Clone ID: EPR1040Y
Antibody Type: Rabbit Monoclonal IgG
Catalog#: 2288-1
Size: 100
Price: $ 250
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| A. Western blot analysis on U937 cell lysate using anti-Integrin beta-1 Rabbit Monoclonal (cat. # 2288-1), at dilution 1:500. |
B. Immunohistochemical analysis of paraffin-embedded human brain (endothelial cells) using anti-Integrin beta 1 RabMAb |
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| C. Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma using anti-CD29 RabMAb (cat# 2288-1). |
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Recommended Applications: WB, IHC, ICC
Species Reactivity: Human
Mol. Weight: 140 - 150 kDa
UniProt ID: P05556
Alternative names: Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, CD29 antigen
Description: Integrin beta-1 (ITGB1, CD29, VLA-beta) is the beta subunit found in the integrin families, forming a heterodimer integrin receptor through non-covalent bonding with various integrin alpha subunits. Integrin heterodimer containing Integrin beta-1 binds to various cell surface and extracellular proteins (CD49a-f, CD51) to mediate cell to cell and cell to matrix adhesion (1). Integrin beta-1 plays a critical role in the cell adhesion and recognition in embryogenesis, hemostasis, immune response, tissue repair, metastatic diffusion of tumor cells and development (2, 3, 4). Specificity: A synthetic peptide corresponding to the residues in human Integrin beta-1 (CD29) was used as immunogen.
Recommended Dilutions:
WB: 1:500
IHC: 1:250
ICC: 1:50 - 100
Protocols for using Epitomics Rabbit Monoclonal Antibodies
Description References:
| 1. |
SF Schlossman et al. Oxford 1612-1613, 1995. |
| 2. |
H Li et al. Blood 102(10):3652-3657, 2003. |
| 3. |
C Cayrol et al Oncogene, 25:4421 |
Orders:
877-772-2622 (US and Canada)
650-583-6688 (Domestic and International)
orders@epitomics.com
Technical Support: support@epitomics.com
Product MSDS: view page or download PDF
*Determined species reactivity – for other species not listed cross reactivity
may be possible but not tested. |
