2738Chen X, Gong J, Zeng H, et al
AIF
1020-1
Critical Role of Calpain I in Mitochondrial Release of Apoptosis-Inducing Factor in Ischemic Neuronal InjuryThe Journal of Neuroscience 27 (2007) 9278 –9293Cao GD, Xing J, Xiao X, et alWB
AIF
1020-1
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell deathPNAS 103 (2006) 18314 –18319Yu SW, Andrabi SA, Wang HM, et alICC
AIF
1020-1
c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicityToxicol Appl Pharmacol 246 (2010) 8-17Saito C, Lemasters JJ, Jaeschke HWB
AIF
1020-1
Loss of Apoptosis-Inducing Factor Results in Cell-Type-Specific Neurogenesis DefectsThe Journal of Neuroscience 28 (2008) 4938–4948Ishimura R, Martin GR and Ackerman SLIHC
AIF
1020-1
Mammalian Ste20-like protein kinase 3 induces a caspase-independent apoptotic pathwayInt J Biochem Cell Biol 42 (2010) 98-105Lin CY, Wu HY, Wang PL, et alWB
AIF
1020-1
The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cellsAsian J Androl 12 (2010) 527-534Huang R, Chen XQ, Huang Y, et alWB
AIF
1020-1
Mitochondrial Bax Translocation Accelerates DNA Fragmentation and Cell Necrosis in a Murine Model of Acetaminophen HepatotoxicityJPET 324 (2008) 8–14Bajt ML, Farhood A, Lemasters JJ, et alWB
AIF
1020-1
Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanismsNeurobiol Dis 37 (2010) 711-722Shen H, Hu X, Liu C, et alWB
Akt1 Phospho (pS473)
2118-1
Activation of Phosphatidylinositol 3-Kinase by Membrane Localization of p110α Predisposes Mammary Glands to Neoplastic TransformationCancer Res 68 (2008) 9643-9653Renner O, Blanco-Aparicio C, Grassow M, et alIHC
Akt1 Phospho (pS473)
2118-1
A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer CellsMol Cancer Ther 9 (2010) 2934-2942Kunoh T, Noda T, Koseki K, et al
Akt1 Phospho (pS473)
2118-1
Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse ModelsPLoS One 5 (2010) e9305Blanco-Aparicio C, Cañamero M, Cecilia Y, et alIHC
Akt1 Phospho (pS473)
2118-1
Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cellsOncogene 29 (2010) 2712-2723Pommier AJ, Alves G, Viennois E, et alICC
Akt1 Phospho (pT308)
2214-1
PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac DevelopmentMol Cell Biol 30 (2010) 3711-3721Feng Q, Di R, Tao F, et al
Aldh1A1
2293-1
Increased levels of active c-Src distinguish invasive from in situ lobular lesionsBreast Cancer Res 11 (2009) R45Zou D, Yoon HS, Anjomshoaa A, et alIHC
ALDH7A1 antibody
S3071
Integrative Genomics Identifies Molecular Alterations that Challenge the Linear Model of Melanoma ProgressionCancer Res 71 (2011) 2561-2571Rose AE, Poliseno L, Wang J, et al
Alpha-1 Catenin
2028-1
α– E-catenin binds to dynamitin and regulates dynactin-mediated intracellular trafficJ. Cell Biol. 183 (2008) 989 - 997Lien WH, Gelfand VI, Vasioukhin VIP
Alpha-Actin (Smooth Muscle)
1184-1
Immunohistochemical Localization of Six Galectin Subtypes in the Mouse Digestive TractJ. Histochem. Cytochem. 57 (2009) 41 - 50Nio-Kobayashi J, Takahashi-Iwanaga H, Iwanaga TIHC
Alpha-Actin (Smooth Muscle)
1184-1
Cellular Plasticity of Inflammatory Myeloid Cells in the Peritoneal Foreign Body ResponseAm J Pathol 176 (2010) 369-380Mooney JE, Rolfe BE, Osborne GW, et alICC
Alpha-Actin (Smooth Muscle)
1184-1
Oleate Induces a Myofibroblast-Like Phenotype in Mesangial CellsArterioscler Thromb Vasc Biol 28 (2008) 541-547Mishra R, Simonson MSICC
Alpha-Actin (Smooth Muscle)
1184-1
The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblastsFree Radic Biol Med 49 (2010) 88-95Lang YD, Hung CL, Wu TY, et alWB
Alpha-Actin (Smooth Muscle)
1184-1
Presence of a-smooth muscle actin-positive endothelial cells in the luminal surface of adult aortaBiochemical and Biophysical Research Communications 380 (2009) 620–626Azuma K, Ichimura K, Mita T, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
A novel cell-adhesive scaffold material for delivering keratinocytes reduces granulation tissue in dermal woundsWound Rep Reg 17 (2009) 127–135Masuda R, Mochizuki M, Hozumi K, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exerciseJ Physiol 588(2010) 3971-3982Fleenor BS, Marshall KD, Durrant JR, et al
Alpha-Actin (Smooth Muscle)
1184-1
Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1 -/- miceAm J Physiol Lung Cell Mol Physiol 294 (2008) L865 - L873Maniatis NA, Shinin V, Schraufnagel DE, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
Ultraviolet B radiation regulates cysteine-rich protein 1 in human keratinocytesPhotodermatol Photoimmunol Photomed 26 (2010) 70-77Latonen L, Järvinen PM, Suomela S, et alICC
Alpha-Actin (Smooth Muscle)
1184-1
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell nicheNat Med. 15 (2009) 701-706Ootani A, Li X, Sangiorgi E, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
Towards a pragmatic strategy for regenerating infarcted myocardium with glandular stem cellsAnnals of Anatomy - Anatomischer Anzeiger 191 (2009) 51-61Maass A, Kajahn J, Guerleyik E, et alICC
Alpha-Actin (Smooth Muscle)
1184-1
Maternal Exposure to Particulate Matter Increases Postnatal Ozone-induced Airway Hyperreactivity in Juvenile MiceAm J Respir Crit Care Med 180 (2009) 1218-1226Auten RL, Potts EN, Mason SN, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
AMP-activated Protein Kinase Inhibits Transforming Growth Factor- -induced Smad3-dependent Transcription and Myofibroblast TransdifferentiationThe Journal of Biological Chemistry 283 (2008) 10461-10469Mishra R, Cool BL, Laderoute KR, et alELISA
Alpha-Actin (Smooth Muscle)
1184-1
Cellular Plasticity of Inflammatory Myeloid Cells in the Peritoneal Foreign Body ResponseAm. J. Pathol. 176 (2010) 369-380Mooney JE, Rolfe BE, Osborne GW, et al
Alpha-Actin (Smooth Muscle)
1184-1
The Synergistic Inhibition of Atherogenesis in ApoE-/- Mice Between Pravastatin and the sPLA2 Inhibitor Varespladib (A-002)J Lipid Res. 50 (2009) 623-629Shaposhnik Z, Wang XP, Trias J, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
Vascular Endothelial Growth Factor Secreted by Activated Stroma Enhances Angiogenesis and Hormone-Independent Growth of Estrogen Receptor–Positive Breast CancerCancer Res 70 (2010) 2655-2664Pinto MP, Badtke MM, Dudevoir ML, et al
Alpha-Actin (Smooth Muscle)
1184-1
T-cadherin suppresses angiogenesis in vivo by inhibiting migration of endothelial cellsAngiogenesis 10 (2007) 183–195Rubina K, Kalinina N, Potekhina AICC
Alpha-Actin (Smooth Muscle)
1184-1
Human Renal Cancer Cells Express a Novel Membrane-Bound Interleukin-15 that Induces, in Response to the Soluble Interleukin-15 Receptor α Chain, Epithelial-to-Mesenchymal TransitionCancer Res 69 (2009) 1561-1569Khawam K, Giron-Michel J, Gu Y, et alWB
Alpha-Actin (Smooth Muscle)
1184-1
Generation of functional gut-like organ from mouse induced pluripotent stem cellsBiochem Biophys Res Commun 391 (2010) 38-42Ueda T, Yamada T, Hokuto D, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
The Synthetic Peroxisome Proliferator-Activated Receptor-γ Agonist Ciglitazone Attenuates Neuroinflammation and Accelerates Encapsulation in Bacterial Brain AbscessesThe Journal of Immunology 180 (2008) 5004–5016Kielian T, Syed MM, Liu SL, et alICC
Alpha-Actin (Smooth Muscle)
1184-1
Single-Dose Gamma-Irradiation Induces Up-Regulation of Chemokine Gene Expression and Recruitment of Granulocytes into the Portal Area but Not into Other Regions of Rat Hepatic TissueAm J Pathol 176 (2010) 1801-1815Malik IA, Moriconi F, Sheikh N, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
Microvascular maturity elicited in tissue treated with cytokine-loaded hyaluronan-based hydrogelsBiomaterials 29 (2008) 2336-2347Hosack LW, Firpo MA, Scott JA, et alIHC
Alpha-Actin (Smooth Muscle)
1184-1
Thy-1 is an in vivo and in vitro marker of liver myofibroblastsCell Tissue Res 329 (2007) 503–514Dudas J, Mansuroglu T, Batusic D, et alIHC
Alpha-Synuclein
2016-1
Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implicationsBiochem Biophys Res Commun 387 (2009) 149-52Qing H, Wong W, McGeer EG, et alWB
Alpha-Synuclein Phospho (pS129)
2014-1
Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implicationsBiochem Biophys Res Commun 387 (2009) 149-52Qing H, Wong W, McGeer EG, et alWB
Alpha-Synuclein Phospho (pS129)
2014-1
Improved Immunodetection of Endogenous α-SynucleinPLoS OneLee BR, Kamitani TWB
Alpha-Tubulin
1878-1
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteinsPNAS 105 (2008) 19318 - 19323Wang XL, Su B, Siedlaka SL, et alWB, ICC
Alpha-Tubulin
1878-1
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's DiseaseJ. Neurosci. 29 (2009) 9090 - 9103Wang XL, Su B, Lee HG, et al
Alpha-Tubulin
1878-1
Aggregates Assembled From Overexpression of Wild-Type α-Synuclein are not Toxic to Human Neuronal CellsJ Neuropathol Exp Neurol 67 (2008) 1084-1096Ko LW, Ko HHC, Lin WL, et alWB
Alpha-Tubulin
2871-1
Influence of Ser/Pro-rich domain and kinase domain of double cortin-like protein kinase on microtubule-binding activityJ Biochem 149 (2011) 619-627Nagamine T, Shimomura S, Sueyoshi N, et al
Alpha-Tubulin
1878-1
Ethanol enhances tau accumulation in neuroblastoma cells that inducibly express tauNeuroscience Letters 443 (2008) 67-71Gendron TF, McCartney S, Causevic E, et alWB
AMPK alpha 1
1596-1
Activation of Wnt/β-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle CellsPLoS One 4 (2009) e8509Abiola M, Favier M, Christodoulou-Vafeiadou E, et alWB
AMPK beta 1
1604-1
Impaired Skeletal Muscle β-Adrenergic Activation and Lipolysis Are Associated with Whole-Body Insulin Resistance in Rats Bred for Low Intrinsic Exercise CapacityEndocrinology 150 (2009) 4883 - 4891Lessard SJ, Rivas DA, Chen ZP, et alWB
AMPK beta 1
1604-1
AMPK 1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin ResistanceJ Biol Chem 285 (2010) 115-122Dzamko N, van Denderen BJ, Hevener AL, et alWB
AMPK beta 1
1604-1
Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immuno-electron MicroscopyJ. Histochem. Cytochem. 57 (2009) 963 - 971Bendayan M, Londono I, Kemp BE, et alWB
AMPK beta 1
1604-1
Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immunoelectron MicroscopyJ. Histochem. Cytochem. 57 (2009) 963 - 971Bendayan M, Londono I, Kemp BE, et al
AMPK beta 1
1604-1
Hypothalamic CaMKK2 Contributes to the Regulation of Energy BalanceCell Metab 7 (2008) 377-388Anderson KA, Ribar TJ, Lin F, et alWB
AMPK gamma-1 (C-term)
1592-1
Hypothalamic CaMKK2 Contributes to the Regulation of Energy BalanceCell Metab 7 (2008) 377-388Anderson KA, Ribar TJ, Lin F, et alWB
Androgen Receptor
1852-1
Androgen Receptor Levels and Associationwith PIK3CA Mutations and Prognosis in Breast CancerClin Cancer Res. 15 (2009) 2472-2478Gonzalez-Angulo AM, Stemke-Hale K, Palla SL, et alRPPA
Apaf-1
1038-1
The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemiasCell Death Differ 15 (2008) 1712-1722Kamitsuji Y, Kuroda J, Kimura S, et alWB
Apolipoprotein E
1930-1
A Proteomic Approach for the Diagnosis of Bacterial MeningitisPLoS One 5 (2010) e10079Jesse S, Steinacker P, Lehnert S, et alWB
APP
1565-1
A Single Tyrosine Residue in the Amyloid Precursor Protein Intracellular Domain Is Essential for Developmental FunctionJ Biol Chem 286 (2011) 8717-8721Barbagallo AP, Wang Z, Zheng H, et al
APP
1565-1
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APPProc Natl Acad Sci U S A 107 (2010) 17362-17367Li H, Wang B, Wang Z, et al
APP
1565-1
Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central SynaptogenesisJ. Neurosci. 29 (2009) 10788 - 10801Wang ZL, Wang BP, Yang L, et al
ARF1
1635-1
p24A, a Type I Transmembrane Protein, Controls ARF1-dependent Resensitization of Protease-activated Receptor-2 by Influence on Receptor TraffickingThe Journal of Biological Chemistry 282 (2007) 30246–30255LuoWB, Wang YF,and Reiser GWB
Asparagine Synthetase
1732-1
Histamine Suppresses Fibulin-5 and Insulin-like Growth Factor-II Receptor Expression in MelanomaCancer Res 68 (2008) 1997-2005Pos Z, Wiener Z, Pocza P, et alIHC
ATF-2
1246-1
Dephosphorylation of β-Arrestin 1 in GlioblastomasJ Neuropathol Exp Neurol. 68 (2009) 535-541Mandell JW, Glass G, Gianchandani EP, et alWB, IHC
ATF-2
1246-1
Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signalingJ. Clin. Invest. 118 (2008) 1074–1084Balabanian K, Levoye A, Klemm L, et alWB
Atg7
2054-1
Pancreatic cancers require autophagy for tumor growthGenes Dev 25 (2011) 717-729Yang S, Wang X, Contino G, et al
ATM
1549-1
Selenium Compounds Activate ATM-dependent DNA Damage Response via the Mismatch Repair Protein hMLH1 in Colorectal Cancer CellsJ Biol Chem 285 (2010) 33010-33017Qi Y, Schoene NW, Lartey FM, et al
ATM
1549-1
Multiple DNA Damage Signaling and Repair Pathways Deregulated by Simian Virus 40 Large T AntigenJ Virol 84 (2010) 8007-8020Boichuk S, Hu L, Hein J, et al
ATM
1549-1
ATM-mediated response to DNA double strand breaks in human neurons derived from stem cellsDNA repair 6 (2007) 128–134Bitona S, Gropp M, Itsyksonb P, et alICC
ATM
1549-1
Nuclear Ataxia-Telangiectasia Mutated (ATM) Mediates the Cellular Response to DNA Double Strand Breaks in Human Neuron-like CellsThe Journal of Biological Chemistry 281 (2006) 17482–17491Biton S, Dar I, Mittelman L, et alICC
ATM
1549-1
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growthVirology 375 (2008) 13–23Li H, Baskaran R, Krisky DM, et alWB
ATM
1549-1
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand crosslink-induced DNA double strand breaksMol. Biol. Cell 19 (2008) 3923 - 3933Cheng WH, Muftic D, Muftuoglu M, et alWB, ICC
ATM
1549-1
Induction of oncogene addiction shift to NF-κB by camptothecin in solid tumor cellsBiochem Biophys Res Commun 390 (2009) 60-64Togano T, Sasaki M, Watanabe M, et alWB
ATM
1549-1
Adeno-Associated Virus Replication Induces a DNA Damage Response Coordinated by DNA-Dependent Protein KinaseJ. Virol. 83 (2009) 6269 -6278Schwartz RA, Carson CT, Schuberth C, et alIP
ATM
1549-1
Selenium Compounds Activate Early Barriers of TumorigenesisJ Biol Chem 285 (2010) 12055-12062Wu M, Kang MM, Schoene NW, et al
ATM
1549-1
ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brainDNA repair 6 ( 2007 ) 1698–1707Gorodetsky E, Calkins S , Ahn J, et alICC
ATM
1549-1
Differential Requirements of the C Terminus of Nbs1 in Suppressing Adenovirus DNA Replication and Promoting Concatemer FormationJournal of Virology 82 (2008) 8362–8372Lakdawala SS, Schwartz RA, Ferenchak K, et alWB
ATM Phospho (pS1981)
2152-1
Enhanced H2AX Phosphorylation, DNA Replication Fork Arrest, and Cell Death in the Absence of Chk1Mol Biol Cell 21 (2010) 739-752Gagou ME, Zuazua-Villar P, Meuth M
ATM Phospho (pS1981)
2152-1
Multiple DNA Damage Signaling and Repair Pathways Deregulated by Simian Virus 40 Large T AntigenJ Virol 84 (2010) 8007-8020Boichuk S, Hu L, Hein J, et al
ATM Phospho (pS1981)
2152-1
ATM/ATR and SMAD3 Pathways Contribute to 3-Indole-induced G1 Arrest in Cancer Cells and Xenograft ModelsAnticancer Res 31 (2011) 203-208Huang SM, Lu KT, Wang YCWB
ATM Phospho (pS1981)
2152-1
Lack of DNA Polymerase θ (POLQ) Radiosensitizes Bone Marrow Stromal Cells In Vitro and Increases Reticulocyte Micronuclei after Total-Body IrradiationRadiat Res 172 (2009) 165-174Goff JP, Shields DS, Seki M, et alIP
ATM Phospho (pS1981)
2152-1
ATM Deficiency Sensitizes Mantle Cell Lymphoma Cells to Poly(ADP-Ribose) Polymerase-1 InhibitorsMol Cancer Ther 9 (2010) 347-357Williamson CT, Muzik H, Turhan AG, et al
ATM Phospho (pS1981)
2152-1
Ionizing Radiation Induces Ataxia Telangiectasia Mutated-Dependent Checkpoint Signaling and G2 But Not G1 Cell Cycle Arrest in Pluripotent Human Embryonic Stem CellsStem Cells 27 (2009) 1822 -1835Momcilovic O, Choi S, Varum S, et al
ATM Phospho (pS1981)
2152-1
High DNA Methyltransferase 3B Expression Mediates 5-Aza-Deoxycytidine Hypersensitivity in Testicular Germ Cell TumorsCancer Res. 69 (2009) 9360-9366Beyrouthy MJ, Garner KM, Hever MP, et al
ATM Phospho (pS1981)
2152-1
Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylationMol Cancer 9 (201) :34Kobayashi J, Kato A, Ota Y, et alICC
ATM Phospho (pS1981)
2152-1
Radiation-induced mitotic catastrophe in PARG-deficient cellsJ. Cell Sci. 122 (2009) 1990 - 2002Amé JC, Fouquerel E, Gauthier LR, et al
ATM Phospho (pS1981)
2152-1
53BP1-dependent robust localized KAP‑1 phosphorylation is essential for heterochromatic DNA double-strand break repairNat Cell Biol 12 (2010) 177-184Noon AT, Shibata A, Rief N, et alICC
ATM Phospho (pS1981)
2152-1
ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA DamageSci Signal 3 (2010) rs3Bensimon A, Schmidt A, Ziv Y, et al
ATM Phospho (pS1981)
2152-1
Transient ATM Kinase Inhibition Disrupts DNA Damage–Induced Sister Chromatid ExchangeSci Signal 3 (2010) ra44White JS, Choi S, Bakkenist CJWB
ATM Phospho (pS1981)
2152-1
Induction of oncogene addiction shift to NF-κB by camptothecin in solid tumor cellsBiochem Biophys Res Commun 390 (2009) 60-64Togano T, Sasaki M, Watanabe M, et alWB
ATM Phospho (pS1981)
2152-1
Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic InstabilityCancer Res 70 (2010) 925-935Pires IM, Bencokova Z, Milani M, et al
ATP-citrate lyase (C-term) protein
1699-1
Timosaponin AIII Is Preferentially Cytotoxic to Tumor Cells through Inhibition of mTOR and Induction of ER StressPLoS One 4 (2009) e7283King FW, Fong S, Griffin C, et alWB
ATP-citrate lyase (C-term) protein
1699-1
Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: Knockdown of SCOT inhibits insulin release in rat insulinoma cellsArch Biochem Biophys 499 (2010) 62-68Hasan NM, Longacre MJ, Seed Ahmed M, et alWB
ATP-citrate lyase Phospho (pT447/pS451)
1914-1
ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cellsJ Biol Chem 285 (2010) 32606-32615Chu KY, Lin Y, Hendel A, et al
Aurora-A
1800-1
Co-treatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cellsClin Cancer Res. 14 (2008) 6106-6115Fiskus W, Wang Y, Joshi R, et alWB
Aurora-B
1788-1
Analysis of Aurora B kinase in non-Hodgkin lymphomaLab Invest 89 (2009) 1364-1373Ikezoe T, Takeuchi T, Yang J, et alIHC
Aurora-B
1788-1
Co-treatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cellsClin Cancer Res. 14 (2008) 6106-6115Fiskus W, Wang Y, Joshi R, et alWB
Aurora-B
1788-1
