PU.1 antibody
Cat.#: S1878Rabbit Polyclonal Antibody
Swiss Prot: P17947
Mol Weight: 31.09kDa
Price: $289*
Availability: Ship 4-5 business days
Description
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
IHC: 1:100-500
Species Reactivity *
Human
*Other species have not been tested
Products Data
 |  |
| Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE diluted at 1:1000 | Immunohistochemical analysis of paraffin-embedded NCI-N87 xenograft, using SPI1 antibody at 1:100 dilution. |
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 122 of Human SPI1
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
SPI1 antibody, OF antibody, PU.1 antibody, SFPI1 antibody, SPI-1 antibody, SPI-A antibody, Transcription factor PU.1 antibody, 31 kDa-transforming protein antibody
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