P27 Kip1 antibody
Cat.#: S0773Rabbit Polyclonal Antibody
Swiss Prot: P46527
Mol Weight: 22.08kDa
Price: $289*
Availability: Ship 4-5 business days
Description
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq]
Recommended Applications
WB, ICC
Applications and Recommended Dilution Factors
WB: 1:500-1:3000,IF:1:100-1:200
ICC: 1:100-1:200
Species Reactivity *
Human
*Other species have not been tested
Products Data
 |  |
| Sample (30 ug of whole cell lysate) A:NIH-3T3 12% SDS PAGE diluted at 1:1000 | Sample(30 ug of whole cell lysate) A:A431 12% SDS PAGE diluted at 1:200 |
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 55 and 195 of P27 Kip1
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
CDKN1B antibody, CDKN4 antibody, KIP1 antibody, MEN1B antibody, MEN4 antibody, P27KIP1 antibody, Cyclin-dependent kinase inhibitor 1B antibody, Cyclin-dependent kinase inhibitor p27 antibody, p27Kip1 antibody
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