S6K antibody
Cat.#: S1049Rabbit Polyclonal Antibody
Swiss Prot: P23443
Mol Weight: 59.15kDa
Price: $289*
Availability: Ship 4-5 business days
Description
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq]
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
Species Reactivity *
Human
*Other species have not been tested
Products Data
 |
| Sample(30 ug whole cell lysate) A:293T 7.5% SDS PAGE diluted at 1:500 |
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 259 and 525 of Human RPS6KB1
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
RPS6KB1 antibody, PS6K antibody, S6K antibody, S6K1 antibody, STK14A antibody, p70(S6K)-alpha antibody, p70-S6K antibody, p70-alpha antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, Serine/threonine-protein kinase 14A antibody, p70 ribosomal S6 kinase alpha antibody
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