Background: Claudin-2 belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. Claudin-2 is expressed in the intestine (1).

Specificity: A synthetic peptide corresponding to residues at the C-terminus of human Claudin-2 was used as an immunogen.

Storage Condition and Buffer: Store at -20° C. Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Recommended Dilutions:
WB: 1:1,000 - 10,000

Background References:
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.

*Species cross-reactivity is based on WB analysis.