Giant Cell Glioblastoma Is Associated With Altered Aurora B Expression and Concomitant p53 MutationJ Neuropathol Exp Neurol 69 (2010 632-642Temme A, Geiger KD, Wiedemuth R, et alIHC
Bad (N-term)
1541-1
Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neuronsProceedings of the National Academy of Sciences 105 (2008) 4892–4897Miyawaki T, Mashiko T, Ofengeim D, et alWB, IP
Bak
1542-1
Identification of Expression Signatures Predictive of Sensitivity to the Bcl-2 Family Member Inhibitor ABT-263 in Small Cell Lung Carcinoma and Leukemia/Lymphoma Cell LinesMol Cancer Ther 9 (2010) 545-557Tahir SK, Wass J, Joseph MK, et al
Bax
1063-1
Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effectJ Biol Chem. 284 (2009) 9692-9699Eliseev RA, Malecki J, Lester T, et alIP
Bax
1063-1
Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivityto apoptosisOncogene 27 (2008) 3605–3614Eliseev RA, Dong YF, Sampson E, et alWB
Bax
1063-1
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animalsNucleic Acids Research 35 (2007) 687-700Swayze EE, Siwkowski AM, Wancewicz EV, et alIHC
Bax
1063-1
Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosisNephrol Dial Transplant 26 (2011) 814-822Kang KP, Park SK, Kim DH, et al
Bax
1063-1
Lipopolysaccharide extends the lifespan of mouse primary-cultured microgliaBrain Research 1279 (2009) 9-20Kaneko YS, Nakashima A, Mori K, et alWB
Bax
1063-1
Neuroprotective effect of transcorneal electrical stimulation on light-induced photoreceptor degenerationExp Neurol. 219 (2009) 439-452Ni YQ, Gan DK, Xu HD, et alIHC
Bcl-2
1017-1
Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survivalBlood 114 (2009) 2273 - 2279Johnson NA, Savage KJ, Ludkovski O, et alIHC
Bcl-2
1017-1
Neuroprotective Function of Cellular Prion Protein in a Mouse Model of Amyotrophic Lateral SclerosisAm J Pathol 176 (2010) 1409-1420Steinacker P, Hawlik A, Lehnert S, et alWB
Bcl-2
1017-1
β-hydroxy-β-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathwaysBiochim Biophys Acta. 1793 (2009) 755-763Kornasio R, Riederer I, Butler-Browne G, et alICC
Bcl-2
1017-1
EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteinsMol. Cancer Ther. 8 (2009) 2674 - 2683Winkler J, Martin-Killias P, Plückthun A, et al
Bcl-2
1017-1
Immunohistochemistry in diagnostic surgical pathology: contributions of protein life-cycle, use of evidence-based methods and data normalization on interpretation of immunohistochemical stainsInt J Clin Exp Pathol 3 (2009) 169-176Idikio HAIHC
Bcl-2
1017-1
Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effectJ Biol Chem. 284 (2009) 9692-9699Eliseev RA, Malecki J, Lester T, et alIP
Bcl-2
1017-1
Escherichia coli Subtilase Cytotoxin Induces Apoptosis Regulated by Host Bcl-2 Family Proteins Bax/BakInfect Immun 78 (2010) 4691-4696May KL, Paton JC, Paton AW
Bcl-2
1017-1
MYC gene re-arrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapyBlood 114 (2009) 3533 - 3537Savage KJ, Johnson NA, Ben-Neriah S, et alIHC
Bcl-2
1017-1
BH3 Profiling Identifies Three Distinct Classes of ApoptoticBlockstoPredictResponsetoABT-737 and Conventional Chemotherapeutic AgentsCancer Cell 12, 171–185, August 2007Deng J, Carlson N, Takeyama K, et alIP
Bcl-2
1017-1
Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1Blood 115 (2010) 3304-3313Yecies D, Carlson NE, Deng J, et al
Bcl-2
1017-1
Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivityto apoptosisOncogene 27 (2008) 3605–3614Eliseev RA, Dong YF, Sampson E, et alWB
Bcl-2
1017-1
Escherichia coli Subtilase Cytotoxin Induces Apoptosis Regulated by Host Bcl-2 Family Proteins, Bax/BakInfect Immun 78 (2010) 4691-4696May KL, Paton JC, Paton AW
Bcl-2
1017-1
Differential Dependence on Beclin 1 for the Regulation of Pro-Survival Autophagy by Bcl-2 and Bcl-xL in HCT116 Colorectal Cancer CellsPLoS One 5 (2010) e8755Priault M, Hue E, Marhuenda F, et alIP
Bcl-2
1017-1
An Ang1-Tie2-PI3K axis in Neural Progenitor Cells Initiates Survival Responses Against Oxygen And Glucose DeprivationNeuroscience 160 (2009) 371-381Bai Y, Meng Z, Cui M, et alWB
Bcl-2
1017-1
BCL2 protein expression in follicular lymphomas with t(14;18) chromosomal translocationsBritish Journal of Haematology 144 (2009) 716-725Masir N, Campbell LJ, Goff LK, et alIHC
Bcl-2 Family Ab Sampler Kit
5001-1
Synergistic antiproliferative effect of arsenic trioxide combined with bortezomib in HL60 cell line and primary blasts from patients affected by myeloproliferative disordersCancer Genet Cytogenet 199 (2010) 110-120Canestraro M, Galimberti S, Savli H, et alFC
Bcl-2 Family Ab Sampler Kit
5001-1
ITF2357 Interferes with Apoptosis and Inflammatory Pathways in the HL-60 Model: A Gene Expression StudyAnticancer Res 30 (2010) 4525-4535Galimberti S, Canestraro M, Savli H, et al
Bcl-x
1018-1
Differential Dependence on Beclin 1 for the Regulation of Pro-Survival Autophagy by Bcl-2 and Bcl-xL in HCT116 Colorectal Cancer CellsPLoS One 5 (2010) e8755Priault M, Hue E, Marhuenda F, et alIP
Bcl-x
1018-1
β-hydroxy-β-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathwaysBiochim Biophys Acta. 1793 (2009) 755-763Kornasio R, Riederer I, Butler-Browne G, et alICC
Bcl-x
1018-1
Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family membersJ. Cell Biol. 185 (2009) 279 - 290Gallenne T, Gautier F, Oliver L, et alIP
Bcl-x
1018-1
Bax Activation by Engagement with, Then Release from, the BH3 Binding Site of Bcl-xLMol Cell Biol 31 (2011) 832-844Gautier F, Guillemin Y, Cartron PF, et al
Bcl-x
1018-1
Immunoexpression of Bcl-x in squamous cell carcinoma and keratoacanthoma: differences in pattern and correlation with pathobiologyHistopathology 55 (2009) 338-345Tan KB, Lee YSIHC
Bcl-x
1018-1
Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family membersJ Cell Biol 185 (2009) 279-290Gallenne T, Gautier F, Oliver L, et alIP
Bcl-x
1018-1
Proteomic and Functional Analyses Reveal a Dual Molecular Mechanism Underlying Arsenic-Induced Apoptosis in Human Multiple Myeloma CellsJ. Proteome Res. 8 (2009) 3006–3019Ge F, Lu XP, Zeng HL, et alWB
Beclin-1
2026-1
Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivoCancer Gene The 17 (2010) 109-119Yang C, Tong Y, Ni W, et alIP
Beta-Actin
1854-1
14-3-3 ζ/τ heterodimers regulate Slingshot activity in migrating keratinocytesBiochemical and Biophysical Research Communications 383 (2009) 450-454Kligys K, Yao J, Yu DH, et alWB
Beta-Actin
1854-1
The Slingshot Family of Phosphatases Mediates Rac1 Regulation of Cofilin Phosphorylation, Laminin-332 Organization, and Motility Behavior of KeratinocytesThe Journal of Biological Chemistry 282 (2007) 32520–32528Kligys K, Claiborne JN, DeBiase PJ, et alWB
Beta-Actin
1854-1
Differential proteomic characterization between normal peritoneal fluid and diabetic peritoneal dialysateNephrol Dial Transplant 25 (2010) 1955-1963Wang HY, Tian YF, Chien CC, et alWB
Beta-ARK1/GRK2 (C-term)
1516-1
Pasteurella multocida toxin activates Gβγ dimers of heterotrimeric G proteinsCellular Signalling 21 (2009) 551-558Preuß I, Kurig B, Nurnberg B, et alWB
Beta-ARK1/GRK2 (C-term)
1516-1
Cardioprotective Effect of Histamine H3-Receptor Activation: Pivotal Role of Gβγ-Dependent Inhibition of Voltage-Operated Ca2+ ChannelsJ. Pharmacol. Exp. Ther. 326 (2008) 871 - 878Morrey C, Estephan R, Abbott GW, et alWB
Beta-ARK1/GRK2 (C-term)
1516-1
Spatiotemporal Differences in CXCL12 Expression and Cyclic AMP Underlie the Unique Pattern of Optic Glioma Growth in Neurofibromatosis TypeCancer Res 67 (2007) 8588–8595Warrington NM, Woerner BM, Daginakatte GC, et alWB
Beta-Arrestin 1 Phospho (pS412)
1109-1
Dephosphorylation of β-Arrestin 1 in GlioblastomasJ Neuropathol Exp Neurol. 68 (2009) 535-541Mandell JW, Glass G, Gianchandani EP, et alWB, IHC
Beta-Catenin
1247-1
Wnt pathway-related gene expression during malignant progression in ulcerative colitisActa histochemica 109 (2007) 266-272Dekkena HV, Winka JC, Vissersa KJ, et alIHC
Beta-Catenin
1247-1
Targeted Overexpression of EZH2 in the Mammary Gland Disrupts Ductal Morphogenesis and Causes Epithelial HyperplasiaAm. J. Pathol. 175 (2009) 1246 - 1254Li X, Gonzalez ME, Toy K, et al
Beta-Catenin
1247-1
A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal TumorigenesisPLoS Genet 5 (2009) e1000547Gaspar C, Franken P, Molenaar L, et alIHC
Beta-Tubulin
1799-1
Live-Cell Imaging in Caenorhabditis elegans Reveals the Distinct Roles of Dynamin Self-Assembly and Guanosine Triphosphate Hydrolysis in the Removal of Apoptotic CellsMol Biol Cell 21 (2010) 610-629He B, Yu X, Margolis M, et al
Beta-Tubulin
1879-1
ADAM15 Exerts an Antiapoptotic Effect on Osteoarthritic Chondrocytes via Up-Regulation of the X-Linked Inhibitor of ApoptosisArthritis Rheum 62 (2010) 1372-1382Böhm B, Hess S, Krause K, et alWB
Bim
1036-1
BIM Regulates Apoptosis during Mammary Ductal Morphogenesis, and Its Absence Reveals Alternative Cell Death MechanismsDevelopmental Cell 12 (2007) 221–234Mailleux AA, Overholtzer M, Schmelzle T, et alIHC
Bim
1036-1
TGFβ-mediated apoptosis of Burkitt’s lymphoma BL41cells is associated with the relocation of mitochondrial BimELOncogene 27 (2008) 3446–3456Clybouw C, Mchichi B EL , Hadji A, et alWB, IP
Bim
1036-1
BimL upregulation induced by BCR cross-linking in BL41 Burkitt’s lymphoma results from a splicing mechanism of the BimEL mRNABiochemical and Biophysical Research Communications 383 (2009) 32-36Clybouw C, Hadji A, ElMchichi B, et alWB
Bim
1036-1
Different Changes in Protein and Phosphoprotein Levels Result from Serum Starvation of High-Grade Glioma and Adenocarcinoma Cell LinesJ Proteome Res 9 (2010) 179-191Levin VA, Panchabhai SC, Shen L, et alWB
Bim
1036-1
The BH3α -Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent MannerJ Biol Chem 286 (2011) 9382-9392Kazi A, Sun J, Doi K, et al
Bim
1036-1
Effective gene-viral therapy of leukemia by a new fiber chimeric oncolytic adenovirus expressing TRAIL: in vitro and in vivo evaluationMol. Cancer Ther. 8 (2009) 1387 - 1397Jin J, Liu H, Yang CM, et al
Bim
1036-1
The miR-17-92 Cluster of MicroRNAs Confers Tumorigenicity by Inhibiting Oncogene-Induced SenescenceCancer Res 70 (2010) 8547-8557Hong L, Lai M, Chen M, et al
Bim
1036-1
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytesNature Immunology 9 (2008) 405-414Xiao CC, Srinivasan L, Calado DP, et alICC
Btk Phospho (pY551)
1685-1
In Vivo Significance of ITK-SLP-76 Interaction in Cytokine ProductionMol Cell Biol 30 (2010) 3596-3609Grasis JA, Guimond DM, Cam NR, et al
Btk Phospho (pY551)
1685-1
Cbl-b Is a Novel Physiologic Regulator of Glycoprotein VI-dependent Platelet ActivationJ Biol Chem 285 (2010) 17282-17291Daniel JL, Dangelmaier CA, Mada S, et al
c-Jun Phospho (pS63)
1527-1
Jun NH2-terminal kinase (JNK) prevents nuclear β-catenin accumulation and regulates axis formation in Xenopus embryosPNAS 103 (2006) 16313–16318Liao GH, Tao QH, Kofron M, et alWB
c-Jun Phospho (pS63)
1527-1
Overexpression of matrix metalloproteinase 1 in dermal fibroblasts from DNA repair- eficient/ cancer-prone xeroderma pigmentosum group C patientsOncogene 27 (2008) 5223–5232Frechet M, Warrick E, Vioux C, et alWB
c-Kit/CD117
1522-1
Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic MelanomaClin. Cancer Res. 15 (2009) 7538-7546Davies MA, Stemke-Hale K, Lin E, et al
c-Kit/CD117
1522-1
C-kit-targeted imaging of gastrointestinal stromal tumor using radiolabeled anti-c-kit monoclonal antibody in a mouse tumor modelNucl Med Biol 37 (2010) 179-187Sogawa C, Tsuji AB, Sudo H, et alWB, ICC
c-Kit/CD117
1522-1
Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatmentCancer Sci 101 (2010) 1270–1278Sakamoto K, Sakurai S, Kanda T, et alIHC
c-Kit/CD117
1522-1
Antigen retrieval and primary antibody type affect sensitivity but not specificity of CD117 immunohistochemistryHistopathology 54 (2009) 529–538Wong NA, Melegh ZIHC
c-Kit/CD117
1522-1
Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatmentCancer Sci 101 (2010) 1270-1278Sakamoto K, Sakurai S, Kanda T, et alIHC
c-Kit/CD117
1522-1
Comparative study using rabbit-derived polyclonal, mouse-derived monoclonal, and rabbit-derived monoclonal antibodies for KIT immunostaining in GIST and other tumorsPathology International 57 (2007) 200–204Saito M, Sakurai S, Motegi A, et alIHC
c-Myb
1792-1
Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndromeLeuk Res 34 (2010) 328-334Hussein K, Theophile K, Büsche G, et alIHC
c-Myc
1472-1
Up-regulation of miR-21 by HER2/neu Signaling Promotes Cell InvasionJ. Biol. Chem. 284 (2009) 18515 - 18524Huang TH, Wu FT, Loeb GB, et alWB
c-Myc
1472-1
Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and apoptosis via the extracellular-regulated kinase 1/2 pathway and other cancer signaling genesJ Nutr 139 (2009) 1613-1618Zeng H, Wu M, Botnen JHWB
c-Myc
1472-1
Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor BortezomibCancer Res 70 (2010) 4318-4326Chen S, Blank JL, Peters T, et al
c-Myc
1472-1
Methylselenol, a Selenium Metabolite, Induces Cell Cycle Arrest in G1 Phase and Apoptosis via the Extracellular-Regulated Kinase 1/2 Pathway and Other Cancer Signaling GenesJ. Nutr. 139 (2009) 1613 - 1618Zeng HW, Wu M, Botnen JHWB
c-Myc
1472-1
Opposing microRNA families regulate selfrenewal in mouse embryonic stem cellsNature 463 (2010) 621-626Melton C, Judson RL, Blelloch RWB
c-Myc
1472-1
Altered Subcellular Localization of c-Myc Protein Identifies Aggressive B-cell Lymphomas Harboring c-MYC TranslocationAm J Surg Pathol 34 (2010) 882-891Ruzinova MB, Caron T, Rodig SJIHC
c-Myc
1472-1
Methylselenol, a Selenium Metabolite, Induces Cell Cycle Arrest in G1 Phase and Apoptosis via the Extracellular-Regulated Kinase 1/2 Pathway and Other Cancer Signaling GenesJ. Nutr.139 (2009) 1613 - 1618Zeng HW, Wu M, Botnen JH
c-Myc
1472-1
Cell Cycle Re-Entry and Mitochondrial Defects in Myc- Mediated Hypertrophic Cardiomyopathy and Heart FailurePLoS One 4 (2009) e7172Lee HG, Chen Q, Wolfram JA, et alICC
c-Myc
1472-1
MYC regulation of a “poor-prognosis” metastatic cancer cell stateProc Natl Acad Sci U S A 107 (2010) 3698-3703Wolfer A, Wittner BS, Irimia D, et alIHC
c-Myc
1472-1
Altered AIB1 or AIB1 deta 3 Expression Impacts ERα Effects on Mammary Gland Stromal and Epithelial ContentMol Endocrinol 25 (2011) 549-563Nakles RE, Shiffert MT, Díaz-Cruz ES, et al
c-Myc
1472-1
UVC inhibits HIF-1a protein translation by a DNA damage- and topoisomerase I-independent pathwayOncogene 26 (2007) 6875–6884Rapisarda A and Melillo GWB
c-Myc
1472-1
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesisMod Pathol 21 (2008) 1156-1167Gurel B, Iwata T, Koh CM, et alWB, IHC
c-Myc
1472-1
MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial CellsPLoS One 5 (2010) e9427Iwata T, Schultz D, Hicks J, et alWB
c-Myc Phospho (pT58/pS62)
1203-1
Brivanib Alaninate, a Dual Inhibitor of Vascular Endothelial Growth FactorReceptor and Fibroblast Growth Factor Receptor Tyrosine Kinases, Induces Growth Inhibition in MouseClin Cancer Res. 14 (2008) 6146-6153Huynh H, Ngo VC, Fargnoli J, et alWB
C/EBP alpha
1704-1
The EBV BZLF1 protein inhibits TNFR1 expression through effects on cellular C/EBP proteinsJ Virol 84 (2010) 12362-12374Bristol JA, Robinson AR, Barlow EA, et al
C/EBP alpha
1704-1
The Epstein-Barr Virus BZLF1 Protein Inhibits Tumor Necrosis Factor Receptor 1 Expression through Effects on Cellular C/EBP ProteinsJ Virol 84 (2010) 12362-12374Bristol JA, Robinson AR, Barlow EA, et al
C/EBP alpha
1704-1
CCAAT/enhancer binding proteins and regulate the tumor necrosis factor receptor 1 gene promoterMol Immunol. 46 (2009) 2706-2713Bristol JA, Morrison TE, Kenney SCWB, IP
C1q
5096-1
A Dramatic Increase of C1q Protein in the CNS during Normal AgingThe Journal of NeuroscienceAlexander H. Stephan et al. IHC
Calmodulin (CaM)
1716-1
Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: Mechanisms for aquaporin 2 down-regulation and cellular proliferationPNAS 105 (2008) 3634–3639Nielsen J, Hoffert JD, Knepper MA, et al
Calmodulin (CaM)
1716-1
Neurogranin enhances synaptic strength through its interaction with calmodulinEMBO J. (2009) 1–13Zhong L, Cherry T, Bies CE, et alWB
Calmodulin (CaM)
1716-1
Neurogranin enhances synaptic strength through its interaction with calmodulinEMBO J 28 (2009) 3027-3039Zhong L, Cherry T, Bies CE, et alWB
Calmodulin (CaM)
1716-1
Intracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytesBiochem Biophys Res Commun 396 (2010) 515-521Gangopadhyay JP, Ikemoto NICC
Calponin-1
1806-1
Stromal Fibroblasts Activated by Tumor Cells Promote Angiogenesis in Mouse Gastric CancerJ. Biol. Chem. 283 (2008) 19864 - 19871Guo XY, Oshima H, Kitmura T, et alIHC
CaMKII
2048-1
Driving fast-spiking cells induces gamma rhythm and controls sensory responsesNature 459 (2009) 663-667Cardin JA, Carlen M, Meletis K, et alIHC
Caspase-3
1087-1
Apoptosis in the small intestine of neonatal rat using blue light-emitting diode devices and conventional halogen-quartz devices in phototherapyPediatr Surg Int 24 (2008) 837–842Tanaka K, Hashimoto H, Tachibana T, et alIHC
Caspase-3 (Active)
1476-1
Formation of Dopamine Adducts Derived From Brain Ployunsaturated Fatty Acids: Mechanism for Parkinson's DiseaseJ. Biol. Chem. 283 (2008) 34887 - 34895Liu XB, Yamada N, Maruyama W, et alWB
Caspase-3 (Active)
1476-1
Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancerOncogene 27 (2008) 2877–2885Cangemi R, Mensah A, Albertini V, et alWB
Caspase-3 (Active)
1476-1
Minocycline, a possible neuroprotective agent in Leber’s hereditary optic neuropathy (LHON): Studies of cybrid cells bearing 11778 mutationNeurobiology of Disease 28 (2007) 237–250Haroon MF, Fatima A, Schöler S, et alWB
Caspase-3 (Active)
1476-1
Neurolysosomal pathology in human prosaposin deWciency suggests essential neurotrophic function of prosaposinActa Neuropathol 113 (2007) 163–175Sikora J, Harzer K, Elleder MIHC
Caspase-3 (Active)
1476-1
The Characterization of Epithelial and Stromal Subsets of Candidate Stem/Progenitor Cells in the Human Adult ProstateEuropean Urology 53 (2008) 524–532Ceder JA, Jansson L, Ehrnstrom RA, et alICC
Caspase-3 (Active)
1476-1
Induced pluripotent stem cells derived from mouse models of lysosomal storage disordersProc Natl Acad Sci U S A 107 (2010) 7886-7891Meng XL, Shen JS, Kawagoe S, et alWB
