Calretinin (CALB2) antibody 
RabMAb®
Cat.#: 4205-1
Rabbit Monoclonal Antibody
Swiss Prot: P22676
Mol Weight: 31.5kDa
Price: $205*
Availability: Ship next business day
Description
Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to the calbindin family. It is mainly found in neuronal tissue, highly expressed in auditory neurons. It has been implicated as a calcium buffer, calcium sensor, and regulator of apoptosis (1). Calretinin is considered a specific marker of mesothelial cells; it is the only marker that has can distinguish between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas (2). It is widely used in a panel of markers for distinguishing mesothelioma from adenocarcinoma. Along with calretinin, the panel includes E-cadherin, CEA, and cytokeratin 5/6 (3).
Recommended Applications
IHC
Applications and Recommended Dilution Factors
IHC: 1:100-1:200
Species Reactivity *
Human, Mouse, Rat
*Cross reactivity determined by western blot only.
Products Data
 |
| A. Immunohistochemical staining of paraffin-embedded Human mesothelioma stained with anti- Calretinin RabMAb (Cat. #4205-1) |
Specificity
Recombinant full length mouse calretinin protein.
Storage Condition and Buffer
Store at 2-8° C. Tissue culture supernatant with 0.1% sodium azide and 0.05% BSA. Stable for 12 months from the date of receipt.
Alternative Names
CALB2 antibody, CAB29 antibody, CAL2 antibody, CR antibody, Calretinin antibody, 29 kDa calbindin antibody
Description References
1. Plattelli A et al. J Endocl 29(6):394-396, 2003.
2. Ordonez NG et al. Hum Pathol. 35(6):697-710, 2004.
3. Ordonez NG et al. Hum Pathol. 30(3):313-23. 1999.
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