Clone ID: SP16
Antibody Type: Rabbit Monoclonal IgG
Catalog#: 4207-1
Size: 100ul
Price: $ 205
Recommended Applications: IHC
Species Reactivity: Human
Mol. Weight: 32 kDa
UniProt ID: P01732
Alternative names: T-lymphocyte differentiation antigen T8/Leu-2, CD8a antigen
Description: The T cell coreceptor CD8 is a cell-surface glycoprotein expressed either as a disulfide-linked homodimer of two CD8alpha monomers, or a heterodimer of CD8alpha and CD8beta. These receptors interact with ligands, such as major histocompatibility complex (MHC) class I, on the outside of the cell, with proteins inside the cell, such as the tyrosine kinase p56lck, and possibly with proteins on the same cell-surface (1). CD8 plays an important role in T cell development in the thymus and T cell activation in the periphery (2). Specificity: A synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule.
Recommended Dilutions:
IHC: 1:100
Protocols for using Epitomics Rabbit Monoclonal Antibodies
|
|
| A. Immunohistochemical staining of paraffin-embedded Human tonsil stained with anti-CD8 RabMAb (Cat. #4207-1) |
|
References:
| 1. |
Devine L, et al. Immunol Res, 19(2-3):201-10, 1999. |
| 2. |
Wong, JS, et al. J Immunol 171:867-874, 2003 |
Orders:
877-772-2622 (US and Canada)
650-443-2276 (Domestic and International)
orders@epitomics.com
Technical Support: support@epitomics.com
*Determined species reactivity – for other species not listed cross reactivity
may be possible but not tested. |