Caspase-8
1007-1
Prolonged low-dose administration of the cyclooxygenase-2 inhibitor celecoxib enhances the antitumor activity of irinotecan against neuroblastoma xenograftsCancer Sci. 100 (2009) 2193-2201Kaneko M, Kaneko S, Suzuki K.WB
Catalase
2024-1
A novel giant peroxisomal superoxide dismutase motif-containing proteinFree Radical Biology & Medicine 48 (2010) 811–820Toutzaris D, Lewerenz J, Albrecht P, et alConfocal microscopy
Cbl Phospho (pY774)
1160-1
Diacylglycerol Kinase and Protein Kinase C Modulate Epidermal Growth Factor Receptor Abundance and Degradation through Ubiquitin-specific Protease 8J Biol Chem 285 (2010) 6952-6959Cai J, Crotty TM, Reichert E, et al
CCR2/CKR2
2068-1
Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factor Signaling during Peripheral Organ InflammationJ. Neurosci. 29 (2009) 2089 - 2102D’Mello C, Le T, Swain MGICC
CCR2/CKR2
2068-1
Inhibitory ITAM Signaling by Fc RI-FcR Chain Controls Multiple Activating Responses and Prevents Renal InflammationJournal of Immunology 180 (2008) 2669–2678Kanamaru Y, Pfirsch S, Aloulou M, et alWB
CCR2/CKR2
2068-1
Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammationPain 148 (2010) 509-518Fu ES, Zhang YP, Sagen J, et alIHC
CCR2/CKR2
2068-1
Transgenic Inhibition of Astroglial NF-κB Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System InflammationJ Immunol 182 (2009) 2628–2640Brambilla R, Persaud T, Hu XC, et alIHC
CCR2/CKR2
2068-1
Opposite Roles of CCR2 and CX3CR1 Macrophages in Alkali-Induced Corneal NeovascularizationCornea. 28 (2009) 562-569Lu PR, Li LB, Liu GQ, et alIHC
CCR2/CKR2
2068-1
Suppression of the lipopolysaccharide-induced expression of MARCKS-related protein (MRP) affects transmigration in activated RAW264.7 cellsCellular Immunology 256 (2009) 92–98Chun KR, Bae EM, Kim JK, et alFC
CCR2/CKR2
2068-1
Crucial Contribution of Thymic Sirp+ Conventional Dendritic Cells to Central Tolerance against Blood-Borne Antigens in a CCR2-Dependent MannerJ. Immunol. 183 (2009) 3053 - 3063Baba T, Nakamoto Y, Mukaida N
CCR2/CKR2
2068-1
The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-β, increases podocyte motility and albumin permeabilityAm J Physiol Renal Physiol. 297 (2009) F85-F94Lee EY, Chung CH, Khoury CC, et alICC
CCR2/CKR2
2068-1
Force-Dependent Development of Neuropathic Central Pain and Time-Related CCL2/CCR2 Expression after Graded Spinal Cord Contusion Injuries of the RatJournal of Neurotrauma 25 (2008) 427-448Knerlich-Lukoschus F, Juraschek M, Blomer U, et alICC
CCR2/CKR2
2068-1
The C Terminus of Mouse Monocyte Chemoattractant Protein 1 (MCP1) Mediates MCP1 Dimerization while Blocking Its Chemotactic PotencyJ Biol Chem 285 (2010) 31509-31516Yao Y, Tsirka SE
CCR2/CKR2
2068-1
Crucial Contribution of Thymic Sirp+ Conventional Dendritic Cells to Central Tolerance against Blood-Borne Antigens in a CCR2-Dependent MannerJ. Immunol. 183 (2009) 3053 - 3063Baba T, Nakamoto Y, Mukaida N
CCR2/CKR2
2068-1
Effect of the Monocyte Chemoattractant Protein-1/CC Chemokine Receptor 2 System on Nephrin Expression in Streptozotocin-Treated Mice and Human Cultured PodocytesDiabetes58 (2009) 2109 - 2118Tarabra E, Giunti S, Barutta F, et alIHC
CCR2/CKR2
2068-1
The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-β, increases podocyte motility and albumin permeabilityAm J Physiol Renal Physiol 297 (2009) F85 - F94Lee EY, Chung CH, Khoury CC, et al
CCR2/CKR2
2068-1
Effect of the Monocyte Chemoattractant Protein-1/CC Chemokine Receptor 2 System on Nephrin Expression in Streptozotocin-Treated Mice and Human Cultured PodocytesDiabetes58 (2009) 2109 - 2118Tarabra E, Giunti S, Barutta F, et al
CCR2/CKR2
2068-1
Epstein-Barr Virus (EBV)-Infected Monocytes Facilitate Dissemination of EBV within the Oral Mucosal EpitheliumJournal of Virology 81 (2007) 5484–5496Tugizov S, Herrera R, Veluppillai P, et al
CCR2/CKR2
2068-1
Therapy with Nonglycosaminoglycan-Binding Mutant CCL7: A Novel Strategy to Limit Allograft InflammationAm J Transplant 10 (2010) 47-58Ali S, O'Boyle G, Hepplewhite P, et alIHC
CCR2/CKR2
2068-1
The Monocyte Chemoattractant Protein-1/Cognate CC Chemokine Receptor 2 System Affects Cell Motility in Cultured Human PodocytesAm J Pathol 171 (2007) 1789-1799Burt D, Salvidio G, Tarabra E, et alICC
CCR3/CKR3
2031-1
Macrophage Inflammatory Protein–1δ: A Novel Osteoclast Stimulating Factor Secreted by Renal Cell Carcinoma Bone MetastasisCancer Res 68 (2008) 1261-1266Kominsky SL, Abdelmagid SM, Doucet M, et alWB
CCR7/CKR7
2059-1
Constitutive Expression of the α4 Integrin Correlates with Tumorigenicity and Lymph Node Metastasis of the B16 Murine MelanomaNeoplasia 12 (2010) 173-182Rebhun RB, Cheng H, Gershenwald JE, et alWB
CCR7/CKR7
2059-1
Acute in vivo exposure to interferon-γ enables resident brain dendritic cells to become effective antigen presenting cellsProc Natl Acad Sci U S A 106 (2009) 20918-10923Gottfried-Blackmore A, Kaunzner UW, Idoyaga J, et alWB
CD14
2641-1
LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases β1 Integrin-Mediated Cell Adhesion and Liver MetastasisCancer Res 71 (2011) 1989-1998Simon Rousseau, and Lorenzo E. Ferri
CD14
2641-1
Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cellsAm J Pathol 176 (2010) 968-980Kayamori K, Sakamoto K, Nakashima T, et alIHC
CD20
1632-1
BDNF and its receptors in human myasthenic thymus: Implications for cell fate in thymic pathologyJournal of Neuroimmunology 197 (2008) 128–139Berzi A, Ayata CK, Cavalcante P, et alICC
CD20
1632-1
Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cellsAm J Pathol 176 (2010) 968-980Kayamori K, Sakamoto K, Nakashima T, et alIHC
CD20
1632-1
The autophilic anti-CD20 antibody DXL625 displays enhanced potency due to lipid raft-dependent induction of apoptosisAnticancer Drugs 21 (2010) 532-542Bingaman MG, Basu GD, Golding TC, et alFC
CD20
1632-1
Basophils in the giant papillae of chronic allergic keratoconjunctivitisBr J Ophthalmol 94 (2010) 513-518Matsuda A, Ebihara N, Yokoi N, et alIHC
CD22
1638-1
Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid β-lactamase displayProtein Eng Des Sel 24 (2011) 351-360Bannister D, Popovic B, Sridharan S, et al
CD22
1638-1
B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9- O -acetyl sialic acid esteraseJ. Exp. Med. 206 (2009) 125 - 138Cariappa A, Takematsu H, Liu H, et alIP
CD3 zeta Phospho (pY83)
2317-1
Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450Blood 115 (2010 ) 4174-4184Robles-Valero J, Martín-Cófreces NB, Lamana A, et al
CD44
1998-1
Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenograftsPNAS 105 (2008) 5774–5779Horwitz KB, Dye WW, Harrell JC, et alIHC
CD44
1998-1
Vascular Endothelial Growth Factor Secreted by Activated Stroma Enhances Angiogenesis and Hormone-Independent Growth of Estrogen Receptor–Positive Breast CancerCancer Res 70 (2010) 2655-2664Pinto MP, Badtke MM, Dudevoir ML, et al
Cdc25C
1302-1
Ochratoxin A induces G2 phase arrest in human gastric epithelium GES-1 cells in vitroToxicol Lett 193 (2010) 152-158Cui J, Xing L, Li Z, et alWB
Cdc25C Phospho (pS216)
1190-1
XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell lineChem Biol Interact 183 (2010) 133-141Ye Z, Chen Z, Chen W, et alWB
Cdk2 (C-term)
1134-1
Stem cell factor induces ERM proteins phosphorylation through PI3K activation to mediate melanocyte proliferation and migrationPigment Cell Melanoma Res. 22 (2009) 77–85Jeon S, Kim NH, Kim JY, et alWB
CDX2
2475-1
GATA3 Is Selectively Expressed in the Trophectoderm of Peri-implantation Embryo and Directly Regulates Cdx2 Gene ExpressionJ Biol Chem. 284 (2009) 28729-28737Home P, Ray S, Dutta D, et alWB
Chk1 (C-term)
1740-1
The E2F-Regulated Gene Chk1 Is Highly Expressed in Triple-Negative Estrogen Receptor /Progesterone Receptor /HER-2 Breast CarcinomasCancer Res 67 (2007) 6574–6481Verlinden L, Bempt IV, Eelen G, et alIHC
Chk1 antibody
S0009
hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced ApoptosisJ Biol Chem 286 (2011) 10411-10418Pabla N, Ma Z, McIlhatton MA, et alWB
Chk2 Phospho (pT68)
1126-1
The CHK2–BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cellsNat Cell Biol 12 (2010) 492-499Stolz A, Ertych N, Kienitz A, et alWB
cIAP2 antibody
S2700
TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP InhibitorsClin Cancer Res 16 (2010) 5734-5749Stadel D, Mohr A, Ref C, et al
CPI-17 alpha
1585-1
Calcium sensitivity and cooperativity of permeabilized rat mesenteric lymphaticsAm J Physiol Regul Integr Comp Physiol 294 (2008) R1524-R1532Dougherty PJ, Davis MJ, Zawieja DC, et alWB
Creb
1496-1
Human T-cell Leukemia Virus Type 1 Oncoprotein Tax Represses ZNF268 Expression through the cAMP-responsive Element-binding Protein/Activating Transcription Factor PathwayJ. Biol. Chem. 283 (2008) 16299 - 16308Wang D, Guo MX, Hu HM, et alEMSA
Creb Phospho (pS133)
1113-1
Synaptic Tagging and Capture: Differential Role of Distinct Calcium/Calmodulin Kinases in Protein Synthesis-Dependent Long-Term PotentiationJ Neurosci 30 (2010) 4981-4989Redondo RL, Okuno H, Spooner PA, et alICC
Crk/p38 Phospho (pY221)
2132-1
Effects of Thymoquinone in the Expression of Mucin 4 in Pancreatic Cancer Cells: Implications for the Development of Novel Cancer TherapiesMol Cancer Ther 9 (2010) 1419-1431Torres MP, Ponnusamy MP, Chakraborty S, et al
CXCR4
3108-1
Reassessment of CXCR4 Chemokine Receptor Expression in Human Normal and Neoplastic Tissues Using the Novel Rabbit Monoclonal Antibody UMB-2PLOS One 3(12):1 – 7, 2008Fisher T et al.IHC
CXCR4
3108-1
Cxcr7 controls neuronal migration by regulating chemokine responsivenessNeuronSánchez-Alcañiz JA, Haege S, et alIHC
Cyclin A2 (C-term)
1540-1
Material hepatic growth response to pregnancy in the mouseExp Biol Med (Maywood). (2011) 236(11):1322-32 Guoli Dai, Juan J Bustamante, et al
Cyclin B1 (C-term)
1495-1
Gene and protein expression markers of response to combined antiangiogenic and epidermal growth factor targeted therapy in renal cell carcinomaAnn Oncol 21 (2010) 1599-15606Tsavachidou-Fenner D, Tannir N, Tamboli P, et alWB
Cyclin B1 (C-term)
1495-1
Integrative Analysis of Cyclin Protein Levels Identifies Cyclin B1 as a Classifier and Predictor of Outcomes in Breast CancerClin. Cancer Res. 15 (2009) 3654 - 3662Agarwal R, Gonzalez-Angulo AM, Myhre S, et al
Cyclin B1 (C-term)
1495-1
PharmacodynamicMarkers of Perifosine EfficacyClin Cancer Res 13 (2007) 8421-7431Hennessy BT, Lu YL, Poradosu E, et alWB
Cyclin E1
1655-1
Material hepatic growth response to pregnancy in the mouseExp Biol Med (Maywood). (2011) 236(11):1322-32 Guoli Dai, Juan J Bustamante, et al
Cyclin E2
1775-1
Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-MycMol. Cell. Biol. 29 (2009) 4623 - 4639Caldon CE, Sergio CM, Schütte J, et alIP
Cytokeratin 10
2210-1
The Streptococcus pneumoniae adhesin PsrP binds to Keratin 10 on lung cellsMol Microbiol 73 (2009) 663-679Shivshankar P, Sanchez C, Rose LF, et alWB, IP
Cytokeratin 14
2001-1
Reconstruction of a human hemicornea through natural scaffolds compatible with the growth of corneal epithelial stem cells and stromal keratocytesMol Vis 15 (2009) 2084-2093Barbaro V, Ferrari S, Fasolo A, et alICC
Cytokeratin 14
2001-1
Correction of Laminin-5 Deficiency in Human Epidermal Stem Cells by Transcriptionally Targeted Lentiviral VectorsMol Ther 16 (2008) 1977-1985Di Nunzio F, Maruggi G, Ferrari S, et alIHC
Cytokeratin 15 (C-term)
1954-1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingivaOral Surg Oral Med Oral Pathol Oral Radiol Endod 109 (2010) e34-e39Mochizuki Y, Omura K, Sakamoto K, et alIHC
Cytokeratin 18
1433-1
Inhibition of Peroxisome Proliferator-Activated Receptor γ Increases Estrogen Receptor–Dependent Tumor SpecificationCancer Res 69 (2009) 687–694Yin YZ, Yuan HY, Zeng X, et alIHC
Cytokeratin 18
1924-1
Recovery of Multipotent Progenitors from the Peripheral Blood of Patients Requiring ECMO SupportAm J Respir Crit Care Med 181 (2010) 226-237Bui KC, Senadheera D, Wang X, et al
Cytokeratin 19 (C-term)
1968-1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingivaOral Surg Oral Med Oral Pathol Oral Radiol Endod 109 (2010) e34-e39Mochizuki Y, Omura K, Sakamoto K, et alIHC
Cytokeratin 4
1994-1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingivaOral Surg Oral Med Oral Pathol Oral Radiol Endod 109 (2010) e34-e39Mochizuki Y, Omura K, Sakamoto K, et alIHC
Cytokeratin 4
1994-1
Recovery of Multipotent Progenitors from the Peripheral Blood of Patients Requiring ECMO SupportAm J Respir Crit Care Med 181 (2010) 226-237Bui KC, Senadheera D, Wang X, et al
Cytokeratin 5 (C-term)
1988-1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingivaOral Surg Oral Med Oral Pathol Oral Radiol Endod 109 (2010) e34-e39Mochizuki Y, Omura K, Sakamoto K, et alIHC
DARPP-32
1710-1
Sex differences in a transgenic rat model of Huntington’s disease: decreased 17b-estradiol levels correlate with reduced numbers of DARPP321 neurons in malesHuman Molecular Genetics 17 (2008) 2595–2609Bode FJ, Stephan M, Suhling H, et alICC
Daxx
1094-1
Nuclear Domain 10 Components Promyelocytic Leukemia Protein and hDaxx Independently Contribute to an Intrinsic Antiviral Defense against Human Cytomegalovirus InfectionJournal of Virology 82 (2008) 126–137Tavalai N, Papior P, Rechter S, et alWB
Daxx
1094-1
The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML networkNature 455 (2008) 813-817Song MS, Salmena L, Carracedo A, et alWB
Daxx
1094-1
New insights into the role of the subnuclear structure ND10 for viral infectionBiochimica et Biophysica Acta (BBA) - Molecular Cell Research 1783 (2008) 2207-2221Tavalai N, Stamminger TWB
Daxx
1094-1
Mutations in the M112/M113 coding region facilitate murine cytomegalovirus replication in human cellsJ Virol 84 (2010) 7994-8006Schumacher U, Handke W, Jurak I, et al
Daxx
1094-1
Insertion of an EYFP-pp71 (UL82) Coding Sequence into the Human Cytomegalovirus Genome Results in a Recombinant Virus with Enhanced Viral GrowthJ Virol 82 (2008) 10543-10555Tavalai N, Kraiger M, Kaiser N, et alWB
Desmin
1466-1
Up-regulation of soluble vascular endothelial growth factor receptor-1 prevents angiogenesis in hypertrophied myocardiumCardiovasc Res 89 (2011) 410-418Kaza E, Ablasser K, Poutias D, et alIHC
Desmin
1466-1
C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodiaDevelopmental Biology 301 (2007) 70–81Yoon S, Molloy MJ, Wu MP, et alICC
Desmin
1466-1
Mutation in the key enzyme of siallic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamineJournal of Clinical Investigation 117 (2007) 1585-1594Galeano B, Klootwijk R, Manoli I, et alWB
Desmin
1466-1
Bone Marrow Cell Recruitment Mediated by Inducible Nitric Oxide Synthase/Stromal Cell-Derived Factor-1α Signaling Repairs the Acoustically Damaged Cochlear Blood-Labyrinth BarrierAm J Pathol 177 (2010) 3089-3099Dai M, Yang Y, Omelchenko I, et al
DUX4
5158-1
Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene.PLoS Genet. 2010 Oct 28;6(10):e1001181.Snider L, Geng LN, Lemmers RJ, Kyba M, Ware CB, Nelson AM, Tawil R, Filippova GN, van der Maarel SM, Tapscott SJ, Miller DG.WB
E-Cadherin
1702-1
Characterization of a novel type of adherens junction in meningiomas and the derived cell line HBL-52Cell Tissue Res 331 (2008) 401–412Akat K, Bleck CKE, Lee YMA, et alIP, ICC
E-Cadherin
1702-1
Overexpression of TGF-β1 in foetal monkey lung results in Prenatal Pulmonary FibrosisEur Respir J. 2010Tarantal AF, Chen H, Shi TT, et al
E-Cadherin
1702-1
A Molecular Clutch between the Actin Flow and N-Cadherin Adhesions Drives Growth Cone MigrationThe Journal of Neuroscience 28 (2008) 5879 –5890Bard L, Boscher C, Lambert M, et alICC
E-Cadherin
1702-1
Overexpression of transforming growth factor-β1 in fetal monkey lung results in prenatal pulmonary fibrosisEur Respir J 36 (2010) 907-914Tarantal AF, Chen H, Shi TT, et al
E-Cadherin
1702-1
Differential expression pattern of protein ARVCF in nephron segments of human and mouse kidneyHistochem Cell Biol 130 (2008) 943-956Walter B, Schlechter T, Hergt M, et alICC
E-Cadherin
1702-1
Evidence for Epithelial–Mesenchymal Transition in Adult Human Pancreatic Exocrine CellsJ Histochem Cytochem 58 (2010) 807-823Fanjul M, Gmyr V, Sengenès C, et al
E-Cadherin
1702-1
Side population cells in the mouse thyroid exhibit stem/progenitor celllike characteristicsEndocrinology 148 (2007) 4251 - 4258Hoshi N, Kusakabe T, Taylor BJ, et alICC
E-Cadherin
1702-1
Nodal Lymphangiogenesis and Metastasis: Role of Tumor-Induced Lymphatic Vessel Activation in Extramammary Paget’s DiseaseAm J Pathol 175 (2009) 2235-2248Hirakawa S, Detmar M, Kerjaschki D, et alIHC
E-Cadherin
1702-1
Homo- and Heterotypic Cell Contacts in Malignant Melanoma Cells and Desmoglein 2 as a Novel Solitary Surface GlycoproteinJournal of Investigative Dermatology 127 (2007) 2191–2206Schmitt CJ, Franke WW, Goerdt S, et alICC
E-Cadherin
1702-1
Protein p0071, an armadillo plaque protein of adherens junctions, is predominantly expressed in distal renal tubulesHistochem Cell Biol 133 (2010) 69-83Walter B, Krebs U, Berger I, et alICC
E-Cadherin
1702-1
Expression, purification, and functional characterization of recombinant PTD-SARAActa Biochim Biophys Sin (Shanghai) 43 (2011) 110-117Huang C, Du R, Zhang P, et al
EGFR
1114-1
Material hepatic growth response to pregnancy in the mouseExp Biol Med (Maywood). (2011) 236(11):1322-32 Guoli Dai, Juan J Bustamante, et al
EGFR Phospho (pY1068)
1138-1
Acrolein increases 5-lipoxygenase expression in murine macrophages through activation of ERK pathwayToxicol Appl Pharmacol 245 (2010) 76-82Kim CE, Lee SJ, Seo KW, et alWB
EGFR Phospho (pS1046/pS1047)
2221-1
The IL-8–Regulated Chemokine Receptor CXCR7 Stimulates EGFR Signaling to Promote Prostate Cancer GrowthCancer Res 71 (2011) 3268-3277Singh RK, Lokeshwar BL
EGFR Phospho (pY1068)
1727-1
Involvement of Epidermal Growth Factor Receptor-linked Signaling Responses in Pseudomonas fluorescens-infected Alveolar Epithelial CellsInfect Immun 79 (2011) 1998-2005Choi HJ, Seo CH, Park SH, et al
EGFR Phospho (pY1086)
1139-1
Perinatal increases in TGF- disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysisAm J Physiol Lung Cell Mol Physiol 293 (2007) L314-L327Kramer EL, Deutsch GH, Sartor MA, et alWB
