p120 Catenin Phospho (pY96) (CTNND1) antibody RabMAb®

Cat.#: 2503-1
Abcam ID: ab75772

Rabbit Monoclonal Antibody

---

Download datasheet [PDF]|Similar Products|Related Products

Bulk and Custom formulation available Email request

---

Description

Catenins are proteins that are linked to the cytoplasmic domain of transmembrane cadherins. p120 Catenin is one member of this Armadillo gene family of junctional plaque proteins (1-3). The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Recently it became clear that some catenins also mediate nuclear signaling (1). p120 Catenin is implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.

Recommended Applications

WB, ICC

Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250

Species Reactivity *

Human

*Cross reactivity determined by western blot only.

---

Products Data

A.Western blot analysis on A431 cell lysates using anti-Phospho-p120 Catenin (pY96) RabMAb (cat. #2503-1). Cells were either (A) untreated (B) treated with pervanadate

---

Specificity

A phospho-specific peptide corresponding to residues surrounding Tyrosine 96 of human p120 Catenin was used as an immunogen. The antibody only detects p120 Catenin phosphorylated on Tyrosine 96.

Storage Condition and Buffer

Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Alternative Names

CTNND1 antibody, CAS antibody, CTNND antibody, P120CAS antibody, P120CTN antibody, p120 antibody, p120(CAS) antibody, p120(CTN) antibody, Catenin delta-1 antibody, p120(cas) antibody

Description References

1. Keirsebilck A., et al. Genomics 50(2): 129-146, 1998
2. Aho S., et al. J Cell Sci. 115:1391-1402, 2002
3. van Hengel J., et al. Proc Natl Acad Sci U S A. 96:7980-7985, 1999

Similar Products

Product Name	Catalog #
p120 Catenin RabMAb®	1506-1
p120 Catenin Phospho (pY228) RabMAb®	1205-1
p120 Catenin Phospho (pY291) RabMAb®	2270-1
p120 Catenin Phospho (pT310) RabMAb®	2542-1
p120 Catenin Phospho (pT916) RabMAb®	2611-1
p120 Catenin Phospho (pS268) RabMAb®	2572-1
p120 Catenin RabMAb®	2806-1
p120 Catenin DyLight® 488 RabMAb®	4578-1
p120 Catenin DyLight® 594 RabMAb®	4579-1

Related Products

Product Name	Catalog #
Goat Anti-Rabbit IgG (H+L) HRP	3053-1
Goat Anti-Rabbit IgG polymerized HRP	3051-1
Cell Lysis Buffer	3500-1
Goat Anti-Rabbit IgG HRP Antibody	3056-1