Cbl Phospho (pS669) (CBL) antibody 
RabMAb®
Cat.#: 3411-1
Rabbit Monoclonal Antibody
Swiss Prot: P22681
Mol Weight: 120kDa
Price: $285*
Availability: Ship next business day
Description
Cbl was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:1,000-10,000
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis
Products Data
 |
| Western blot analysis on HeLa cell lysates using anti-Phospho-Cbl (pS669) RabMAb (cat. #3411-1). Cells were either (A) untreated (B) treated with pervanadate. |
Specificity
A phospho specific peptide corresponding to residues surrounding Serine 669 of human Cbl was used as an immunogen. This antibody only detects Cbl phosphorylated at Serine 669.
Storage Condition and Buffer
Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Alternative Names
CBL antibody, C-CBL antibody, CBL2 antibody, RNF55 antibody, E3 ubiquitin-protein ligase CBL antibody, Casitas B-lineage lymphoma proto-oncogene antibody, Proto-oncogene c-Cbl antibody, RING finger protein 55 antibody, Signal transduction protein CBL antibody
Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
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