A synthetic peptide corresponding to residues in N-terminus of human p70 S6 kinase was used as immunogen. This antibody detects both alpha I and alpha II isoforms.

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

RPS6KB1, STK14A, Ribosomal protein S6 kinase beta-1, 70 kDa ribosomal protein S6 kinase 1;p70 S6 kinase alpha

1. Pearson, R.B. and G. Thomas. Regulation of p70s6k/p85s6k and its role in the cell cycle. Prog Cell Cycle Res. 1: 21
2. Pullen, N. and G. Thomas. The modular phosphorylation and activation of p70s6k. FEBS Lett. 410: 78
3. Dufner, A. and G. Thomas. Ribosomal S6 kinase signaling and the control of translation. Exp Cell Res. 253: 100
4. Le, X.F., et al. Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis. Oncogene 22: 484

1. Thuault S, Tan EJ, Peinado H, et al, HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition ,J. Biol. Chem. 283 (2008) 33437 - 33446
[Application: WB ]
2. Schroeder JT, Chichester KL, Bieneman AP, Human Basophils Secrete IL-3: Evidence of Autocrine Priming for Phenotypic and Functional Responses in Allergic Disease ,The Journal of Immunology 182 (2009) 2432-2438
[Application: ]
3. Khawam K, Giron-Michel J, Gu Y, et al, Human Renal Cancer Cells Express a Novel Membrane-Bound Interleukin-15 that Induces, in Response to the Soluble Interleukin-15 Receptor α Chain, Epithelial-to-Mesenchymal Transition ,Cancer Res 69 (2009) 1561-1569
[Application: WB ]
4. Nery FC, Zeng J, Niland BP, et al, TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton ,J Cell Sci 121 (2008) 3476-3486
[Application: WB ]
5. Kim WY, Chang DJ, Hennessy B, et al, A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy ,Cancer Prev Res 1 (2008) 577-587
[Application: WB ]
6. Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, et al, An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer ,Cancer Res 68 (2008) 6084-6091
[Application: RPPA ]
7. Maehama T, Tanaka M, Nishina H, et al, RalA functions as an indispensable signal mediator for nutrient sensing system ,J. Biol. Chem. 283 (2008) 35053 - 35059
[Application: WB ]