Clone ID: EP1935Y
Antibody Type: Rabbit Monoclonal IgG
Catalog#: 2070-1
Size: 100ul
Price: $ 250
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| A.Western blot analysis on human liver lysate using anti-Aldh7a1 Rabbit Monoclonal (cat. # 2070-1), dilution 1:100,000. |
B. Immunohistochemical analysis of paraffin-embedded human liver using anti-Aldh7a1 RabMAb (cat. #2070-1).
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Recommended Applications: WB, IHC. ICC, IP
Species Reactivity: Human, Mouse
Mol. Weight: 55 kDa
UniProt ID: P49419
Alternative names: Alpha-AASA dehydrogenase, Delta1-piperideine-6-carboxylate dehydrogenease, P6c dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Antiquitin-1
Description: Antiquitin (Aldh7a1) is an evolutionarily conserved protein believed to play a role in the regulation of cellular turgor. Based on sequence analysis, this protein is classified as a member of the aldehyde dehydrogenase superfamily (1). Analysis of the amount of mRNA in various rat and human tissues indicates that the largest amounts are found in rat kidney and liver and in cultured human hepatoma cells. Only minimal amounts were detected in human peripheral blood leukocytes, rat lung, or cultured human fibroblasts (2). The plant homolog of ATQ1 is thought to be involved in regulating turgor pressure, a function that also would be essential for cells of the mammalian cochlea. Northern blots of 13 human fetal tissues show antiquitin to be highly expressed in cochlea, ovary, eye, heart, and kidney (3). Specificity: A synthetic peptide corresponding to residues near the C-terminus of human Aldh7a1 was used as an immunogen.
Recommended Dilutions:
WB: 1:50,000-100,000
IHC: 1:250-500
ICC: 1:250-500
IP: 1:30
Protocols for using Epitomics Rabbit Monoclonal Antibodies
Description References:
| 1. |
Tang WK, et al. FEBS Lett 516(1-3):183-6, 2002 |
| 2. |
Lee P, et al. Genomics 21(2):371-8, 1994 |
| 3. |
Skvorak AB, et al. Genomics 46(2):191-9, 1997 |
Orders:
877-772-2622 (US and Canada)
650-583-6688 (Domestic and International)
orders@epitomics.com
Technical Support: support@epitomics.com
Product MSDS: view page or download PDF
*Determined species reactivity – for other species not listed cross reactivity
may be possible but not tested. |
