Rabbit Monoclonal Antibody | Product Data Sheet
|Quantity: 100ul||Lot #: Please refer to vial|
|Clone ID: EPR7913||Molecular Wt.: 54 kDa|
|Species Cross-reactivity* +Human+Mouse+Rat||UniProt ID: O75072|
Background: Fukutin is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. It is thought to be a glycosyltransferase and could play a role in brain development. Defects in Fukutin are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X) (1).
Specificity: A synthetic peptide corresponding to residues in human Fukutin was used as an immunogen.
Storage Condition and Buffer: Store at -20° C. Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:250 - 500
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
*Species cross-reactivity is based on WB analysis.
Fig 1. Western blot analysis on (A) HeLa, (B) A549, (C) fetal heart, and (D) BxPC-3 lysates using anti-Fukutin RabMAb (cat. #5982-1).
Fig 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Fukutin RabMAb (cat. #5982-1).