Fra-1 DyLight® 488 Rabbit Monoclonal
Rabbit Monoclonal Antibody | Product Data Sheet
|Quantity: 100UL||Lot #: Please refer to vial|
|Clone ID: EP4711||Molecular Wt.: 40 kDa|
|Species Cross-reactivity n/dHumann/dMousen/dRat||UniProt ID: P15407|
Background: The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. Fra-1, known as Fos-related Antigen 1 or FOSL1, is a leucine zipper protein that can dimerize with JUN family proteins, thereby forming the transcription factor complex AP-1. As such, Fra-1 has been implicated as regulators of cell proliferation, differentiation, and transformation (1).
Specificity: A synthetic peptide corresponding to residues in human Fra-1 was used as an immunogen.
Storage Condition and Buffer: Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt.
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
Fig 1. Immunofluorescent staining of A431 cells using anti-Fra-1 antibody conjugated with Dylight 488 (green, Cat# 4603-1) and Dapi (blue).