EGFR Phospho (pY1173)
1124-1
Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumabOncogene 28 (2009) 461–468Pickl M, Ries CHWB
EGFR Phospho (pY1173)
1124-1
Epitope mapping of epidermal growth factor receptor (EGFR) in lung cancer using immunohistochemistry: Fine tuning the protocolsASCO Meeting Abstracts 25 (2007): 21162TIMAR J, Derecskei K, Dome B, et al
EGFR Phospho (pY1173)
1124-1
Multipathway Model Enables Prediction of Kinase Inhibitor Cross-Talk Effects on Migration of Her2-Overexpressing Mammary Epithelial CellsMol Pharmacol 73 (2008) 1668–1678Kumar N, Afeyan R, Kim HD, et alICC
EGFR Phospho (pY845)
2342-1
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changesBrain Res Bull 81 (2010) 262–272Saghizadeh M, Kramerov AA, Yaghoobzadeh Y, et al
EGFR Phospho (pY845)
2342-1
Normalization of Wound Healing and Diabetic Markers in Organ Cultured Human Diabetic Corneas by Adenoviral Delivery of c-Met GeneInvest Ophthalmol Vis Sci 51 (2010) 1970-1980Saghizadeh M, Kramerov AA, Yu FS, et al
eIF-2a Phospho (pS51)
1090-1
Amino acid limitation induces the GCN2 signaling pathway in myoblasts but not in myotubesBiochimie 90 (2008) 1716-1721Deval C, Talvas J, Chaveroux C, et alWB
eIF-2a Phospho (pS51)
1090-1
Inhibition of Golgi Apparatus Glycosylation Causes Endoplasmic Reticulum Stress and Decreased Protein SynthesisJ Biol Chem 285 (2010) 24600-24608Xu YX, Liu L, Caffaro CE, et al
eIF-2a Phospho (pS51)
1090-1
Translational Repression of MCL-1 Couples Stress-induced eIF2 Phosphorylation to Mitochondrial Apoptosis InitiationThe Journal of Biological Chemistry 282 (2007) 22551–22562Fritsch RM, Schneider G, Saur D, et alWB
eIF-2a Phospho (pS51)
1090-1
The effect of the vaccinia K1 protein on the PKR-eIF2α pathway in RK13 and HeLa cellsVirology 394 (2009) 73-81Willis KL, Patel S, Xiang Y, et alWB
eIF-2a Phospho (pS51)
1090-1
Sublethal Cadmium Intoxication In Arabidopsis thaliana Impacts Translation at Multiple LevelsPlant Cell Physiol 52 (2011) 436-447Sormani R, Delannoy E, Lageix S, et alWB
eIF-2a Phospho (pS51)
1090-1
Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cellsGut 59 (2010) 365-372Szmola R, Sahin-Tóth M
eIF-2a Phospho (pS51)
1090-1
A Phosphosite Screen Identifies Autocrine TGF-β-Driven Activation of Protein Kinase R as a Survival-Limiting Factor for EosinophilsThe Journal of Immunology 180 (2008) 4256–4264Goplen N, Gorska MM, Stafford SJ, et qalICC
eIF-2a Phospho (pS51)
1090-1
Arabidopsis eIF2α kinase GCN2 is essential for growth in stress conditions and is activated by woundingBMC Plant Biology 2008 8:134Lageix S, Lanet E, Pouch-Pélissier MN, et alWB
eIF-2a Phospho (pS51)
1090-1
Viral Double-stranded RNAs from Vaccinia Virus Early or Intermediate Gene Transcripts Possess PKR Activating Function, Resulting in NF-κB Activation, When the K1 Protein Is Absent or MutatedJ Biol Chem 286 (2011) 7765-7778Willis KL, Langland JO, Shisler JL
eIF-2a Phospho (pS51)
1090-1
Pegylated arginase I: a potential therapeutic approach in T-ALLBlood 115 (2010) 5214-5221Hernandez CP, Morrow K, Lopez-Barcons LA, et alWB
eIF-2a Phospho (pS51)
1090-1
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infectionAm J Physiol Lung Cell Mol Physiol 294 (2008) L1119-L1126Lawson WE, Crossno PF, Polosukhin VV, et alIHC
eIF-2a Phospho (pS51)
1090-1
Spinal cord injury induces endoplasmic reticulum stress with different cell-type dependent responseJournal of Neurochemistry 102 (2007) 1242–1255Penas C, Guzman MS, Verdu E, et alWB
eIF-2a Phospho (pS51)
1090-1
BiP Availability Distinguishes States of Homeostasis and Stress in the Endoplasmic Reticulum of Living CellsMol Biol Cell 21 (2010) 1909-1921Lai CW, Aronson DE, Snapp EL
eIF-2a Phospho (pS51)
1090-1
Hypoxic Regulation of Id-1 and Activation of the Unfolded Protein Response Are Aberrant in NeuroblastomaThe Journal of Biological Chemistry 282 (2007) 240–248Nemetski SM and Gardner LBWB
eIF-2a Phospho (pS51)
1090-1
Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant miceJ. Cell Biol. 184 (2009) 143 - 158Wang X, Rao RP, Kosakowska-Cholody T, et alWB
Elk-1
1277-1
Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machineryGenome Res 19 (2009) 1963-1973Boros J, Donaldson IJ, O'Donnell A, et alWB, ChIP
Elk-1
1277-1
Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family membersNucleic Acids Res 37 (2009) 7368-7380Boros J, O'Donnell A, Donaldson IJ, et alWB, ChIP
Elk-1
1277-1
Activation and Repression of Cellular Immediate Early Genes by Serum Response Factor CofactorsJ Biol Chem 285 (2010) 22036-22049Lee SM, Vasishtha M, Prywes R
Elk-1
1277-1
Rev7/MAD2B Links c-Jun N-Terminal Protein Kinase Pathway Signaling to Activation of the Transcription Factor Elk-1Molecular and Cellular Biology 27 (2007) 2861–2869Zhang L, Yang SH, and Sharrocks ADWB
EMTK/ITK/TSK (C-term)
1595-1
Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferationJ. Clin. Invest. 119 (2009) 1350-1358Huck K, Feyen O, Niehues T, et alWB
Epithelial Antigen (Ep-CAM)
1144-1
Epithelial Cell Adhesion Molecule Regulation Is Associated with the Maintenance of the Undifferentiated Phenotype of Human Embryonic Stem CellsJ Biol Chem 285 (2010) 8719-8732Lu TY, Lu RM, Liao MY, et al
Epithelial Antigen (Ep-CAM)
1144-1
Nuclear signalling by tumour-associated antigen EpCAMNature Cell Biology11 (2009) 162-171Maetzel D, Denzel S, Mack B, et alIP
Epithelial Antigen (Ep-CAM)
1144-1
EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosisBMC Cancer 10 (2010) 331Ralhan R, Cao J, Lim T, et al
Epithelial Antigen (Ep-CAM)
1144-1
The Epithelial Cell Adhesion Molecule EpCAM Is Required for Epithelial Morphogenesis and Integrity during Zebrafish Epiboly and Skin DevelopmentPLoS Genet 5 (2009) e1000563Slanchev K, Carney TJ, Stemmler MP, et alIHC
EpoR Phospho (pY485)
2585-1
Erythropoietin Receptor Signaling through STAT3 Is Required for Glioma Stem Cell MaintenanceGenes & Cancer 1 (2010) 50 - 61Cao Y, Lathia JD, Eyler CE, et alFACS
EPS15R
1857-1
Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virusProceedings of the National Academy of Sciences 105 (2008) 11790–11795Chen C, Zhuang XWICC
EPS15R
1857-1
A requirement for epsin in mitotic membrane and spindle organizationJ. Cell Biol. 186 (2009) 473 - 480Liu ZH, Zheng YXWB
ER alpha Phospho (pS118)
1091-1
Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine ResistanceClin Cancer Res 16 (2010) 1486-1497Leary AF, Drury S, Detre S, et al
ERBB4(v-erb-A) antibody
S2236
LH-Induced Neuregulin 1 (NRG1) Type III Transcripts Control Granulosa Cell Differentiation and Oocyte MaturationMol Endocrinol 25 (2011)104-116Noma N, Kawashima I, Fan HY, et al
ERG
2805-1
Antibody-based detection of ERG rearrangement-positive prostate cancerNeoplasia. 2010 Jul;12(7):590-8Park K, Tomlins SA, Mudaliar KM, et al.IHC
ERG
2805-1
Antibody EPR3864 is specific for ERG genomic fusions in prostate cancer: implications for pathological practice.Mod Pathol. 2011van Leenders GJ, Boormans JL, et al
Erk1 (pT202)/Erk2 (pT185) Phospho
1481-1
Possible Relevance between Prohormone Convertase 2 Expression and Tumor Growth in Human Adrenocorticotropin-Producing Pituitary AdenomaJ Clin Endocrinol Metab 95 (2010) 4003-4011Iino K, Oki Y, Yamashita M, et al
Erk3/MAPK6
2030-1
Activation Loop Phosphorylation of ERK3/ERK4 by Group I p21-activated Kinases (PAKs) Defines a Novel PAK-ERK3/4-MAPK-activated Protein Kinase 5 Signaling PathwayJ Biol Chem 286 (2011) 6470-6478Déléris P, Trost M, Topisirovic I, et al
ERRalpha antibody
S0624
Extracellular Signal-regulated Kinase 8 (ERK8) Controls Estrogen-related Receptor α (ERRα) Cellular Localization and Inhibits Its Transcriptional ActivityJ Biol Chem 286 (2011) 8507-8522Rossi M, Colecchia D, Iavarone C, et alWB
Ezrin
2255-1
MicroRNA-183 regulates Ezrin expression in lung cancer cellsFEBS Letters 582 (2008) 3663-3668Wang GF, Mao WM, Zheng SWB
Ezrin
2255-1
Participation of ezrin in bacterial uptake by trophoblast giant cellsReprod Biol Endocrinol (2009) 7:95Watanabe K, Tachibana M, Kim S, et alWB, ICC
Ezrin
1729-1
MicroRNA-183 regulates Ezrin expression in lung cancer cellsFEBS Letters 582 (2008) 3663-3668Wang GF, Mao WM, Zheng SWB
Ezrin
1729-1
Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19qNeuro Oncol 12 (2010) 243-256Grzendowski M, Wolter M, Riemenschneider MJ, et alWB
Ezrin
1729-1
Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19qNeuro Oncol 12 (2010) 243-256Grzendowski M, Wolter M, Riemenschneider MJ, et alWB
FADD (N-term)
1825-1
Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesisAm J Physiol Gastrointest Liver Physiol 296 (2009) G850-G859Onizawa M, Nagaishi T, Kanai T, et alWB
FAK
1700-1
Expression of Src and FAK in Hepatocellular Carcinoma and the Effect of Src Inhibitors on Hepatocellular Carcinoma In VitroDig Dis Sci. 54 (2009) 1465-1474Lau GM, Lau GM, Yu GL, et alIHC
FAK Phospho (pY397)
2211-1
Tuberin Regulates E-Cadherin Localization: Implications in Epithelial-Mesenchymal TransitionAm J Pathol 177 (2010) 1765-1778Barnes EA, Kenerson HL, Jiang X, et al
FAK Phospho (pY576)
2103-1
Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1Exp Cell Res 316 (2010) 138-148Strell C, Lang K, Niggemann B, et alWB
FAK Phospho (pY576/577)
2183-1
Leptin stimulates the migration of colon carcinoma cells by multiple signaling pathwaysEndocr Relat Cancer 17 (2010) 179-189Ratke J, Entschladen F, Niggemann B, et alWB
FAK2/Pyk2 (N-term)
1509-1
Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1rPNAS 106 (2009) 1802 - 1807Pape EL, Passeron T, Giubellino A, et alWB
Fc gamma RIIb
1787-1
Peripheral Formalin Injection Induces Unique Spinal Cord Microglial Phenotypic ChangesNeuroscience Letters 449 (2009) 234-239Fu KY, Tan YH, Sung B, et alIHC
Fc gamma RIIb
1787-1
Helicobacter pylori eradication shifts monocyte Fcγ receptor balance toward inhibitory FcγRIIB in immune thrombocytopenic purpura patientsJ. Clin. Invest 118 (2008) 2939–2949Asahi A, Nishimoto T, Okazaki Y, et alICC
Fc gamma RIIb/CD32 Phospho (pY292)
2308-1
Antibody-Mediated Coengagement of FcγRIIb and B Cell Receptor Complex Suppresses Humoral Immunity in Systemic Lupus ErythematosusJ Immunol 186 (2011) 4223-4233Horton HM, Chu SY, Ortiz EC, et al
FGF Receptor 1
2144-1
Altered Splicing of FGFR1 Is Associated with High Tumor Grade and Stage and Leads to Increased Sensitivity to FGF1 in Bladder CancerAm J Pathol 177 (2010) 2379-2386Tomlinson DC, Knowles MA
Filamin A (C-term)
2242-1
Pro-prion Binds Filamin A, Facilitating Its Interaction with Integrin β1, and Contributes to MelanomagenesisJ Biol Chem 285 (2010) 30328-30339Li C, Yu S, Nakamura F, et al
FOXO3a
2071-1
Protection against Glucocorticoid-Induced Damage in Human Tenocytes by Modulation of ERK, Akt, and Forkhead SignalingEndocrinology 152 (2011) 503-514Poulsen RC, Carr AJ, Hulley PA
FOXO3a
2071-1
Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatinCancer Sci 101 (2010) 1177–1185Shiota M, Yokomizo A, Kashiwagi E, et alWB
Fyn (p59Fyn)
1562-1
Epidermal hyperplasia and papillomatosis in mice with a keratinocyte-restricted deletion of cskCarcinogenesis 28 (2007) 2074–2081HondaK, Sakaguchi T, Sakai K,et al
GAPDH
2251-1
microRNA-92a Promotes Lymph Node Metastasis of Human Esophageal Squamous Cell Carcinoma via E-CadherinJ Biol Chem 286 (2011) 10725-10734Chen ZL, Zhao XH, Wang JW, et al
GAPDH
2251-1
A Novel Mouse Model for De novo MelanomaCancer Res 70 (2010) 24-29Kumasaka MY, Yajima I, Hossain K, et alWB
GAPDH
2251-1
A Novel Mouse Model for De novo MelanomaCancer Res 70 (2010) 24-29Kumasaka MY, Yajima I, Hossain K, et alWB
GARS Antibody (C-term)
T2874
The Survival of Motor Neuron (SMN) Protein Interacts with the mRNA-Binding Protein HuD and Regulates Localization of Poly(A) mRNA in Primary Motor Neuron AxonsJ Neurosci 31 (2011) 3914-3925Fallini C, Zhang H, Su Y, et al
GFP
1533-1
Cell-to-cell trafficking, subcellular distribution, and binding to coat protein of Broad bean wilt virus 2 VP37 proteinVirus Res 143 (2009) 86-93Liu CK, Meng CM, Xie L, et alWB
GFP
1533-1
OB Fold-containing Protein 1 (OBFC1), a Human Homolog of Yeast Stn1, Associates with TPP1 and Is Implicated in Telomere Length RegulationJ Biol Chem. 284 (2009) 26725-26731Wan M, Qin J, Songyang Z, et alWB
GFP
1533-1
Live-Cell Imaging in Caenorhabditis elegans Reveals the Distinct Roles of Dynamin Self-Assembly and Guanosine Triphosphate Hydrolysis in the Removal of Apoptotic CellsMol Biol Cell 21 (2010) 610-629He B, Yu X, Margolis M, et al
GFP
1533-1
Characterization and subcellular localization of an RNA silencing suppressor encoded by Rice stripe tenuivirusVirology 387 (2009) 29-40Xiong RY, Wu JX, Zhou YJ, et alWB
GFP
1533-1
The TCR's α-CPM promotes close approximation of the CD8 coreceptor allowing efficient signal initiationJ Immunol 180 (2008) 8211-8221Mallaun M, Naeher D, Daniels MA, et alIP
GFP
1533-1
Depletion of the MobB and CotA complex in Aspergillus nidulans causes defects in polarity maintenance that can be suppressed by the environment stressFungal Genetics and Biology 45 (2008) 1570–1581Shi J, Chen WW, Liu Q, et alWB
GFP
1533-1
Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptorVirology 397 (2010) 369-378Choi YB, Nicholas JWB, ICC
GFP
1533-1
The T Cell Receptor’s -Chain Connecting Peptide Motif Promotes Close Approximation of the CD8 Coreceptor Allowing Efficient Signal InitiationThe Journal of Immunology 180 (2008) 8211–8221Mallaun M, Naeher D, Daniels MA, et alIP
GFP
1533-1
Localization and function of calmodulin in live-cells of Aspergillus nidulansFungal Genet Biol 47 (2010) 268-278Chen S, Song Y, Cao J, et alWB
GluR1
1326-1
SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensationJ. Cell Sci. 122 (2009) 2946 - 2956Kinkley S, Staege H, Mohrmann G, et al
GluR1
1326-1
Overexpression of CD97 in Intestinal Epithelial Cells of Transgenic Mice Attenuates Colitis by Strengthening Adherens JunctionsPLoS One 5 (2010) e8507Becker S, Wandel E, Wobus M, et alWB
GluR1
1326-1
Epigenetic modifications induced by RGC-32 in colon cancerExp Mol Pathol 88 (2010) 67-76Vlaicu SI, Tegla CA, Cudrici CD, et alWB
GluR1
1308-1
Attenuated AMPA Receptor Expression Allows Glioblastoma Cell Survival in Glutamate-Rich EnvironmentPLoS One. 4 (2009) e5953van Vuurden DG, Yazdani M, Bosma I, et alIHC
GluR1
1326-1
Chromatin Environment of Histone Variant H3.3 Revealed by Quantitative Imaging and Genome-scale Chromatin and DNA ImmunoprecipitationMol Biol Cell 21 (2010) 1872-1884Delbarre E, Jacobsen BM, Reiner AH, et al
GluR2/3
1905-1
Duplicated Gephyrin Genes Showing Distinct Tissue Distribution and Alternative Splicing Patterns Mediate Molybdenum Cofactor Biosynthesis, Glycine Receptor Clustering, and Escape Behavior in ZebrafishJ Biol Chem 286 (2011) 806-817Ogino K, Ramsden SL, Keib N, et al
GSK3 alpha/beta
2199-1
Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodentsCancer Sci 98 (2007) 1388–1393Shakoori A, Mai W, Miyashita K, et alIHC
H-Ras (C-term)
1521-1
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence responseProceedings of the National Academy of Sciences 105 (2008) 5402–5407Swarbrick A, Roy E, Allen T, et alWB
H-Ras (C-term)
1521-1
Ras signaling directs endothelial specifi cation of VEGFR2 + vascular progenitor cellsThe Journal of Cell Biology 181 (2008) 131–141Kawasaki K, Watabe T, Sase H, et alIHC
HER2 / ErbB2
2064-1
Silencing of ErbB3/ErbB2 Signaling by Immunoglobulin-like Necl-2J. Biol. Chem. 284 (2009) 23793 - 23805Kawano S, Ikeda W, Kishimoto M, et alIP
HIAP-1 / BIR3
1040-1
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2–mediated resistanceBlood 113 (2009) 1710 - 1722Fakler M, Loeder S, Vogler M, et al
HIAP-1 / BIR3
1040-1
Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8Oncogene 28 (2009) 3097–3110Häcker S, Dittrich A, Mohr A, et alWB
HIAP-1 / BIR3
1040-1
A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic LeukemiaCancer Res. 69 (2009) 8977 - 8986Loeder S, Zenz T, Schnaiter A, et al
HIAP-1 / BIR3
1040-1
Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytesBlood 107 (2006) 4491-4499Waldele K, Silbermann K, Schneider G, et alWB
Histone Deacetylase 2
1603-1
Epigenetic modifications induced by RGC-32 in colon cancerExp Mol Pathol 88 (2010) 67-76Vlaicu SI, Tegla CA, Cudrici CD, et alWB
Histone Deacetylase 3
1580-1
Large-cell neuroendocrine carcinoma of the ampulla of VaterMed Oncol 27 (2010) 1144-1148Stojsic Z, Brasanac D, Bilanovic D, et alIHC
Histone H2A.x Phospho (pS139)
2212-1
DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate TissueCancer Res 70 (2010) 8630-8641Jäämaa S, Af Hällström TM, Sankila A, et al
Histone H2A.x Phospho (pS139)
2212-1
Angiotensin II Induces DNA Damage in the KidneyCancer Res 68 (2008) 9239-9246Schmid U, Stopper H, Schweda F, et alICC
Histone H2A.x Phospho (pS139)
2212-1
High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genomeEMBO J 29 (2010) 1446-1457Iacovoni JS, Caron P, Lassadi I, et alICC, ChIP
Histone H2B Acetyl (K15)
2170-1
Epigenetic modifications induced by RGC-32 in colon cancerExp Mol Pathol 88 (2010) 67-76Vlaicu SI, Tegla CA, Cudrici CD, et alWB
Histone H3 Acetyl (K18)
1766-1
Epigenetic modifications induced by RGC-32 in colon cancerExp Mol Pathol 88 (2010) 67-76Vlaicu SI, Tegla CA, Cudrici CD, et alWB
Histone H3 Acetyl (K56)
2134-1
CBP/p300-mediated acetylation of histone H3 on lysine 56Nature 459 ( 2009) 113-117Das C, Lucia MS, Hansen KC, et alWB, FC
Histone H3 Acetyl (K56)
2134-1
Regulation of Angiogenesis by Histone Chaperone HIRA-mediated Incorporation of Lysine 56-acetylated Histone H3.3 at Chromatin Domains of Endothelial GenesJ Biol Chem 285 (2010) 41567-41577Dutta D, Ray S, Home P, et al
Histone H3 Acetyl (K56)
2134-1
Systematic in vivo structure-function analysis of p300 in hematopoiesisBlood 114 (2009) 4804 - 4812Kimbrel EA, Lemieux ME, Xia X, et al
Histone H3 Acetyl (K56)
2134-1
Histone H3 Lysine 56 Acetylation Is Linked to the Core Transcriptional Network in Human Embryonic Stem CellsMolecular Cell 33 (2009) 417-427Xie W, Song CY, Young NL, et alWB
Histone H3 Acetyl (K56)
2134-1
Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localizationMech Ageing Dev 131 (2010) 185-192Tennen RI, Berber E, Chua KFWB
