Background: Fukutin is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. It is thought to be a glycosyltransferase and could play a role in brain development. Defects in Fukutin are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X) (1).

Specificity: A synthetic peptide corresponding to residues in human Fukutin was used as an immunogen.

Storage Condition and Buffer: Store at -20° C. Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Recommended Dilutions:
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:250 - 500

Background References:
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.

*Species cross-reactivity is based on WB analysis.