Rabbit Monoclonal Antibody | Product Data Sheet
|Quantity: 100ul||Lot #: Please refer to vial|
|Clone ID: EPR8200||Molecular Wt.: 38 kDa|
|Species Cross-reactivity* +Human+Mouse+Rat||UniProt ID: P02724|
Background: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. It is important for the function of SLC4A1 and required for the high activity of SLC4A1. Glycophorin A may be involved in the translocation of SLC4A1 to the plasma membrane. Is a receptor for the influenza virus and Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans (1).
Specificity: A synthetic peptide corresponding to residues in human Glycophorin A was used as an immunogen.
Storage Condition and Buffer: Store at -20° C. Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:10 - 100
1. The UniProt Consortium Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).
*Species cross-reactivity is based on WB analysis.
Fig 1. Western blot analysis on fetal liver lysate using anti-Glycophorin A RabMAb (cat. #5874-1).
Fig 2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Glycophorin A RabMAb (cat. #5874-1).