Histone H3 Acetyl (K56)
2134-1
HIS-24 Linker Histone and SIR-2.1 Deacetylase Induce H3K27me3 in the Caenorhabditis elegans Germ LineMol. Cell. Biol. 29 (2009) 3700 - 3709Wirth M, Paap F, Fischle W, et al
Histone H3 Acetyl (K56)
2134-1
Linker histone HIS-24 and SIR-2.1 deacetylase induce H3K27me3 in C. elegans germlineMol. Cell. Biol. 29 (2009) 3700-3709Wirth M, Paap F, Fischle W, et alICC
Histone H3 Dimethyl (K4)
1347-1
Structural Basis for the Specific Recognition of Methylated Histone H3 Lysine 4 by the WD-40 Protein WDR5Molecular Cell 22 (2006) 137-144Han ZF, Guo L, Wang HY, et al
Histone H3 Phospho (pS10)
1173-1
RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in DrosophilaDevelopment 135 (2008) 2917-2925Cai WL, Bao XM, Deng H, et alIHC
Histone H3 Phospho (pS10)
1173-1
Cotreatment with Vorinostat Enhances Activity of MK-0457 (VX-680) against Acute and Chronic Myelogenous Leukemia CellsClin Cancer Res. 14 (2008) 6106-6115Fiskus W, Wang Y, Joshi R, et alWB
Histone H3 Phospho (pS10)
1173-1
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78Blood 117 (2011) 1270-1279Roué G, Pérez-Galán P, Mozos A, et al
Histone H3 Phospho (pS10)
1173-1
Co-treatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cellsClin Cancer Res. 14 (2008) 6106-6115Fiskus W, Wang Y, Joshi R, et alWB
Histone H3 Phospho (pS10)
1173-1
Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in DrosophilaDevelopment 135 (2008) 699-705Deng HA, Bao XM, Cai WL, et alIHC
Histone H3 Phospho (pS10)
1173-1
Immunohistochemical Assesment of Mitotic Index in Uveal MelanomaInvest. Ophthalmol. Vis. Sci. 50 (2009) :6180Angi M, Damato B, Taktak AFG, et alIHC
Histone H3 Phospho (pS10)
1173-1
Prognostic Significance of the Mitotic Index Using the Mitosis Marker Anti–Phosphohistone H3 in MeningiomasAm J Clin Pathol 128 (2007) 118 - 125Kim YJ, Ketter R, Steudel WI, et al
HSD17B1
2002-1
Increased intratumoral androgens in human breast carcinoma following aromatase inhibitor exemestane treatmentEndocr Relat Cancer 17 (2010) 415-430Takagi K, Miki Y, Nagasaki S, et alIHC
HSF1
2043-1
Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysisCancer Immunol Immunother 58 (2009) 1275-1285Zhang C, Wang Y, Zhou Z, et alWB
HSP27 Phospho (pS82)
1118-1
Phosphoproteome Study Reveals Hsp27 as a Novel Signaling Molecule Involved in GDNF-Induced Neurite OutgrowthJ. Proteome Res. 8 (2009) 2768–2787Hong Z, Zhang QY, Liu J, et alWB
HSP27 Phospho (pS82)
1118-1
Biological Significance of Decreased HSP27 in Human AtherosclerosisArterioscler Thromb Vasc Biol 26 (2006) 1337-1343Martin-Ventura JL, Nicolas V, Houard X, et alWB
HSP27 Phospho (pS82)
1118-1
Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosisRespir Res 7 (2006) :95Chilosi M, Zamò A, Doglioni C, et alIHC
HSP47
3198-1
CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarctionAm J Physiol Heart Circ Physiol 300 (2011) H1418-H1426Zamilpa R, Kanakia R, Cigarroa J 4th, et alWB
HSP60
1724-1
Lindane and cell death: At the crossroads between apoptosis, necrosis and autophagyToxicology 256 (2009) 32-41Zucchini-Pascal N, Sousa G, Rahmani RWB
HSP70
1776-1
Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysisCancer Immunol Immunother 58 (2009) 1275-1285Zhang C, Wang Y, Zhou Z, et alWB
HSP90 beta
1492-1
Proteomic and Functional Analyses Reveal a Dual Molecular Mechanism Underlying Arsenic-Induced Apoptosis in Human Multiple Myeloma CellsJ. Proteome Res. 8 (2009) 3006–3019Ge F, Lu XP, Zeng HL, et alWB
hTERT
1531-1
Telomerase directly regulates NF-κB-dependent transcriptionNature Cell BiologyGhosh A, et al.IP, WB
hTERT
1531-1
Suppression of hPOT1 in Diploid Human Cells Results in an hTERT-Dependent Alteration of Telomere Length DynamicsMol Cancer Res 6 (2008) 1582-1593Possemato R, Timmons JC, Bauerlein EL, et alWB
hTERT
1531-1
Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From DamageArterioscler Thromb Vasc Biol. 29 (2009) 929-935Haendeler J, Dröse S, Büchner N, Jakob S, et alWB
hTERT
1531-1
Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell linesCancer Sci 99 (2008) 280 –286Mitomo S, Maesawa C, Ogasawara S, et alWB
hTERT
1531-1
A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunctionAging Cell 9 (2010) 203-219Kovalenko OA, Caron MJ, Ulema P, et alWB
hTERT
1531-1
Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2J Dig Dis 11 (2010) 176-184Zhong YQ, Xia ZS, Fu YR, et alWB
Huntingtin Protein (Htt)
1756-1
Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington diseaseNeuroscience 163 (2009) 1128-1134Cho KJ, Lee BI, Cheon SY, et alIHC, WB
Huntingtin Protein (Htt)
1756-1
Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseasesBrain 133 (2010) 2920-2941Clemen CS, Tangavelou K, Strucksberg KH, et al
IDO
2121-1
Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous diseaseBlood 116 (2010) 1755-1760De Ravin SS, Zarember KA, Long-Priel D, et al
IFN gamma
1833-1
Vibrio parahaemolyticus elevates interferon alpha production in intestinal-like epithelial Caco-2 cellsCan. J. Microbiol. 53 (2007) 1084–1090Lian X, Takahashi A, Nakano M, et alWB
IKK alpha
1615-1
Hepatic NF-kB essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesisProceedings of the National Academy of Sciences 105 (2008) 1297–1302Wunderlich FT, Luedde T, Singer S, et alWB
IKK beta
1601-1
IKKβ Mediates Cell Shape-Induced Aromatase Expression and Estrogen Biosynthesis in Adipose Stromal CellsMol Endocrinol 23 (2009) 662-670Ghosh S, Choudary A, Ghosh S, et alWB
IKK beta
1601-1
Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant SubjectsDiabetes 57 (2008) 2595 - 2602Reyna SM, Ghosh S, Tantiwong P, et alIP
IL-1R1
1695-1
IL-6 and IL-1 synergistically enhanced the production of MMPs from synovial cells by up-regulating IL-6 production and IL-1 receptor I expressionCytokine 51 (2010) 178-183Suzuki M, Hashizume M, Yoshida H, et alWB
IL-3R beta
1850-1
Human Basophils Secrete IL-3: Evidence of Autocrine Priming for Phenotypic and Functional Responses in Allergic DiseaseThe Journal of Immunology 182 (2009) 2432-2438Schroeder JT, Chichester KL, Bieneman AP
IL-8
1856-1
Unique Early Gene Expression Patterns in Human Adult-to-Adult Living Donor Liver Grafts Compared to Deceased Donor GraftsAmerican Journal of Transplantation 9 (2009) 758–772de Jonge J, Kurian S, Shaked A, et alIHC
ILK
1979-1
Integrin-linked Kinase Interactions with ELMO2 Modulate Cell PolarityMol. Biol. Cell 20 (2009) 3033 - 3043Ho E, Irvine T, Vilk GJA, et al
ILK
1979–1
Integrin-linked Kinase Interactions with ELMO2 Modulate Cell PolarityMol Biol Cell 20 (2009) 3033-3043Ho E, Irvine T, Vilk GJ, et alWB, IP
Integrin beta-3 (CD61 antigen)
2677-1
Cell Motility and Spreading Are Suppressed by HOXA4 in Ovarian Cancer Cells: Possible Involvement of β1 IntegrinMol. Cancer Res. 7 (2009) 1425 - 1437Klausen C, Leung PCK, Auersperg N
IRF3 Phospho (pS386)
2562-1
PIASy Inhibits Virus-induced and Interferon-stimulated Transcription through Distinct MechanismsJ Biol Chem 286 (2011) 8165-8175Kubota T, Matsuoka M, Xu S, et al
IRS-1
1692-1
Antisense treatment of IGF-IR enhances chemosensitivity in squamous cell carcinomas of the head and neckEur J Cancer 46 (2010) 1744-1751Liu S, Jin F, Dai W, et alWB
IRS-1 Phospho (pY896)
1813-1
Antisense treatment of IGF-IR enhances chemosensitivity in squamous cell carcinomas of the head and neckEur J Cancer 46 (2010) 1744-1751Liu S, Jin F, Dai W, et alWB
IRS-1 Phospho (pY896)
1813-1
The Reciprocal Regulation of γ- Synuclein and IGF-I Receptor Expression Creates a Circuit That Modulates IGF-I SignalingJ Biol Chem 285 (2010) 30480-30488Li M, Yin Y, Hua H, et al
JNK1 (pY185) / JNK2 (pY185) /JNK3 (pY223) Phospho
2155-1
PDZRN3 Negatively Regulates BMP-2–induced Osteoblast Differentiation through Inhibition of Wnt SignalingMol Biol Cell 21(2010) 3269-3277Honda T, Yamamoto H, Ishii A, et al
JNK1 (pY185) / JNK2 (pY185) /JNK3 (pY223) Phospho
2155-1
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMol. Cell. Biol. 29 (2009) 6515 - 6526Chaveroux C, Jousse C, Cherasse Y, et al
JNK2
2037-1
Cerebral ischemia provokes a profound exchange of activated JNK isoforms in brain mitochondriaMol Cell Neurosci 41 (2009) 186-195Zhao Y, Herdegen TWB, IP
JNK2
2037-1
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMol. Cell. Biol. 29 (2009) 6515 - 6526Chaveroux C, Jousse C, Cherasse Y, et al
Ki-67
4203-1
Stress-induced Senescence Exaggerates Post Injury Neointimal Formation in the Old VasculatureAm J Physiol Heart Circ Physiol 298 (2010) H66-74Khan SJ, Pham SM, Wei Y, et al
Ki-67
4203-1
Expanded CD23+/CD21hi B Cells in Inflamed Lymph Nodes Are Associated with the Onset of Inflammatory-Erosive Arthritis in TNF-Transgenic Mice and Are Targets of Anti-CD20 TherapyJ Immunol 184 (2010) 6142-6150Li J, Kuzin I, Moshkani S, et al
Ki-67
4203-1
Stress-induced senescence exaggerates postinjury neointimal formation in the old vasculatureAm J Physiol Heart Circ Physiol 298 (2010) H66-H74Khan SJ, Pham S, Wei Y, et al
Ki-67
4203-1
LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivoAm J Physiol Endocrinol Metab 298 (2010) E1261-E1273Sun G, Tarasov AI, McGinty JA, et al
Ki-67
4203-1
Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivoGut 57 (2008) 799 - 806Brockschmidt C, Hirner H, Huber N, et alIHC
Ki-67
4203-1
Prostasin regulates human placental trophoblast cell proliferation via the epidermal growth factor receptor signaling pathwayHum Reprod 25 (2010) 623-632Fu YY, Gao WL, Chen M, et alICC
Ki-67
4203-1
Enhanced tumorigenesis of forestomach tumors induced by N-Methyl-N¢-nitro-N-nitrosoguanidine in rats with hypoinsulinemic diabetesCancer Sci 101 (2010) 1604-1609Kodama Y, Ozaki K, Sano T, et alIHC
Ki-67
4203-1
Loss of Cystic Fibrosis Transmembrane Conductance Regulator Function Produces Abnormalities in Tracheal Development in Neonatal Pigs and Young ChildrenAm J Respir Crit Care Med 182 (2010) 1251-1261Meyerholz DK, Stoltz DA, Namati E, et al
Ki-67
4203-1
Environmental Enrichment Counteracts Alzheimer’s Neurovascular Dysfunction in TgCRND8 MiceBrain Pathology 18 (2008) 32–39Herring A, Yasin H, Ambree O, et alIHC (4203-1), WB (1303-1)
Ki-67
4203-1
Efficacy of PHA-848125, a Cyclin-Dependent Kinase Inhibitor, on the K-RasG12DLA2 Lung Adenocarcinoma Transgenic Mouse Model: Evaluation by Multimodality ImagingMol Cancer Ther 9 (2010) 673-681Degrassi A, Russo M, Nanni C, et al
Kv4.2
1834-1
Expression and localization of voltage dependent potassium channel Kv4.2 in epilepsy associated focal lesionsNeurobiol Dis.36 (2009) 81-95Aronica E, Boer K, Doorn KJ, et alIHC
Kv4.2
1834-1
Expression and localization of voltage dependent potassium channel Kv4.2 in epilepsy associated focal lesionsNeurobiol Dis. 36 (2009) 81-95Aronica E, Boer K, Doorn KJ, et alWB or ICC
Lamin B Receptor
1398-1
Cytomegaloviral proteins that associate with the nuclear lamina: components of a postulated nuclear egress complexJournal of General Virology 90 (2009) 579-590Milbradt J, Auerochs S, Sticht H, et alWB
Lamin B Receptor
1398-1
Induction of a Massive Endoplasmic Reticulum and Perinuclear Space Expansion by Expression of Lamin B Receptor Mutants and the Related Sterol Reductases TM7SF2 and DHCR7Mol Biol Cell 21 (2010) 354-368Zwerger M, Kolb T, Richter K, et al
Lamin B Receptor
1398-1
Histone Acetyltransferase hALP and Nuclear Membrane Protein hsSUN1 Function in De-condensation of Mitotic ChromosomesThe Journal of Biological Chemistry 282 (2007) 27447–27458Chi YH, Haller K, Peloponese JM, et alICC
Lamin B Receptor
1398-1
Induction of a Massive Endoplasmic Reticulum and Perinuclear Space Expansion by Expression of Lamin B Receptor Mutants and the Related Sterol Reductases TM7SF2 and DHCR7Mol Biol Cell 21 (2010) 354-368Zwerger M, Kolb T, Richter K, et al
Lamin B Receptor
1398-1
The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphologyFEBS Letters 580 (2006) 6435–6441Ulbert S, Antonin W, Platani M, et alICC
Lamin B Receptor
1398-1
Localization of Pom121 to the inner nuclear membrane is required for an early step of interphase nuclear pore complex assemblyMol Biol Cell 22 (2011) 1058-1069Funakoshi T, Clever M, Watanabe A, et alWB
Lamin B Receptor
1398-1
Novel cell death program leads to neutrophil extracellular trapsThe Journal of Cell Biology 176 (2007) 231–241Fuchs TA, Abed U, Goosmann C, et alTEM
Lamin B Receptor
1398-1
Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartmentMol. Biol. Cell 19 (2008) 5398 - 5408Barrowman J, Hamblet C, George CM, et alICC
Lamin B Receptor
1398-1
Cell-cycle-dependent dynamics of nuclear pores: pore-free islands and laminsJournal of Cell Science 119 (2006) 4442-4451Maeshima K, Yahata K, Sasaki Y, et alICC
Lamin B Receptor
1398-1
Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardiaJ Mol Med 86 (2008) 281–289Geiger SK, Bär H, Ehlermann P, et alICC
LAT Phospho (pY191)
1225-1
Formation of a Mast Cell Synapse: FcRI Membrane Dynamics upon Binding Mobile or Immobilized Ligands on SurfacesJ Immunol 184 (2010) 1328-1338Carroll-Portillo A, Spendier K, Pfeiffer J, et alICC
LAT Phospho (pY200)
2274-1
Lipid Raft Assembly and Lck Recruitment in TRAIL Costimulation Mediates NF-κB Activation and T Cell ProliferationJ Immunol 186 (2011) 931-939Huang SC, Tsai HF, Tzeng HT, et al
LCAT
2013-1
The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteumReproduction 139 (2010) 163-176Bogan RL, Hennebold JD
LCAT
2013-1
The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteumReproduction 139 (2010) 163-176Bogan RL, Hennebold JDIHC
LDH-A (muscle subunit)
2468-1
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progressionProc Natl Acad Sci U S A 107 (2010) 2037-2042Le A, Cooper CR, Gouw AM, et alWB
LDH-A (muscle subunit)
2468-1
Hyperpolarized 13C Spectroscopic Imaging Informs on Hypoxia-Inducible Factor-1 and Myc Activity Downstream of Platelet-Derived Growth Factor ReceptorCancer Res 70 (2010) 7400-7410Dafni H, Larson PE, Hu S, et al
LDL Receptor (C-term)
1956-1
The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteumReproduction 139 (2010) 163-176Bogan RL, Hennebold JDWB
LFA-1a/ITGAL/CD11a
1904-1
Clinical significance of co-expression of CD21 and LFA-1 in B-cell lymphomaInt J Hematol 89 (2009) 497-507Tanimoto K, Yakushijin Y, Fujiwara H, et alIHC
LFA-1a/ITGAL/CD11a
1904-1
Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil ActivationJ Biol Chem 286 (2011) 7070-7081Jerke U, Rolle S, Dittmar G, et al
Lyn
1619-1
Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signalingFree Radic Biol Med 48 (2010) 1133-1143Lee EJ, Jeon MS, Kim BD, et alWB
Lyn Phospho (pY396)
1645-1
Dasatinib Inhibits the Growth of Molecularly Heterogeneous Myeloid LeukemiasClin Cancer Res 16 (2010) 1149-1158Guerrouahen BS, Futami M, Vaklavas C, et al
Lyn Phospho (pY396)
1645-1
Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowthJ. Cell Sci. 122 (2009) 289 - 299Ichikawa N, Iwabuchi K, Kurihara H, et alWB
Lyn Phospho (pY396)
1645-1
Cdk-Inhibitory Activity and Stability of p27Kip1 Are Directly Regulated by Oncogenic Tyrosine KinasesCell 128 (2007) 269-280Grimmler M, Wang YF, Mund T, et alIP
Lyn Phospho (pY396)
1645-1
Therapeutic implications of Src independent calcium mobilization in diffuse large B-cell lymphomaLeuk Res 34 (2010) 585-593Hollmann CA, Tzankov A, Martínez-Marignac VL, et alWB
Lyn Phospho (pY396)
1645-1
Mechanisms of STAT Protein Activation by Oncogenic KIT Mutants in Neoplastic Mast CellsJ Biol Chem 286 (2011) 5956-5966Chaix A, Lopez S, Voisset E, et al
Lyn Phospho (pY396)
1645-1
The lectin Jacalin induces human B-lymphocyte apoptosis through glycosylation-dependent interaction with CD45Immunology 127 (2009) 477-488Ma BY, Yoshida K, Baba M, et alWB
Lyn Phospho (pY396)
1645-1
Targets and effectors of the cellular response to aurora kinase inhibitor MK-0457 (VX-680) in imatinib sensitive and resistant chronic myelogenous leukemiaBiochem Pharmacol 79 (2010) 688-697Donato NJ, Fang D, Sun H, et alWB
Lyn Phospho (pY396)
1645-1
Activities of SYK and PLC2 Predict Apoptotic Response of CLL Cells to SRC Tyrosine Kinase Inhibitor DasatinibClin Cancer Res 16 (2010) 587 - 599Song Z, Lu P, Furman RR, et al
Lyn Phospho (pY396)
1645-1
Protein purification and preliminary crystallographic analysis of human Lyn tyrosine kinaseProtein Expression and Purification 58 (2008) 318–324Kinoshita T,Miyano N,Nakai R, et alWB
Lyn Phospho (pY507)
1659-1
Opposite expression pattern of Src kinase Lyn in acute and chronic haematological malignanciesAnn Hematol 88 (2009) 1059-1067Hussein K, von Neuhoff N, Büsche G, et alIHC
Lyn Phospho (pY507)
1659-1
Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signalingFree Radic Biol Med 48 (2010) 1133-1143Lee EJ, Jeon MS, Kim BD, et alWB
Lyn Phospho (pY507)
1659-1
Protein purification and preliminary crystallographic analysis of human Lyn tyrosine kinaseProtein Expression and Purification 58 (2008) 318–324Kinoshita T,Miyano N,Nakai R, et alWB
Lyn Phospho (pY507)
1659-1
SH2 Domain-Containing Phosphatase-2 Protein-Tyrosine Phosphatase Promotes FcRI-Induced Activation of Fyn and Erk Pathways Leading to TNF Release from Bone Marrow-Derived Mast CellsJ. Immunol. 183 (2009) 4940 - 4947McPherson VA, Sharma N, Everingham S, et al
MALT1 / MLT1 (N-term)
1664-1
Gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma identifies new biologic insights with potential diagnostic and therapeutic applicationsBlood 113 (2009) 635 - 645Chng WJ, Remstein ED, Fonseca R, et al
MALT1 / MLT1 (N-term)
1664-1
The Protein Kinase C-Responsive Inhibitory Domain of CARD11 Functions in NF- B Activation To Regulate the Association of Multiple Signaling Cofactors That Differentially Depend on Bcl10 and MALT1 for AssociationMolecular and Cellular Biology 28 (2008) 5668-5686McCully RR and Pomerantz JLWB
MARCKS Phospho (pS158)
2156-1
PhosphoMARCKS drives motility of mouse melanoma cellsCell Signal 22 (2010) 1097-1103Chen X, Rotenberg SAWB
MARCKS Phospho (pS158)
2156-1
Thrombin and Collagen Induce a Feedback Inhibitory Signaling Pathway in Platelets Involving Dissociation of the Catalytic Subunit of Protein Kinase A from an NFkappaB-IkappaBJ Biol Chem 285 (2010) 18352-18363Gambaryan S, Kobsar A, Rukoyatkina N, et al
