Clone ID: EP1363Y
Antibody Type: Rabbit Monoclonal IgG
Catalog#: 2098-1
Size: 100ul
Price: $ 215
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| A. Western blot analysis on 5 ng mouse MDC recombinant protein using anti-ABCD-1 RabMAb (cat. # 2098-1), dilution 1:500. |
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Recommended Applications: WB
Species Reactivity: Mouse
Mol. Weight: 8 kDa
UniProt ID: O88430
Alternative names: Small-inducible cytokine A22, CC chemokine ABCD-1, Activated B and dendritic cell-derived
Description: Chemokines are a large family of small secreted proteins that regulate migration of white blood cells. Based on the arrangement of the first two of the four conserved cysteine residues, chemokines are classified into four subfamilies, CXC, CC, C and recently identified CX3C (1). The CC chemokines, in which the first 2 cysteines are adjacent, usually act on monocytes, T lymphocytes, and, in some cases, eosinophils, basophils, or mast cells. The CC subfamily proteins are 70 to 100 amino acids long, have 25 to 75% identity with each other, and include novel member of the CC chemokine subfamily, designated ABCD1 (SCYA22). The SCYA22 protein shares 28 to 34% identity with other CC chemokines and contains the characteristic 4-cysteine motif and 9 other highly conserved residues (2). The activated T cell-attracting CC chemokine CCL22 is expressed by stimulated B cells and mature dendritic cells (DC). Both identical and distinct proteins contribute to expression of CCL22 in DC and B cells (3). Specificity: A synthetic peptide corresponding to residues near the C-terminus of mouse ABCD-1 was used as an immunogen.
Recommended Dilutions:
WB: 1:250 - 500
Protocols for using Epitomics Rabbit Monoclonal Antibodies
References:
| 1. |
Nomiyama H, et al. Cytogenetics and Cell Genetics 81:10-11, 1998. |
| 2. |
Godiska R, et al. J Exp Med 185(9):1595-604, 1997. |
| 3. |
Ghadially H, et al. J Immunol 174(9):5620-9, 2005. |
Orders:
877-772-2622 (US and Canada)
650-443-2276 (Domestic and International)
orders@epitomics.com
Technical Support: support@epitomics.com
*Determined species reactivity – for other species not listed cross reactivity
may be possible but not tested. |
