Calretinin (CALB2) antibody 
RabMAb®
Cat.#: 2624-1
Rabbit Monoclonal Antibody
Swiss Prot: P22676
Mol Weight: 29kDa
Price: $260
Availability: Ship next business day
Description
Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to the calbindin family. It is mainly found in neuronal tissue, highly expressed in auditory neurons. It has been implicated as a calcium buffer, calcium sensor, and regulator of apoptosis (1). Calretinin is considered a specific marker of mesothelial cells; it is the only marker that has can distinguish between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas (2). It is widely used in a panel of markers for distinguishing mesothelioma from adenocarcinoma. Along with calretinin, the panel includes E-cadherin, CEA, and cytokeratin 5/6 (3).
Recommended Applications
WB, IHC, ICC, FC
Applications and Recommended Dilution Factors
WB: 1:1,000
IHC: 1:100 - 250
ICC: 1:100 - 250
FC: 1:100
Species Reactivity *
Human, Mouse, Rat
*For Mouse, this antibody is recommended for WB only
Rat cross reactivity tested by western blot only
Products Data
 |  |  |
| Western blot analysis on (A) Fetal Brain (B) Mouse brain and (C) Rat brain lysates using anti-Calretinin RabMAb (cat. #2624-1). | Immunonohistochemical analysis of paraffin-embedded human brain tissue using anti-Calretinin RabMAb (cat. #2624-1). | Immunonohistochemical analysis of paraffin-embedded human mesothelioma tissue using anti-Calretinin RabMAb (cat. #2624-1). |
Specificity
A synthetic peptide corresponding to residues in human Calretinin was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Alternative Names
CALB2 antibody, CAB29 antibody, CAL2 antibody, CR antibody, Calretinin antibody, 29 kDa calbindin antibody
Description References
1. Plattelli A et al. J Endocl 29(6):394-396, 2003. 2. Ordonez NG et al. Hum Pathol. 35(6):697-710, 2004. 3. Ordonez NG et al. Hum Pathol. 30(3):313-23. 1999.
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