Mcl-1
1239-1
Bcl-2 family proteins are essential for platelet survivalCell Death and Differentiation 14 (2007) 943–951Zhang H, Nimmer PM, Tahir SK, et alWB
Mcl-1
1239-1
Gprc5a Deletion Enhances the Transformed Phenotype in Normal and Malignant Lung Epithelial Cells by Eliciting Persistent Stat3 Signaling Induced by Autocrine Leukemia Inhibitory FactorCancer Res 70 (2010) 8917-8926Chen Y, Deng J, Fujimoto J, et al
Mcl-1
1239-1
Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemiaBlood 113 (2009) 4403 - 4413Vogler M, Butterworth M, Majid A, et alIP
Mcl-1
1239-1
Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemiaBlood 115 (2010) 4497-4506Buchner M, Baer C, Prinz G, et alWB
Mcl-1
1239-1
Effective gene-viral therapy of leukemia by a new fiber chimeric oncolytic adenovirus expressing TRAIL: in vitro and in vivo evaluationMol. Cancer Ther. 8 (2009) 1387 - 1397Jin J, Liu H, Yang CM, et al
Mcl-1
1239-1
mir-29 regulates Mcl-1 protein expression and apoptosisOncogene 26 (2007) 6133–6140Mott JL, Kobayashi S, Bronk SF, et alICC
MEK1/MEK2 Phospho (pS218/222)
1470-1
Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumorMol Cancer Ther 8 (2009) 152-159Huynh H, Lee JW, Chow PK, et alWB
MEK1/MEK2 Phospho (pS218/222)
1470-1
Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinomaMol Cancer Ther 6 (2007) 138-146Huynh H, Soo KC, Chow PKH, et alWB
MEKK2
1662-1
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMol. Cell. Biol. 29 (2009) 6515 - 6526Chaveroux C, Jousse C, Cherasse Y, et al
MEKK3 (C-term)
1673-1
Expression profiles of protein tyrosine kinase genes in human embryonic stem cellsReproduction 136 (2008) 423–432Son M, Kim J, Han H, et alWB
MEKK3 (C-term)
1673-1
Phosphorylation of MEKK3 at Threonine 294 Promotes 14-3-3 Association to Inhibit Nuclear Factor B ActivationJ. Biol. Chem. 283 (2008) 13261 - 13268Matitau AE, Scheid MPIP
MEKK3 (C-term)
1673-1
PLX4032, a Selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAFWT melanoma cellsPigment Cell Melanoma Res 23 (2010) 190-200Halaban R, Zhang W, Bacchiocchi A, et alIP
MEKK3 (N-term)
1672-1
Phosphorylation of MEKK3 at Threonine 294 Promotes 14-3-3 Association to Inhibit Nuclear Factor B ActivationJ. Biol. Chem. 283 (2008) 13261 - 13268Matitau AE, Scheid MPIP
MEKK3 (N-term)
1672-1
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMol. Cell. Biol. 29 (2009) 6515 - 6526Chaveroux C, Jousse C, Cherasse Y, et al
Met
1996-1
Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatmentCancer Sci 101 (2010) 1270–1278Sakamoto K, Sakurai S, Kanda T, et alIHC
Met
1996-1
Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatmentCancer Sci 101 (2010) 1270-1278Sakamoto K, Sakurai S, Kanda T, et alIHC
Midkine (C-term)
1937-1
High-level soluble expression, purification and characterization of active human midkine from Escherichia coliProtein Expr Purif 70 (2010) 270-276Yan WK, Goette M, Hofmann G, et alWB
Midkine (C-term)
1937-1
Promotion of self-renewal of embryonic stem cells by midkineActa Pharmacol Sin 31 (2010) 629-637Yao X, Tan Z, Gu B, et alWB, ICC
MKK4
1650-1
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMol. Cell. Biol. 29 (2009) 6515 - 6526Chaveroux C, Jousse C, Cherasse Y, et al
MKK7 (C-term)
1949-1
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMol. Cell. Biol. 29 (2009) 6515 - 6526Chaveroux C, Jousse C, Cherasse Y, et al
MKP-3
2138-1
Myocardial ischemic postconditioning against ischemia-reperfusion is impaired in ob/ob miceAm J Physiol Heart Circ Physiol 295 (2008) H1580–H1586Bouhidel O, Pons S, Souktani R, et alWB
MLCK
2095-1
Protection of human corneal epithelial cells from hypoxia-induced disruption of barrier function by hepatocyte growth factorExp Eye Res 90 (2010) 337-343Kimura K, Teranishi S, Kawamoto K, et alWB
MLK-3 (C-term)
2000-1
Mixed Lineage Kinase-3/JNK1 Axis Promotes Migration of Human Gastric Cancer Cells following Gastrin StimulationMol Endocrinol 24 (2010) 598-607Mishra P, Senthivinayagam S, Rangasamy V, et al
MMP-12
1906-1
Mechanism of Diastolic Stiffening of the Failing Myocardium and Its Prevention by Angiotensin Receptor and Calcium Channel BlockersJ Cardiovasc Pharmacol. 54 (2009) 47-56Cheng XW, Okumura K, Kuzuya M, et alWB
MMP-12
1906-1
Photorejuvenation induced by 5-aminolevulinic acid photodynamic therapy in patients with actinic keratosis: A histologic analysisJ Am Acad Dermatol 62 (2010) 85-95Park MY, Sohn S, Lee ES, et alIHC
MMP-12
1906-1
Minocycline Prevents Osmotic Demyelination Syndrome by Inhibiting the Activation of MicrogliaJ Am Soc Nephrol 21 (2010) 2090-2098 Suzuki H, Sugimura Y, Iwama S, et al
MMP-14
2010-1
Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP–dependent proteolysis in 3-dimensional collagen matricesBlood 114 (2009) 237 - 247Stratman AN, Saunders WN, Sacharidou A, et al
MMP-14
2010-1
MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matricesJ Cell Sci 122 (2009) 4558-4569Fisher KE, Sacharidou A, Stratman AN, et al
MMP-14
2010-1
Prevention of Ischemia/Reperfusion-Induced Accumulation of Matrix Metalloproteinases in Rat Lung by Preconditioning with Nitric OxideJournal of Surgical Research 152 (2009) 198-208Waldow T, Witt W, Buzin A, et alWB
MMP-17
2011-1
The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomesMol Biol Cell 22 (2011) 202-215Cornfine S, Himmel M, Kopp P, et al
MMP-2
1948-1
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasionBreast Cancer Res. 11 (2009) R13Eiseler T, Döppler H, Yan IK, et al
MMP-2
2763-1
B-RafV600E and thrombospondin-1 promote thyroid cancer progressionProc Natl Acad Sci U S A 107 (2010) 10649-10654Nucera C, Porrello A, Antonello ZA, et alIHC
MMP-3
1908-1
Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti ratExp Biol Med (Maywood) 235 (2010) 1244-1256Al-Dasooqi N, Gibson RJ, Bowen JM, et al
MMP-3
1908-1
Photorejuvenation induced by 5-aminolevulinic acid photodynamic therapy in patients with actinic keratosis: A histologic analysisJ Am Acad Dermatol 62 (2010) 85-95Park MY, Sohn S, Lee ES, et alIHC
MMP-8
2145-1
The Molecular Mechanisms of Cervical Ripening Differ between Term and Preterm BirthEndocrinology 152 (2011) 1036-1046Holt R, Timmons BC, Akgul Y, et al
MMP-9
2551-1
B-RafV600E and thrombospondin-1 promote thyroid cancer progressionProc Natl Acad Sci U S A. 2010Nucera C, Porrello A, Antonello ZA, et alIHC
Mo25
2027-1
Identification of the Serine 307 of LKB1 as a Novel Phosphorylation Site Essential for Its Nucleocytoplasmic Transport and Endothelial Cell AngiogenesisMol Cell Biol. 29 (2009) 3582-3596Xie ZL, Dong YZ, Zhang JH, et alWB
Moesin
2036-1
Participation of ezrin in bacterial uptake by trophoblast giant cellsReprod Biol Endocrinol (2009) 7:95Watanabe K, Tachibana M, Kim S, et alWB
MSK1 Phospho (pS376)
1611-1
Pharmacological Modulation of Glutamate Transmission in a Rat Model of L-DOPA-Induced Dyskinesia: Effects on Motor Behavior and Striatal Nuclear SignalingJ. Pharmacol. Exp. Ther. 330 (2009) 227 - 235Rylander D, Recchia A, Mela F, et alIHC
Mst1
1942-1
Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cellsCell Calcium 46 (2009) 73-84Ulloa A, Gonzales AL, Zhong M, et alWB
Mst1
1942-1
Orai1, a critical component of store-operated Ca2+ entry, is functionally associated with Na+/Ca2+ exchanger in proliferating human arterial myocytesAm J Physiol Cell Physiol 297 (2009) C1103 - C1112Baryshnikov SG, Pulina MV, Zulian A, et al
Mst2 (N-term)
1943-1
MST kinases monitor actin cytoskeletal integrity and signal via JNK stress-activated kinase to regulate p21Waf1/Cip1 stabilityMol. Cell. Biol.29 (2009) 6380 - 6390Densham R, O'Neill E, Munro J, et al
Mst2 (N-term)
1943-1
Heat Shock Protein 90 Inhibition Depletes LATS1 and LATS2, Two Regulators of the Mammalian Hippo Tumor Suppressor PathwayCancer Res 70 (2010) 8642-8650Huntoon CJ, Nye MD, Geng L, et al
Mst2 (N-term)
1943-1
Proapoptotic Kinase MST2 Coordinates Signaling Crosstalk between RASSF1A, Raf-1, and AktCancer Res 70 (2010) 1195-1203Romano D, Matallanas D, Weitsman G, et al
Mst2 (N-term)
1943-1
Heterogeneous Nuclear Ribonucleoprotein H Blocks MST2-Mediated Apoptosis in Cancer Cells by Regulating a-raf TranscriptionCancer Res 70 (2010) 1679-1688Rauch J, O'Neill E, Mack B, et al
Mst2 (N-term)
1943-1
Mammalian Ste20-like Kinase (Mst2) Indirectly Supports Raf-1/ERK Pathway Activity via Maintenance of Protein Phosphatase-2A Catalytic Subunit Levels and Consequent Suppression of Inhibitory Raf-1 PhosphorylationJ Biol Chem 285 (2010) 15076-15087Kilili GK, Kyriakis JM
Mst4
2049-1
Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization ComplexDevelopmental Cell 16 (2009) 551-562Klooster JP, Jansen M, Yuan J, et alWB, ICC
Mst4 (pT178)/Mst3 (pT190)/STK25 (pT174) Phospho
2160-1
Human NDR Kinases Control G1/S Cell Cycle Transition by Directly Regulating p21 StabilityMol Cell Biol 31 (2011) 1382-1395Cornils H, Kohler RS, Hergovich A, et al
mTOR/FRAP
1612-1
The role of mTOR and phospho-p70S6K in pathogenesis and progression of gastric carcinomas: an immunohistochemical study on tissue microarrayJ Exp Clin Cancer Res 28 (2009) : 152Xiao L, Wang YC, Li WS, et alIHC
mu-opioid receptor
3675-1
Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies.Br J Pharmacol.Doll C, Konietzko J, et alWB
mu-opioid receptor
3675-1
UMB-3, a novel rabbit monoclonal antibody, for assessing μ-opioid receptor expression in mouse, rat and human formalin-fixed and paraffin-embedded tissues.Regul Pept.Lupp A, Richter N, et alWB, IHC, IP
MUC1 isoform 7
1797-1
MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1Cancer Res 70 (2010) 378-387Sachdeva M, Mo YY.
MYPT1/MYPT2 (C-term)
1488-1
Myosin Phosphatase-Targeting Subunit 1 Regulates Mitosis by Antagonizing Polo-like Kinase 1Developmental Cell 14 (2008) 787–797Yamashiro S, Yamakita Y, Totsukawa G, et al
MYPT1/MYPT2 (C-term)
1488-1
Enhanced Skeletal Muscle Contraction with Myosin Light Chain Phosphorylation by a Calmodulin-sensing KinaseThe Journal of Biological Chemistry 282 (2007) 20447–20454Ryder JW, Lau KS, Kamm KE, et alWB
MYPT1/MYPT2 (C-term)
1488-1
Prostanoid F receptors elicit an inotropic effect in rat left ventricle by enhancing myosin light chain phosphorylationCardiovascular Research 80 (2008) 407-415Riise J, Nguyen CHT, Qvigstad E, et alWB
Na+/K+ ATPase α
2047-1
A Mouse Model for Degeneration of the Spiral LigamentJ Assoc Res Otolaryngol 10 (2009) 161-172Kada S, Nakagawa T, Ito JIHC
Na+/K+ ATPase α
2047-1
Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesisDev Biol 336 (2009) 169-182Daley WP, Gulfo KM, Sequeira SJ, et alICC
NAK/TBK1 (N-term)
1670-1
TBK1 does not play a role in the control of in vitro Burkholderia pseudomallei growthTransactions of the Royal Society of Tropical Medicine and Hygiene 102/S1 (2008) S95 - S100Panomketa P, Splitterc G, Harmsc J, et alWB
NF-κB (p105/p50)
1559-1
Transcriptional regulation of parathyroid hormone-related protein promoter P2 by NF-κB in adult T-cell leukemia/lymphomaLeukemia 21 (2007) 1752–1762Nadella MVP ,Dirksen WP, Nadella KS, et alWB
NF-kappa-B p65
2229-1
The N-terminus of Adenovirus 12 E1A Inhibits MHC Class I Expression by Preventing Phosphorylation of NF-kappa B p65 Ser276 Through Direct BindingJ Virol 84 (2010) 7668-7674Jiao J, Guan H, Lippa AM, et al
Nibrin/NBS1
1507-1
ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA DamageSci Signal 3 (2010) rs3Bensimon A, Schmidt A, Ziv Y, et al
Nibrin/NBS1
1507-1
Ionizing Radiation Induces Ataxia Telangiectasia Mutated-Dependent Checkpoint Signaling and G2 But Not G1 Cell Cycle Arrest in Pluripotent Human Embryonic Stem CellsStem Cells 27 (2009) 1822 -1835Momcilovic O, Choi S, Varum S, et al
Nibrin/NBS1
1507-1
Role of SIRT1 in homologous recombinationDNA Repair (Amst) 9 (2010) 383-393Uhl M, Csernok A, Aydin S, et alWB
NOTCH1
1935-1
CDK8 is a colorectal cancer oncogene that regulates β-catenin activityNature 455 (2008) 547- 553Firestein R, Bass AJ, Kim SY, et alWB
NOTCH1
1935-1
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascadeJ Clin Invest 120 (2010) 103-114Ma J, Meng Y, Kwiatkowski DJ, et alWB
NOTCH1
1935-1
Evaluation of Selective -Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial DesignMol Cancer Ther 9 (2010) 1618-1628Wei P, Walls M, Qiu M, et alIHC
NOTCH1
1935-1
Notch1 Functions as a Tumor Suppressor in a Model of K-ras–Induced Pancreatic Ductal AdenocarcinomaCancer Res 70 (2010) 4280-4286Hanlon L, Avila JL, Demarest RM, et al
NOX4
3174-1
Nox4 is a novel inducible source of reactive oxygen species in monocytes and macrophages and mediates oxidized low density lipoprotein-induced macrophage death.Circ.Res. 106(9): 1489-97 (2010)Lee, C.F., Qiao, M. Schroeder, K., Zhao, Q. and Asmis, R.IP, ICC
NOX4
3187-1
Nox4 is a novel inducible source of reactive oxygen species in monocytes and macrophages and mediates oxidized low density lipoprotein-induced macrophage death.Circ.Res. 106(9): 1489-97 (2010)Lee, C.F., Qiao, M. Schroeder, K., Zhao, Q. and Asmis, R.IP, ICC
Nrf2
2178-1
Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated TranscriptionPLoS One. 4 (2009) e5757Yang LC, Calingasan NY, Thomas B, et alWB
Nrf2
2178-1
MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphomaBlood 116 (2010) 1515-1523Milhollen MA, Traore T, Adams-Duffy J, et al
Nrf2
2178-1
Antioxidant defence systems and generation of reactive oxygen species in osteosarcoma cells with defective mitochondria: Effect of seleniumBiochim Biophys Acta 1797 (2010) 890-896Wojewoda M, Duszyński J, Szczepanowska JWB
Nrf2 Phospho (pS40)
2073-1
Up-Regulation of Human CYP2J2 in HepG2 Cells by Butylated Hydroxyanisole Is Mediated by c-Jun and Nrf2Mol Pharmacol 77 (2010) 987-994Lee AC, Murray M
Nrf2 Phospho (pS40)
2073-1
Antioxidant defence systems and generation of reactive oxygen species in osteosarcoma cells with defective mitochondria: Effect of seleniumBiochim Biophys Acta 1797 (2010) 890-896Wojewoda M, Duszyński J, Szczepanowska JWB
p-nitrobenzyl mesylate (PNBM)
3700-1
Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replicationGenes Dev 24 (2010) 2627-2639huluunbaatar U, Roller R, Feldman ME, et al
p120 Catenin
1506-1
p120 catenin is associated with desmogleins when desmosomes are assembled in high-Ca2+ medium but not when disassembled in low-Ca2+ medium in DJM-1 cellsJournal of Dermatology 35 (2008) 317–324Kanno M, Aoyama Y, Isa Y, et alIP, ICC
p120 Catenin
2806-1
Conformational epitopes at cadherin calcium-binding sites and p120-catenin phosphorylation regulate cell adhesionMol Biol CellYuliya I. Petrova, MarthaJoy M. Spano, and Barry M. GumbinerIF
p27/Kip1 Phospho (pS10)
2187-1
Phosphorylation of p27Kip1 by Epstein-Barr Virus Protein Kinase Induces Its Degradation through SCFSkp2 Ubiquitin Ligase Actions during Viral Lytic ReplicationJ. Biol. Chem. 284 (2009) 18923 - 18931Iwahori S, Murata T, Kudoh A, et alWB
p38 MAPK
1544-1
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expressionBMC Cell Biol 11 (2010) :10Ziegler N, Alonso A, Steinberg T, et alWB
p38 MAPK Phospho (pT180/pY182)
1229-1
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expressionBMC Cell Biol 11 (2010) :10Ziegler N, Alonso A, Steinberg T, et alWB
p38 MAPK Phospho (pT180/pY182)
1229-1
Preconditioning by inhaled nitric oxide prevents hyperoxic and ischemia/reperfusion injury in rat lungsPulmonary Pharmacology & Therapeutics 21 (2008) 418–429Waldow T, Witt W, UlmerA, et alWB
p40 / phox
2124-1
Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensisJ Leukoc Biol 88 (2010) 791-805McCaffrey RL, Schwartz JT, Lindemann SR, et al
p53
1026-1
Immunohistochemistry in diagnostic surgical pathology: contributions of protein life-cycle, use of evidence-based methods and data normalization on interpretation of immunohistochemical stainsInt J Clin Exp Pathol 3 (2009) 169-176Idikio HAIHC
p53 (N-term)
1005-1
PRIMA-1Met/APR-246 Induces Apoptosis and Tumor Growth Delay in Small Cell Lung Cancer Expressing Mutant p53Clin Cancer Res 17 (2011) 2830-2841Zandi R, Selivanova G, Christensen CL, et al
p53 Phospho (pS46)
2190-1
Immunohistochemistry in diagnostic surgical pathology: contributions of protein life-cycle, use of evidence-based methods and data normalization on interpretation of immunohistochemical stainsInt J Clin Exp Pathol 3 (2009) 169-176Idikio HAIHC
p70 S6 Kinase
1175-1
mTOR Signaling Pathway Is a Target for the Treatment of Colorectal CancerAnn Surg Oncol 16 (2009) 2617-2628Zhang YJ, Dai Q, Sun DF, et alIHC
p70 S6 Kinase
1175-1
The role of mTOR and phospho-p70S6K in pathogenesis and progression of gastric carcinomas: an immunohistochemical study on tissue microarrayJ Exp Clin Cancer Res 28 (2009) : 152Xiao L, Wang YC, Li WS, et alIHC
p70 S6 Kinase
1175-1
Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenograftsMol Cancer Ther 5 (2006) 2494–2502Birle DC and Hedley DWWB
p70 S6 Kinase
1175-1
Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancerInt J Colorectal Dis 24 (2009) 629-639Zhang YJ, Zhao SL, Tian XQ, et alIHC
p70 S6 Kinase (N-term)
1494-1
Sirolimus-induced signaling modifications in Kaposi s sarcoma with resolution in a liver transplant recipientClin Transplant 24 (2010) 127–132Ho CM, Huang SF, Hu RH, et alIHC
p70 S6 Kinase (N-term)
1494-1
An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast CancerCancer Res 68 (2008) 6084-6091Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, et alRPPA
p70 S6 Kinase (N-term)
1494-1
Targeted Inhibition of Inducible Nitric Oxide Synthase Inhibits Growth of Human Melanoma In vivo and Synergizes with ChemotherapyClin Cancer Res 16 (2010) 1834-1844Sikora AG, Gelbard A, Davies MA, et al
p70 S6 Kinase (N-term)
1494-1
Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell CharacteristicsCancer Res.69 (2009) 4116 - 4124Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, et al
p70 S6 Kinase (N-term)
1494-1
RalA functions as an indispensable signal mediator for nutrient sensing systemJ. Biol. Chem. 283 (2008) 35053 - 35059Maehama T, Tanaka M, Nishina H, et alWB
p70 S6 Kinase Phospho (pT421/pS424)
1135-1
Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeuticsMol Cancer Ther 6 (2007) 2828-2842Choong LY, Lim S, Loh MCS, et alIHC?
