Filamin 1 antibody
Cat.#: S2806Rabbit Polyclonal Antibody
Swiss Prot: P21333
Mol Weight: 280.78kDa
Price: $289*
Availability: Ship 4-5 business days
Description
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
Species Reactivity *
Human
*Other species have not been tested
Products Data
 |
| Sample (30 ug of whole cell lysate) A: H1299 B: Hep G2 5% SDS PAGE diluted at 1:1000 |
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1769 and 2068 of Human FLNA
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
FLNA antibody, ABP-280 antibody, ABPX antibody, CVD1 antibody, DKFZp434P031 antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FMD antibody, MNS antibody, NHBP antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody, Filamin-A antibody, Alpha-filamin antibody, Endothelial actin-binding protein antibody, Filamin-1 antibody, Non-muscle filamin antibody
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