RabMAbs against Cleavage Specific Epitopes
Protein cleavage and proteolysis play major roles in diverse biological processes including:
- Normal protein processing and maturation
- Regulation of protein activity
- Protein localization to different cellular compartments
- Regulation of intracellular protein levels
Site-specific cleavage often results in protein fragments that possess distinct functional properties. The study of protein cleavage is greatly enhanced by cleavage specific antibodies that offer a simple and sensitive way to detect and quantify the cleaved fragments.
Rabbits have a unique immune system which allows them to develop antibodies that recognize subtle changes in epitopes such as those created upon protein cleavage. The high specificity and affinity of Epitomics RabMAbs allow unequivocal resolution of parental and cleaved protein fragments in Western blot, FACS, and IHC applications.
Anti-Poly (ADP-ribose) polymerase (PARP)
Anti-Caspase-3 Antibody