p73
1636-1
Directed expression of dominant-negative p73 enables proliferation of cardiomyocytes in miceJournal of Molecular and Cellular Cardiology 45 (2008) 411-419Ebelt H, Zhang Y, Köhler K, et alIP
p73
1636-1
P53 family members regulate the expression of the apolipoprotein D geneJ. Biol. Chem. 284 (2009) 872 - 883Sasaki Y, Negishi H, Koyama R, et alWB
Pan-Cadherin
2019-1
Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1rPNAS 106 (2009) 1802 - 1807Pape EL, Passeron T, Giubellino A, et alWB
Parkin
1679-1
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant miceProc Natl Acad Sci U S A 107 (2010) 15145-15150Poulogiannis G, McIntyre RE, Dimitriadi M, et al
PARP-1 (Cleaved p25)
1051-1
Low-dose hypersensitive cH2AX response and infrequent apoptosis in epidermis from radiotherapy patientsRadiotherapy and Oncology 88 (2008) 388-397Simonssona M, Qvarnstro¨ma F, Nymanb J,et alIHC
PARP-1 (Cleaved p25)
1051-1
Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10Cell Mol Life Sci 66 (2009) 3053-3065Dittmer A, Hohlfeld K, Lützkendorf J, et alWB
PARP-1 (Cleaved p25)
1051-1
Overexpression of Galectin-7, A Myoepithelial Cell Marker, Enhances Spontaneous Metastasis of Breast Cancer CellsAm J Pathol 176 (2010) 3023-3031Demers M, Rose AA, Grosset AA, et al
PARP-1 (Cleaved p25)
1051-1
An Ang1-Tie2-PI3K axis in Neural Progenitor Cells Initiates Survival Responses Against Oxygen And Glucose DeprivationNeuroscience 160 (2009) 371-381Bai Y, Meng Z, Cui M, et alWB
PARP-1 (Cleaved p85)
1074-1
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cellsFree Radic Biol Med 48 (2010) 713-726Yoon MJ, Kim EH, Lim JH, et alWB
PARP-1 (Cleaved p85)
1074-1
Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancerMol. Cancer Ther. 7 (2008) 1533 - 1542Shangary S, Ding K, Qiu S, et alWB
PARP-1 (Cleaved p85)
1074-1
hTERT-promoter driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletionsHum Gene Ther 19 (2008) 1383-1400Doloff JC, Waxman DJ, Jounaidi YWB
PAX2
2549-1
Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitisCarcinogenesis 31 (2010) 1734-1741Cui X, Jin Y, Poudyal D, et al
Paxillin (N-term)
1500-1
Human mesenchymal stem cells in contact with their environment: surface characteristics and the integrin systemJ. Cell. Mol. Med. 11 (2007) 21-38Docheva D, Popov C, Mutschler W, et al
Paxillin (N-term)
1500-1
Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transitionFASEB J. 2010Mendez MG, Kojima SI, Goldman RDICC
Paxillin (N-term)
1500-1
Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopyJ. Cell. Mol. Med. 12 (2008) 537-552Docheva D, Padula D, Popov C, et alICC
Paxillin (N-term)
1500-1
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillinCellular Signalling 19 (2007) 1733–1744Schmalzigaug R, Garron ML, Roseman JY, et alIP, ICC
Paxillin (N-term)
1500-1
Recruitment of vimentin to the cell surface by β3 integrin and plectin mediates adhesion strengthJ Cell Sci 122 (2009) 1390-1400Bhattacharya R, Gonzalez AM, Debiase PJ, et alICC
Paxillin (N-term)
1500-1
Recruitment of vimentin to the cell surface by β3 integrin and plectin mediates adhesion strengthJ. Cell Sci.122 (2009) 1390 - 1400Bhattacharya R, Gonzalez AM, DeBiase PJ, et al
Paxillin (N-term)
1500-1
Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistinAm J Physiol Cell Physiol 297 (2009) C1466-C1476Jiang C, Zhang H, Zhang W, et al
PDGF Receptor beta
1469-1
Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neuronsMolecular Brain 2008 1:20Beazely MA, Weerapura M , MacDonald JFIP
PDGF Receptor beta
1469-1
Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nervesJ Peripher Nerv Syst 14 (2009) 165-176Yamazaki T, Sabit H, Oya T, et alIHC
PDGF Receptor beta
1469-1
Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatmentCancer Sci 101 (2010) 1270–1278Sakamoto K, Sakurai S, Kanda T, et alIHC
PDGF Receptor beta
1469-1
Platelet-derived Growth Factor Selectively Inhibits NR2B-containing N-Methyl-D-aspartate Receptors in CA1 Hippocampal NeuronsJ. Biol. Chem. 284 (2009) 8054 - 8063Beazely MA, Lim A, Li HB, et alIP, ICC
PDGF Receptor beta
1469-1
Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatmentCancer Sci 101 (2010) 1270-1278Sakamoto K, Sakurai S, Kanda T, et alIHC
PDK1
1901-1
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression.J Biol ChemBlock K, Eid A, Griendling KK, Lee DY, Wittrant Y, Gorin Y.WB
PDk1
1624-1
PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac DevelopmentMol Cell Biol 30 (2010) 3711-3721Feng Q, Di R, Tao F, et al
PGP9.5
2932-1
Optical clearing improves the imaging depth and signal-to-noise ratio for digital analysis and three-dimensional projection of the human enteric nervous systemNeurogastroenterol Motil Y.-A. Liu, Y. Chen, et alIHC
PI3-kinase p110 subunit alpha
1683-1
Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K ActivationCancer Cell 16 (2009) 463-474Jaiswal BS, Janakiraman V, Kljavin NM, et alWB
PI3-kinase p110 subunit alpha
1683-1
Different Changes in Protein and Phosphoprotein Levels Result from Serum Starvation of High-Grade Glioma and Adenocarcinoma Cell LinesJ Proteome Res 9 (2010) 179-191Levin VA, Panchabhai SC, Shen L, et alWB
PI3-kinase p110 subunit alpha
1683-1
Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941Cancer Cell 15 (2009) 429-440Junttila TT, Akita RW, Parsons K, et alWB
PI3-kinase p110 subunit beta (N-term)
1593-1
Rhinovirus Activates Interleukin-8 Expression via a Src/p110 β Phosphatidylinositol 3-Kinase/Akt Pathway in Human Airway Epithelial CellsJournal of Virology 81 (2007) 1186–1194Bentley JK, Newcomb DC, Goldsmith AM, et alWB
PI3-kinase p110 subunit delta
1575-1
Differential Enhancement of Breast Cancer Cell Motility and Metastasis by Helical and Kinase Domain Mutations of Class IA Phosphoinositide 3-KinaseCancer Res 69 (2009) 8868-8876Pang H, Flinn R, Patsialou A, et alWB
PI3-kinase p110 subunit delta
1575-1
Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K ActivationCancer Cell 16 (2009) 463-474Jaiswal BS, Janakiraman V, Kljavin NM, et alWB
PI3-kinase p110 subunit delta
1575-1
Differential Enhancement of Breast Cancer Cell Motility and Metastasis by Helical and Kinase Domain Mutations of Class IA Phosphoinositide 3-KinaseCancer Res 69 (2009) 8868-8876Pang H, Flinn R, Patsialou A, et al
PIAS1/2/3
2474-1
Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification MachineryPLoS Pathog 5 (2009) e1000493Chang TH, Kubota T, Matsuoka M, et al
PKA, RII Phospho (pS99)
1151-1
Phosphorylation of the PKA regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation and calcium signaling in cardiac cellsJ Biol Chem. 283 (2008) 24145-24154Manni S, Mauban JH, Ward CW, et alWB
PKA, RII Phospho (pS99)
1151-1
Phosphorylation of the cAMP-dependent Protein Kinase (PKA) Regulatory Subunit Modulates PKA-AKAP Interaction, Substrate Phosphorylation, and Calcium Signaling in Cardiac CellsJ. Biol. Chem. 283 (2008) 24145 - 24154Manni S, Mauban JH, Ward CW, et alWB
PKC alpha
1510-1
PKCα tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1Exp Cell Res 315 (2009) 1415-1428Pysz MA, Leontieva OV, Bateman NW, et alWB, IHC
PKC alpha Phospho (pT497)
2378-1
Protein kinase C mRNA and protein expressions in hypobaric hypoxia-induced cardiac hypertrophy in ratsActa Physiol (Oxf) 198 (2010) 431–440Uenoyama M, Ogata S, Nakanishi K, et alIHC
PKC delta
2053-1
PKCδ influences p190 phosphorylation and activity: Events independent of PKCδ- mediated regulation of endothelial cell stress fiber and focal adhesion formation and barrier functionBiochim Biophys Acta 1790 (2009) 1179-1190Fordjour AK, Harrington EOWB
PKC gamma Phospho (pT514)
2400-1
Dominant Inhibition of Akt/PKB signaling by the Matrix protein of a negative-strand RNA virusJ Virol 85 (2011) 422-431Dunn EF, Connor JH
PKC gamma Phospho (pT514)
2400-1
Dominant Inhibition of Akt/Protein Kinase B Signaling by the Matrix Protein of a Negative-Strand RNA VirusJ Virol 85 (2011) 422-431Dunn EF, Connor JH
PKC mu / PKD
1986-1
Protein Kinase D1 Mediates Stimulation of DNA Synthesis and Proliferation in Intestinal Epithelial IEC-18 Cells and in Mouse Intestinal CryptsJ Biol Chem 286 (2011) 511-520Sinnett-Smith J, Rozengurt N, Kui R, et al
PKC mu / PKD Phospho (pS916)
2085-1
A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivoMol Cancer Ther 9 (2010) 1136-1146Harikumar KB, Kunnumakkara AB, Ochi N, et al
PKR (C-term)
1511-1
eIF2α Phosphorylation-Dependent Translation in CA1 Pyramidal Cells Impairs Hippocampal Memory Consolidation without Affecting General TranslationJ Neurosci 30 (2010) 2582-2594Jiang Z, Belforte JE, Lu Y, et alWB
PKR (N-term)
1508-1
Viral Double-stranded RNAs from Vaccinia Virus Early or Intermediate Gene Transcripts Possess PKR Activating Function, Resulting in NF-κB Activation, When the K1 Protein Is Absent or MutatedJ Biol Chem 286 (2011) 7765-7778Willis KL, Langland JO, Shisler JL
PKR (N-term)
1508-1
The effect of the vaccinia K1 protein on the PKR-eIF2α pathway in RK13 and HeLa cellsVirology 394 (2009) 73-81Willis KL, Patel S, Xiang Y, et alWB
PKR Phospho (pT446)
1120-1
Mechanisms of Protein Kinase PKR-mediated Amplification of Interferon Beta Induction by C Protein-deficient Measles VirusJ Virol 84 (2010) 380-386McAllister CS, Toth AM, Zhang P, et al
PKR Phospho (pT446)
1120-1
Severe Acute Respiratory Syndrome Coronavirus Triggers Apoptosis via Protein Kinase R but Is Resistant to Its Antiviral ActivityJ Virol 83 (2009) 2298-2309Krähling V, Stein DA, Spiegel M, et alWB
PKR Phospho (pT446)
1120-1
Hepatitis C Virus Blocks Interferon Effector Function by Inducing Protein Kinase R PhosphorylationCell Host Microbe 6 (2009) 513-522Garaigorta U, Chisari FVWB
PKR Phospho (pT446)
1120-1
RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKRJ. Biol. Chem. 284 (2009) 29350 - 29356Toth AM, Li Z, Cattaneo R, et alWB
PKR Phospho (pT446)
1120-1
The effect of the vaccinia K1 protein on the PKR-eIF2α pathway in RK13 and HeLa cellsVirology 394 (2009) 73-81Willis KL, Patel S, Xiang Y, et alWB
PKR Phospho (pT446)
1120-1
Chikungunya Virus Induces IPS-1-Dependent Innate Immune Activation and Protein Kinase R-Independent Translational ShutoffJ Virol 85 (2011) 606-620White LK, Sali T, Alvarado D, et al
PKR Phospho (pT446)
1120-1
Viral Double-stranded RNAs from Vaccinia Virus Early or Intermediate Gene Transcripts Possess PKR Activating Function, Resulting in NF-κB Activation, When the K1 Protein Is Absent or MutatedJ Biol Chem 286 (2011) 7765-7778Willis KL, Langland JO, Shisler JL
PKR Phospho (pT446)
1120-1
Sendai Virus C Protein Plays a Role in Restricting PKR Activation by Limiting the Generation of Intracellular Double-Stranded RNAJ Virol 82 (2008) 10102-10110Takeuchi K, Komatsu T, Kitagawa Y, et alWB
PKR Phospho (pT446)
1120-1
RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatmentVirology 396 (2010) 316-322Li Z, Wolff KC, Samuel CEWB
PKR Phospho (pT451)
2283-1
The C proteins of human parainfluenza virus type 1 limit double stranded RNA accumulation that would otherwise trigger MDA5 and PKR activationJ Virol 85 (2011) 1495-1506Boonyaratanakornkit J, Bartlett E, Schomacker H, et al
PKR Phospho (pT451)
2283-1
The C Proteins of Human Parainfluenza Virus Type 1 Limit Double-Stranded RNA Accumulation That Would Otherwise Trigger Activation of MDA5 and Protein Kinase RJ Virol 85 (2011) 1495-1506Boonyaratanakornkit J, Bartlett E, Schomacker H, et al
PLAA
1566-1
Alteration in the activation state of new inflammation-associated targets by phospholipase A2-activating protein (PLAA)Cellular Signalling 20 (2008) 844-861Zhang F, Sha J, Wood TH, et alWB
PLAA
1566-1
UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1a TurnoverCell 134 (2008) 804–816Alexandru G, Graumann J, Smith GT, et alIP
PLAP
4206-1
Visual restoration and transplant connectivity in degenerate rats implanted with retinal progenitor sheetsEur J Neurosci 31 (2010) 508-520Seiler MJ, Aramant RB, Thomas BB, et alIHC
Plectin
1399-1
A Dystroglycan/Plectin Scaffold Mediates Mechanical Pathway Bifurcation in Lung Epithelial CellsJ Biol Chem 286 (2011) 6301-6310Takawira D, Budinger GR, Hopkinson SB, et al
Plectin
1399-1
TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeletonJ Cell Sci 121 (2008) 3476-3486Nery FC, Zeng J, Niland BP, et alWB
Plectin
1399-1
Recruitment of vimentin to the cell surface by β3 integrin and plectin mediates adhesion strengthJ Cell Sci 122 (2009) 1390-1400Bhattacharya R, Gonzalez AM, Debiase PJ, et alWB, ICC
Polyethylene Glycol (PEG) ELISA Kit
6100-1
Minimal Effects of VEGF and Anti-VEGF Drugs on the Permeability or Selectivity of RPE Tight JunctionsInvest Ophthalmol Vis Sci 51 (2010) 3216-3225Peng S, Adelman RA, Rizzolo LJ
PP1 alpha Phospho (pT320)
2167-1
Basis for MAP4 Dephosphorylation-related Microtubule Network Densification in Pressure Overload Cardiac HypertrophyJ Biol Chem 285 (2010) 38125-38140Cheng G, Takahashi M, Shunmugavel A, et al
PP1 alpha/beta
1950-1
Protein Phosphatase 1 (PP-1)-Dependent Inhibition of Insulin Secretion by Leptin in INS-1 Pancreatic β-Cells and Human Pancreatic IsletsEndocrinology 152 (2011) 1800-1808Kuehnen P, Laubner K, Raile K, et al
PP2A
1512-1
Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cellsCancer Letters 259 (2008) 28–38Singh AP, Bafna S, Chaudhary K, et alWB, IHC
PP2A Phospho (pY307)
1155-1
Domains Necessary for G 12 Binding and Stimulation of Protein Phosphatase-2A (PP2A): Is G 12 a Novel Regulatory Subunit of PP2A?Mol Pharmacol 71 (2007) 1268–1276Zhu D, Tate RI, Ruediger R, et alWB
PP2A Phospho (pY307)
1155-1
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2ABiogerontology 10 (2009) 443-456Shay KP, Hagen TMWB
PP2A Phospho (pY307)
1155-1
C3G mediated suppression of malignant transformation involves activation of PP2A phosphatases at the subcortical actin cytoskeletonExperimental cell reserarch 313 (2007) 3881-3891Martín-Encabo S, Santos E, Guerrero CWB, IP
PP2A Phospho (pY307)
1155-1
SCF induces γ-globin gene expression by regulating downstream transcription factor COUP-TFIIBlood 114 (2009) 187 - 194Aerbajinai W, Zhu J, Kumkhaek C, et al
PP2A Phospho (pY307)
1155-1
SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemiaBlood 115 ( 2010) 615-625Cristóbal I, Blanco FJ, Garcia-Orti L, et al
PP2A Phospho (pY307)
1155-1
Cadmium activates MAPK pathway via induction of reactive oxygen species and inhibition of protein phosphatase 2A and 5Free Radical Biology and Medicine 45 (2008) 1035-1044Chen L, Liu L, Huang SL, et al
PP2A Phospho (pY307)
1155-1
Basis for MAP4 Dephosphorylation-related Microtubule Network Densification in Pressure Overload Cardiac HypertrophyJ Biol Chem 285 (2010) 38125-38140Cheng G, Takahashi M, Shunmugavel A, et al
PP2A Phospho (pY307)
1155-1
Transcriptional Regulation of Bim by FoxO3A Mediates Hepatocyte LipoapoptosisThe Journal of Biological Chemistry 282 (2007) 27141–27154Barreyro FJ, Kobayashi S, Bronk SF, et alWB
PP2A Phospho (pY307)
1155-1
Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J miceJ Lipid Res 51 (2010) 2642-2654Tripathy S, Torres-Gonzalez M, Jump DB
PP2A Phospho (pY307)
1155-1
Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A, 5, leading to activation of MAPK pathwayThe International Journal of Biochemistry & Cell Biology 41 (2009) 1284-1295Chen L, Liu L, Yin J, et alWB
PP2A Phospho (pY307)
1155-1
Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndromeProceedings of the National Academy of Sciences 105 (2008) 4429–4434Kim SH, Markham JA, Weiler IJ, et alWB
PP2A Phospho (pY307)
1155-1
PtdIns5P protects Akt from dephosphorylation through PP2A inhibitionBiochem Biophys Res Commun. 387 (2009) 127-131Ramel D, Lagarrigue F, Dupuis-Coronas S, et alWB
PP2A Phospho (pY307)
1155-1
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABLregulated SET proteinCancer Cell 8 (2005) 355-368Nevlani P, Santhanam S, Trotta R, et alIP
Progesterone Receptor
1483-1
Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell CharacteristicsCancer Res.69 (2009) 4116 - 4124Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, et al
Progesterone Receptor Phospho (pS190)
2258-1
Multiplexed Assessment of the Southwest Oncology Group-Directed Intergroup Breast Cancer Trial S9313 by AQUA Shows that Both High and Low Levels of HER2 Are Associated with Poor OutcomeAm J Pathol 176 (2010) 1639-1647Harigopal M, Barlow WE, Tedeschi G, et alIHC
Prostate-Specific Antigen (PSA)
1984-1
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cellsAnticancer Drugs 21 (2010) 423-432Morrissey C, Gallis B, Solazzi JW, et alWB
Protein Kinase D2
1969-1
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumoursGut 59 (2010) 1316-1330Azoitei N, Pusapati GV, Kleger A, et al
PTEN (C-term)
1539-1
Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxideLife Sci 86 (2010) 192-198Liu L, Jiang Y, Zhang H, et alWB
PTEN (C-term)
1539-1
miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxideToxicol In Vitro 24 (2010) 1168-1175Liu L, Jiang Y, Zhang H, et alWB
PTEN (C-term)
1539-1
miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxideToxicol In Vitro 24 (2010) 1168-1175Liu L, Jiang Y, Zhang H, et alWB
PTEN Phospho (pT366/pS370)
2195-1
Regulation of PTEN Stability and Activity by Plk3J Biol Chem 285 (2010) 39935-39942Xu D, Yao Y, Jiang X, et al
PUMA (C-term)
1652-1
PUMA Promotes Bax Translocation by Both Directly Interacting with Bax and by Competitive Binding to Bcl-XL during UV-induced ApoptosisMol Biol Cell 20 (2009) 3077-3087Zhang Y, Xing D, Liu LWB
PUMA (C-term)
1652-1
Tumor Necrosis Factor α Induces p53 Up-regulated Modulator of Apoptosis Expression in Colorectal Cancer Cell LinesDis Colon Rectum 53 (2010) 257-263Pastor DM, Irby RB, Poritz LSICC
PUMA (C-term)
1652-1
PUMA Promotes Bax Translocation by Both Directly Interacting with Bax and by Competitive Binding to Bcl-XL during UV-induced ApoptosisMol. Biol. Cell 20 (2009) 3077 - 3087Zhang YJ, Xing D, Liu LWB
PUMA (C-term)
1652-1
New caspase-independent but ROS-dependent apoptosis pathways are targeted in melanoma cells by an iron-containing cytosine analogueBiochem Pharmacol 79 (2010) 575-586Franke JC, Plötz M, Prokop A, et alWB
Radixin
2042-1
Participation of ezrin in bacterial uptake by trophoblast giant cellsReprod Biol Endocrinol (2009) 7:95Watanabe K, Tachibana M, Kim S, et alWB
Raf-1
1560-1
Progesterone Receptor Activation of Extranuclear Signaling Pathways in Regulating p53 Expression in Vascular Endothelial CellsMol Endocrinol 25 (2011) 421-432Hsu SP, Lee WS
Raf-1
1560-1
Ras effector pathways modulate scatter factor-stimulated NF-κB signaling and protection against DNA damageOncogene 26 (2007) 4774–4796Fan S, Meng Q, Laterra JJ, et alWB
Raf-1
1560-1
Acute Insulin Signaling in Pancreatic Beta-Cells Is Mediated by Multiple Raf-1 Dependent PathwaysEndocrinology 151 (2010) 502-512Alejandro EU, Kalynyak TB, Taghizadeh F, et al
Raf-1
1560-1
PTPIP51, a novel 14-3-3 binding protein, regulates cell morphology and motility via Raf-ERK pathwayCellular Signalling 20 (2008) 2208-2220Yu CF, Han WL, Shi TP, et alIP
RanBP9
1928-1
The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodiesOncogene 27 (2008) 1281–1289Gast D, Riedle S, Issa Y, et alWB
Rap1GAP
1530-1
Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphologyPNAS 106 (2009) 3531 - 3536McAvoy T, Zhou MM, Greengard P, et alIHC
Rb
2655-1
Clinicopathologic Features of CDK6 Translocationassociated B-cell Lymphoproliferative DisordersAm J Surg Pathol. 33 (2009) 720-729Chen D, Law ME, Theis JD, et alIHC
RBBP4
2566-1
Metastasis Tumor Antigen 2 (MTA2) Is Involved in Proper Imprinted Expression of H19 and Peg3 During Mouse Preimplantation DevelopmentBiol Reprod 83 (2010) 1027-1035Ma P, Lin S, Bartolomei MS, et alWB
RelB
1661-1
Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal typeBlood 115 (2010) 1226-1237Huang Y, de Reyniès A, de Leval L, et al
ROCK1
1761-1
Pregnane X receptor activation protects rat hepatocytes against deoxycholic acid-induced apoptosisLiver Int 30 (2010) 284-297Zucchini-Pascal N, de Sousa G, Pizzol J, et alWB
RSK1
2004-1
Stimulated nuclear translocation of NF-κB and shuttling differentially depend on dynein and the dynactin complexPNAS 106 (2009) 2647 - 2652Shrum CK, DeFrancisco D, Meffert MKWB
RSK1 Phospho (pS380)
1468-1
The PKARIα Subunit of Protein Kinase A Modulates the Activation of p90RSK1 and Its FunctionJ. Biol. Chem. 284 (2009) 23670 - 23681Chaturvedi D, Cohen MS, Taunton J, et alWB
RSK1 Phospho (pS380)
1468-1
Regulation of Protein Kinase A Activity by p90 Ribosomal S6 Kinase 1J Biol Chem 284 (2009) 33070-33078Gao X, Patel TBWB
RSK1 Phospho (pS380)
1468-1
p90 Ribosomal S6 Kinase 1 (RSK1) and the Catalytic Subunit of Protein Kinase A (PKA) Compete for Binding the Pseudosubstrate Region of PKAR1 α: role in the regulation of PKA and RSK1 activitiesJ Biol Chem 285 (2010) 6970-6979Gao X, Chaturvedi D, Patel TB
RSK1 Phospho (pS380)
1468-1
Rapamycin induces transactivation of the EGFR and increases cell survivalOncogene 28 (2009) 1187–1196Chaturvedi D, Gao X, Cohen MS, et alWB
RSK1 Phospho (pT573)
2185-1
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young menJ Physiol 588 (2010) 3119-3130Burd NA, Holwerda AM, Selby KC, et al
S100 beta (C-term)
2017-1
Ocular perivascular epithelioid cell tumor: report of 2 cases with distinct clinical presentationsHum Pathol 41 (2010) 768-772Furusato E, Cameron JD, Newsom RW, et alIHC
S100 beta (C-term)
2017-1
Astrocyte activation and memory impairment in the repetitive febrile seizures modelEpilepsy Res. 86 (2009) 209-220Yang L, Li F, Zhang H, et alWB, IHC
S100 beta (C-term)
2017-1
Protective effects of naloxone in two-hit seizure modelEpilepsia 51 (2010) 344-353Yang L, Li F, Ge W, et alWB
Serum amyloid P-component (N-term)
1793-1
A serum amyloid P-binding hydrogel speeds healing of partial thickness wounds in pigsWound Rep Reg 17 (2009) 397–404Gomer RH, Pilling D, Kauvar LM, et alWB
SGK
1617-1
Subcellular location of serum- and glucocorticoid-induced kinase-1 in renal and mammary epithelial cellsAm J Physiol Cell Physiol 292 (2007) C1971–C1981Cordas E, Na´ray-Fejes-To´th A, and Fejes-To´th GWB
SHP-1
1606-1
CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19-mediated adhesion of B cells in a PI3K-dependent mannerJ. Leukoc. Biol. 83 (2009) 205 - 218Lobo EO, Zhang ZF, Shively JEWB
SHP-1
1606-1
Pivotal Advance: CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19-mediated adhesion of B cells in a PI3K-dependent mannerJ. Leukoc. Biol. 86 (2009) 205 - 218Lobo EO, Zhang ZF, Shively JEWB
SHP-1
1606-1
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Inhibits Proximal TCR Signaling by Targeting ZAP-70The Journal of Immunology 180 (2008) 6085–6093Chen ZG, Chen LF, Qiao S, et alIP
SHP-2 Phospho (pY542)
2184-1
The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cellsExp Cell Res. 315 (2009 ) 2343-2357Zhan Y, Counelis GJ, O'Rourke DMWB
Sir2/SIRT1
1104-1
Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotypeCardiovasc Res 85 (2010) 514-519Gracia-Sancho J, Villarreal G Jr, Zhang Y, et alWB
Sir2/SIRT1
1104-1
Balance between SIRT1 and DBC1 expression is lost in breast cancerCancer Sci 101 (2010) 1738-1744Sung JY, Kim R, Kim JE, et alWB, IHC
Sir2/SIRT1
1104-1
The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer GrowthPLoS ONE 3 (2008) :e2020Firestein R, Blander G, Michan S, et alIHC, ICC
Smad1
1649-1
Axotomy-induced Smad1 Activation Promotes Axonal Growth in Adult Sensory NeuronsJ Neurosci 29 (2009) 7116-7123Zou H, Ho C, Wong K, et alWB, ICC
Smad1
1649-1
Axotomy-Induced Smad1 Activation Promotes Axonal Growth in Adult Sensory NeuronsJ. Neurosci. 29 (2009) 7116 - 7123Zou HY, Ho C, Wong K, et al
Smad1
1649-1
Bone Morphogenetic Protein (BMP) Type II Receptor Is Required for BMP-mediated Growth Arrest and Differentiation in Pulmonary Artery Smooth Muscle CellsThe Journal of Biological Chemistry 283 (2008) 3877-3888Yu PB, Deng DY, Beppu H, et alWB, IP
Smad1
1649-1
BMP type I receptor inhibition reduces heterotopic ossificationNature Medicine 14 (2008) 1363-1369Yu PB, Deng DY, Lai CS, et alWB
Smad3
1735-1
Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and InvasivenessCancer Res 69 (2009) 735-740Jin CY, Yang YA, Anver MR, et alWB
Smad3
1735-1
Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signalingBiochem Pharmacol. 78 (2009) 301-314Szuster-Ciesielska A, Plewka K, Daniluk J, et alWB
Smad3
1735-1
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transitionJ. Biol. Chem. 283 (2008) 33437 - 33446Thuault S, Tan EJ, Peinado H, et alWB
Smad3
1735-1
Myostatin Inhibition Enhances the Effects of Exercise on Performance and Metabolic Outcomes in Aged MiceJ Gerontol A Biol Sci Med Sci 64A (2009) 940 - 948LeBrasseur NK, Schelhorn TM, Bernardo BL, et alWB
Smad3 Phospho (pS423/425)
1880-1
Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signalingBiochem Pharmacol. 78 (2009) 301-314Szuster-Ciesielska A, Plewka K, Daniluk J, et alWB
Smad3 Phospho (pS423/425)
1880-1
Transforming Growth Factor β1 Induces αvβ3 Integrin Expression in Human Lung Fibroblasts via αβ3 Integrin-, c-Src-, and p38 MAPK-dependent PathwayJ. Biol. Chem. 283 (2008) 12898 - 12908Pechkovsky DV, Scaffidi AK, Hackett TL, et alWB
Smad3 Phospho (pS423/425)
1880-1
Drosophila Mmp2 Regulates the Matrix Molecule Faulty Attraction (Frac) to Promote Motor Axon Targeting in DrosophilaJ Neurosci 31 (2011) 5335-5347Miller CM, Liu N, Page-McCaw A, et al
Smad3 Phospho (pS423/425)
1880-1
In vivo manipulation of heparan sulfate structure and its effect on Drosophila developmentGlycobiology 21 (2011) 607-618Kamimura K, Maeda N, Nakato H
Smad3 Phospho (pS423/425)
1880-1
Divergent Transforming Growth Factor-β Signaling in Hepatic Stellate Cells after Liver Injury: Functional Effects on ECE-1 RegulationAm. J. Pathol. 173 (2008) 716 - 727Khimji AK, Shao R, Rockey DCWB, ICC
Smad3 Phospho (pS423/425)
1880-1
Human Lung Parenchyma but not Proximal Bronchi Produces Fibroblasts with Enhanced TGF Signaling and SMA ExpressionAm J Respir Cell Mol Biol (2010) 641 - 651Pechkovsky DV, Hackett TL, An SS, et al
Smad3 Phospho (pS423/425)
1880-1
Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motilityNat Cell Biol. 11 (2009) 1287-1296Giampieri S, Manning C, Hooper S, et alIHC
Smad3 Phospho (pS423/425)
1880-1
Myostatin Inhibition Enhances the Effects of Exercise on Performance and Metabolic Outcomes in Aged MiceJ Gerontol A Biol Sci Med Sci 64A (2009) 940 - 948LeBrasseur NK, Schelhorn TM, Bernardo BL, et alWB
Smad3 Phospho (pS423/425)
1880-1
Smad3 Protein Levels Are Modulated by Ras Activity and during the Cell Cycle to Dictate Transforming Growth Factor-β ResponsesJ Biol Chem 285 (2010) 6489-6497Daly AC, Vizán P, Hill CS
Smad3 Phospho (pS423/425)
1880-1
Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and functionFASEB J 24 (2010) 4433-4442Murphy KT, Koopman R, Naim T, et al
Smad3 Phospho (pS423/425)
1880-1
Expression, purification, and functional characterization of recombinant PTD-SARAActa Biochim Biophys Sin (Shanghai) 43 (2011) 110-117Huang C, Du R, Zhang P, et al
Smad3 Phospho (pS423/425)
1880-1
Peripheral mural cell recruitment requires cell-autonomous heparan sulfateBlood 114 (2009) 915 -924Stenzel D, Nye E, Nisancioglu M, et al
Smad3 Phospho (pS423/425)
1880-1
Antibody-Directed Myostatin Inhibition Improves Diaphragm Pathology in Young but not Adult Dystrophic mdx MiceAm J Pathol 176 (2010) 2425-2434Murphy KT, Ryall JG, Snell SM, et al
Smad3 Phospho (pS423/425)
1880-1
In vivo manipulation of heparan sulfate structure and its effect on Drosophila developmentGlycobiology 21 (2011) 607-618Kamimura K, Maeda N, Nakato H
Smad3 Phospho (pS423/425)
1880-1
ATM/ATR and SMAD3 Pathways Contribute to 3-Indole-induced G1 Arrest in Cancer Cells and Xenograft ModelsAnticancer Res 31 (2011) 203-208Huang SM, Lu KT, Wang YC
Smad4
1676-1
The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formationDev Biol 335 (2009) 305-316Rajagopal R, Huang J, Dattilo LK, et alIHC
Smad5
1682-1
Bone Morphogenetic Protein (BMP) Type II Receptor Is Required for BMP-mediated Growth Arrest and Differentiation in Pulmonary Artery Smooth Muscle CellsThe Journal of Biological Chemistry 283 (2008) 3877-3888Yu PB, Deng DY, Beppu H, et alWB, IP
Smad5
1682-1
Cancer-Associated Transforming Growth Factor β Type II Receptor Gene Mutant Causes Activation of Bone Morphogenic Protein-Smads and Invasive PhenotypeCancer Res. 68 (2008) 1656-1666Bharathy S, Xie W, Yingling JM, et alWB
Smad7 Antibody (C-term)
T1688
Human Lung Parenchyma but not Proximal Bronchi Produces Fibroblasts with Enhanced TGF Signaling and SMA ExpressionAm J Respir Cell Mol Biol (2010) 641 - 651Pechkovsky DV, Hackett TL, An SS, et al
Somatostatin receptor type 2
3582-1
Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylationMol Endocrinol.Pöll F, Lehmann D, et alWB, IHC
Somatostatin receptor type 2
3582-1
Structural determinants of agonist-selective signaling at the sst(2A) somatostatin receptorMol EndocrinolNagel F, Doll C, et alWB
Somatostatin receptor type 3
6687-1
Reassessment of sst(3) Somatostatin Receptor Expression in Human Normal and Neoplastic Tissues Using the Novel Rabbit Monoclonal Antibody UMB-5NeuroendocrinologyLupp A, Nagel F, Doll C, Röcken C, Evert M, Mawrin C, Saeger W, Schulz S.
