Background: OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage.

Specificity: This OGG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316~345 amino acids from the C-terminal region of human OGG1.

Storage Condition and Buffer: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Recommended Dilutions:
WB: 1:100~500
ELISA: 1:1,000

Background References:
Wozniak,K., et.al., J. Biomed. Biotechnol. 2009, 827562 (2009)