E3 ubiquitin-protein ligase CBL antibody
Cat.#: S1926Rabbit Polyclonal Antibody
Swiss Prot: P22681
Mol Weight: 99.65kDa
Price: $289*
Availability: Ship 4-5 business days
Description
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq]
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
Species Reactivity *
Human
*Other species have not been tested
Products Data
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| Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE diluted at 1:1000 |
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 661 and 863 of E3 ubiquitin-protein ligase CBL
Storage Condition and Buffer
1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
CBL antibody, C-CBL antibody, CBL2 antibody, RNF55 antibody, E3 ubiquitin-protein ligase CBL antibody, Casitas B-lineage lymphoma proto-oncogene antibody, Proto-oncogene c-Cbl antibody, RING finger protein 55 antibody, Signal transduction protein CBL antibody
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