Sonic Hedgehog Protein / SHH (C-Product)
1843-1
The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during DevelopmentCurr Biol 19 (2009) 1320-1326Endoh-Yamagami S, Evangelista M, Wilson D, et alICC
SR-B1 Scavenge Receptor
1971-1
The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteumReproduction 139 (2010) 163-176Bogan RL, Hennebold JDWB
Src
1587-1
Expression of Src and FAK in Hepatocellular Carcinoma and the Effect of Src Inhibitors on Hepatocellular Carcinoma In VitroDig Dis Sci. 54 (2009) 1465-1474Lau GM, Lau GM, Yu GL, et alIHC
Stat-3
2281-1
Material hepatic growth response to pregnancy in the mouseExp Biol Med (Maywood). (2011) 236(11):1322-32 Guoli Dai, Juan J Bustamante, et al
Stat-3
1122-1
Manipulating transgenes using a chromosome vectorNucleic Acids Res 37 (2009) e44Ikeno M, Suzuki N, Hasegawa Y, et alICC
Stat-3
1122-1
Programmed Hyperphagia Due to Reduced Anorexigenic Mechanisms in Intrauterine Growth-Restricted OffspringReproductive Sciences 14 (2007) 329-337Desai M, Gayle D, Han G, et alWB
Stat-3 Phospho (pS727)
1121-1
STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cellsExperimental cellreseach 314 (2008) 377-386Onishi A, Chen QM, Humtsoe JO, et alWB
Stat-3 Phospho (pS727)
1121-1
Clinical Trial of Doxycycline for Matrix Metalloproteinase-9 Inhibition in Patients With an Abdominal Aneurysm Doxycycline Selectively Depletes Aortic Wall Neutrophils and Cytotoxic T CellsCirculation 119 (2009) 2209-2216Lindeman JHN, Abdul-Hussien H, Bockel JH, et alWB
Stat-3 Phospho (pY705)
2236-1
Programmed Hyperphagia Due to Reduced Anorexigenic Mechanisms in Intrauterine Growth-Restricted OffspringReproductive Sciences 14 (2007) 329-337Desai M, Gayle D, Han G, et alWB
Stat-5 alpha (C-term)
1289-1
Hyperactivated STAT3 in ALK–positive diffuse large B-cell lymphoma with clathrin-ALK fusionHuman Pathology 40 (2009) 75-82Momose S, Tamaru JI, Kishi H, et alIHC
Stat-5 alpha (C-term)
1289-1
Priming of peripheral monocytes with prolactin (PRL) sensitizes IFN- -mediated indoleamine 2,3-dioxygenase (IDO) expression without affecting IFN-γ signalingJournal of Reproductive Immunology 77 (2008) 117–125Kawaguchi R, Shimokawa T, Umehara N, et alWB
Stat-5 alpha (C-term)
1289-1
Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitorsBioorg Med Chem Lett 19 (2009) 6524-6528Ioannidis S, Lamb ML, Davies AM, et alWB
Stat-5 alpha (C-term)
1289-1
Hyperactivated STAT3 in ALK–positive diffuse large B-cell lymphoma with clathrin-ALK fusionHuman Pathology 40 (2009) 75–82Momose S, Tamaru JI, Kishi H, et alICC
Stat-5 Phospho (pY694)
1208-1
Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathwayLeukemia 22 (2008) 138–146Zhou J, Pan M, Xie Z, et alIHC
Stat-5 Phospho (pY694)
1208-1
HIV-1 determinants of thrombocytopenia at the stage of CD34+ progenitor cell differentiation in vivo lie in the viral envelope gp120 V3 loop regionVirology 401 (2010) 131-136Zhang M, Evans S, Yuan J, et alWB
Stat-5 Phospho (pY694)
1208-1
Anchoring of FLT3 in the endoplasmic reticulum alters signaling qualityBlood 113 (2009) 3568 - 3576Schmidt-Arras D, Böhmer SA, Koch S, et al
Stat-5 Phospho (pY694)
1208-1
Different STAT-3 and STAT-5 phosphorylation discriminates among Ph-negative chronic yeloproliferative diseases and is independent of the V617F JAK-2 mutationBlood 110 (2007) 354-359Teofili L, Martini M, Cenci T, et alIHC
Stat-5 Phospho (pY694)
1208-1
Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasmsBr J Haematol 147 (2009) 495-506Grimwade LF, Happerfield L, Tristram C, et alICC
Stat-5 Phospho (pY694)
1208-1
HIV-1 determinants of thrombocytopenia at the stage of CD34+ progenitor cell differentiation in vivo lie in the viral envelope gp120 V3 loop regionVirology 401 (2010) 131-136Zhang M, Evans S, Yuan J, et alWB
Stat-5 Phospho (pY694)
1208-1
Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 SignalingJ Biol Chem 286 (2011) 10918-10929Arora D, Stopp S, Böhmer SA, et al
Stat-5 Phospho (pY694)
1208-1
PTP1B Suppresses Prolactin Activation of Stat5 in Breast Cancer CellsAm J Pathol 177 (2010) 2971-2983ohnson KJ, Peck AR, Liu C, et al
Stat-5 Phospho (pY694)
1208-1
Phosphorylated STAT5 Represents a New Possible Prognostic Marker in Hodgkin LymphomaAm J Clin Pathol 129 (2008) 472 - 477Martini M, Hohaus S, Petrucci G, et al
Stat-5 Phospho (pY694)
1208-1
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study GroupBlood 115 (2010) 1006 - 1017Hertzberg L, Vendramini E, Ganmore I, et al
Stat-5 Phospho (pY694)
1208-1
Targeted Expression of GLI1 in the Mammary Gland Disrupts Pregnancy-induced Maturation and Causes Lactation FailureThe Journal of Biological Chemistry 282 (2007) 36090–36101Fiaschi M, Rozell B, Bergstrom A, et alIP
Stat-5 Phospho (pY694)
1208-1
Prolactin Inhibits BCL6 Expression in Breast Cancer through a Stat5a-Dependent MechanismCancer Res 70 (2010) 1711-1721Tran TH, Utama FE, Lin J, et alIHC
Stat-5 Phospho (pY694)
1208-1
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down’s syndromeThe Lance 372 (2008) 1484-1492Bercovich D, Ganmore I, Scott LM, et alWB
Synaptophysin
1485-1
Is TrpM5 a reliable marker for chemosensory cells? Multiple types of microvillous cells in the main olfactory epithelium of miceBMC Neuroscience 2008 9:115Hansen A, Finger TE
Synaptophysin
1485-1
Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1Proc Natl Acad Sci U S A 108 (2011) 319-324Smith ME, Cimica V, Chinni S, et al
Synaptophysin
1485-1
An antibody panel for immunohistochemical analysis of the retina in Davidson’s-fixed, paraffin-embedded eyes of ratsExperimental and Toxicologic Pathology 61 (2009) 91-100McKay JS, Steele SJ, Ahmed G, et alIHC
Synaptophysin
1485-1
Chronic Interleukin-1 Expression in Mouse Brain Leads to Leukocyte Infiltration and Neutrophil-Independent Blood–Brain Barrier Permeability without Overt NeurodegenerationThe Journal of Neuroscience 27 (2007 ) 9301–9309Shaftel SS, Carlson TJ,Olschowka JA, et alIHC
Synip
1668-1
Crosstalk between PTEN/Akt2 and TGFβ signaling involving EGF receptor down-regulation during the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis modelCancer Sci 100 (2009) 813–820Taniai E, Kawai M, Dewa Y, et alIHC
Synip
1668-1
Synip phosphorylation is required for insulin-stimulated Glut4 translocationBiochemical and Biophysical Research Communications 356 (2007) 102–106Okada S, Ohshima K, Uehara Y, et alIP
Tau
1178-1
Hyperphosphorylation and Aggregation of Tau in Laforin-deficient Mice, an Animal Model for Lafora DiseaseJ. Biol. Chem. 284 (2009) 22657 - 22663Puri R, Suzuki T, Yamakawa K, et alWB, IHC
Tau
2368-1
Effect of carbamylated erythropoietin on major histocompatibility complex expression and neural differentiation of human neural stem cellsJ Neuroimmunol 221 (2010) 15-24Fu ZQ, Shao QL, Shen JL, et alWB, ICC
TC10
1556-1
An essential role of Cdc42-like GTPases in mitosis of HeLa cellsFEBS Letters 580 (2006) 3375–3380Yasudaa S, Taniguchia H, Oceguera-Yanez F, et alICC
TCF-4
2114-1
Curcumin suppresses PPARδ expression and related genes in HT-29 cellsWorld J Gastroenterol 15 (2009) 1346-1352Wang JB, Qi LL, Zheng SD, et alWB
Thiophosphate Ester (WB version)
2686-1
Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3Sci Signal. (2011) 4(196):rs11Carlson SM, Chouinard CR, et al
Thiophosphate Ester (WB version)
2686-1
Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replicationGenes Dev 24 (2010) 2627-2639huluunbaatar U, Roller R, Feldman ME, et al
Thiophosphate Ester (WB version)
2686-1
Use of a semisynthetic epitope to probe histidine kinase activity and regulationAnal Biochem 397 (2010) 139-143Carlson HK, Plate L, Price MS, et alWB
Topoisomerase II alpha
1826-1
Topoisomerase II alpha as a universal tumor antigen: antitumor immunity in murine tumor models and H-2Kb-restricted T cell epitopeCancer Immunol Immunother 59 (2010) 747-757Park JS, Kim HS, Park MY, et alWB
Topoisomerase II alpha
1826-1
Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicityCarcinogenesis 30 (2009) 711-719Adler M, Müller K, Rached E, et alIHC
TRAF6
1660-1
Smac Mimetic Compounds Potentiate Interleukin-1β-mediated Cell DeathJ Biol Chem 285 (2010) 40612-40623Cheung HH, Beug ST, St Jean M, et al
TRAF6
1660-1
TRAF6 inhibits Th17 differentiation and TGF-β–mediated suppression of IL-2Blood 115 (2010) 4750-4757Cejas PJ, Walsh MC, Pearce EL, et al
Trk B Phospho (pY817)
2149-1
Status Epilepticus Induces a TrkB to p75 Neurotrophin Receptor Switch and Increases Brain-derived Neurotrophic Factor Interaction With p75 Neurotrophin Receptro: An Initial Event in Neuronal Injury InductionNeuroscience 154 (2008) 978–993N.Unsain, N.Nunez, A.Anastasia, et alWB
Trk B Phospho (pY817)
2149-1
BDNF Overexpression in the Forebrain Rescues Huntington's Disease Phenotypes in YAC128 MiceJ Neurosci 30 (2010) 14708-14718Xie Y, Hayden MR, Xu B
TSC1/Hamartin
1744-1
Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanismsHuman Molecular Genetics 17 (2008) 2006–2017Pymar LS, Platt FM, Askham JM, et alIHC
TSC1/Hamartin
1744-1
Spectrum of Phosphatidylinositol 3-Kinase Pathway Gene Alterations in Bladder CancerClin. Cancer Res. 15 (2009) 6008 - 6017Platt FM, Hurst CD, Taylor CF, et al
TSC2 / Tuberin Phospho (pS939)
1823-1
The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibitionOncogene 27 (2008) 6690-6697Shiono M, Kobayashi Y, Takahashi R, et alWB
TSC2/Tuberin (C-term)
1613-1
PTEN Deficiency Is Fully Penetrant for Prostate Adenocarcinoma in C57BL/6 Mice via mTOR-Dependent GrowthAm J Pathol 174 (2009) 1869-1879Blando J, Portis M, Benavides F, et alWB
TSC2/Tuberin (C-term)
1613-1
Toponomic analysis of functional interactions of the ubiquitin ligase PAM (Protein Associated with Myc) during spinal nociceptive processingMol. Cell. Proteomics 7 (2008) 2475 - 2485Pierre S, Maeurer C, Coste O, et al
TSC2/Tuberin (C-term)
1613-1
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROSProc Natl Acad Sci U S A 107 (2010) 4153-4158Alexander A, Cai SL, Kim J, et alWB
TSC2/Tuberin (C-term)
1613-1
Carboxy Terminal Tail of Polycystin-1 Regulates Localization of TSC2 to Repress mTORPLoS One 5 (2010) e9239Dere R, Wilson PD, Sandford RN, et alWB
TTF1
2044-1
Patterning of ventral telencephalon requires positive function of Gli transcription factorsDev Biol. 334 (2009) 264-275Yu W, Wang Y, McDonnell K, et alIHC
TTF1
2044-1
Dorsal Radial Glial Cells Have the Potential to Generate Cortical Interneurons in Human But Not in Mouse BrainJ Neurosci 31 (2011) 2413-2420Yu X, Zecevic N
TTF1
2044-1
Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapyProc Natl Acad Sci U S A 107 (2010) 20786-10791Doles J, Oliver TG, Cameron ER, et al
UBC9
2426-1
Identification of the non-structural influenza A viral protein NS1A as a bona fide target of the Small Ubiquitin-like MOdifier by the use of dicistronic expression constructsJ Virol Methods 163 (2010) 498–504Pal S, Rosas JM, Rosas-Acosta GWB
Ubiquitin
1646-1
Serotonergic dystrophy induced by excess serotoninMol Cell Neurosci 44 (2010) 297-306Daubert EA, Heffron DS, Mandell JW, et alIHC
Ubiquitin
1646-1
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on BorealinMol. Biol. Cell 20 (2009) 410 - 418Klein UR, Haindl M, Nigg EA, et alWB
Ubiquitin
1646-1
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradationJ. Clin. Invest. 119 (2009) 650–660Xiong H, Wang DL,Chen LN, et alWB
Vav
1746-1
Cooperative interactions at the SLP-76 complex are critical for actin polymerizationEMBO J 29 (2010) 2315-2328Barda-Saad M, Shirasu N, Pauker MH, et alIP
Vav2
1993-1
The Epidermal Growth Factor Receptor Mediates Tumor Necrosis Factor α--induced Activation of the ERK/GEF-H1/RhoA Pathway in Tubular EpitheliumJ Biol Chem 286 (2011) 9268-9279Kakiashvili E, Dan Q, Vandermeer M, et al
VEGF
1909-1
Curcumin suppresses PPARδ expression and related genes in HT-29 cellsWorld J Gastroenterol 15 (2009) 1346-1352Wang JB, Qi LL, Zheng SD, et alWB
VEGFR-1
1303-1
Soluble-Flt-1 Gene Therapy Ameliorates Albuminuria, but Accelerates Tubulointerstitial Injury in Diabetic MiceAm J Physiol Renal Physiol (2009)Kosugi T, Nakayama T, Li Q, et al
VEGFR-1
1303-1
Immunohistochemical expression of vascular endothelial growth factor A (VEGF), and its receptors (VEGFR1, 2) in normal and pathologic conditions of the human thymusAnn Anat 190 (2008) 238-245Cimpean AM, Raica M, Encicab S, et alIHC
VEGFR-1
1303-1
VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor GrowthCancer Res 71 (2011) 1474-1485Frank NY, Schatton T, Kim S, et al
VEGFR-1
1303-1
Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic miceAm J Physiol Renal Physiol 298 (2010) F609-F616Kosugi T, Nakayama T, Li Q, et al
VEGFR-1
1303-1
VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/- ) miceAm J Physiol Cell Physiol 293 (2007) C419-C428Amura CR, Brodsky KS, Groff R, et alWB
VEGFR-1
1303-1
A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivoNeuro Oncol 12 (2010) 580-594Yu L, Baxter PA, Voicu H, et alIHC
VEGFR-1
1303-1
The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathyLaboratory Investigation 88 (2008) 949–961Sato W, Kosugi T, Zhang L, et alWB, IHC
VEGFR-1
1303-1
Environmental Enrichment Counteracts Alzheimer’s Neurovascular Dysfunction in TgCRND8 MiceBrain Pathology 18 (2008) 32–39Herring A, Yasin H, Ambree O, et alIHC (4203-1), WB (1303-1)
Vimentin
4211-1
Matrix Metalloproteinase (MMP)-9, but Not MMP-2, Is Involved in the Development and Progression of C Protein-Induced Myocarditis and Subsequent Dilated CardiomyopathyJ. Immunol. 183 (2009) 4773 - 4781Matsumoto Y, Park IK, Kohyama K
Vimentin
4211-1
Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transitionFASEB J. 2010Mendez MG, Kojima SI, Goldman RDICC
VLA alpha 4
2101-1
Well Plate–Coupled Microfluidic Devices Designed for Facile Image-Based Cell Adhesion and Transmigration AssaysJ Biomol Screen 15 (2010) 102-106Conant CG, Schwartz MA, Ionescu-Zanetti C
YAP65
2060-1
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration programGenes & Dev 24 (2010) 2383-2388Cai J, Zhang N, Zheng Y,
YBOX1 / YB-1
2397-1
Foxo3a Suppression of Urothelial Cancer Invasiveness through Twist1, Y-Box–Binding Protein 1, and E-Cadherin RegulationClin Cancer Res 16 (2010) 5654-5663Shiota M, Song Y, Yokomizo A, et al