The mitogen-activated protein kinase (MAPK) signaling pathways are involved in various cell functions, such as cell apoptosis, differentiation, migration and proliferation. MAPK signaling cascades are highly conserved and at least three MAPK signaling pathways have been characterized: extracellular signal-regulated kinase (ERK), Jun kinase (JNK) and p38 MAPK (1).
At Epitomics, we provide a wide range of high quality antibodies to MAP Kinase pathways (MAPK-ERK, MAPK-JNK, MAPK-p38). Using our patented Rabbit Monoclonal Antibody (RabMAb®) technology, we have developed a collection of high quality MAP Kinase pathway specific antibodies. Each RabMAb offers superior antigen recognition of the rabbit immune system and the specificity of a monoclonal antibody (2,3).
We validate every RabMAb in western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation and flow cytometry before release, so you can be assured of which assays will work.
Complete list of MAPK Kinase Pathways related Antibodies >>
For MAPK pathways, we have created interactive ePath pathway maps of MAPK-ERK, MAPK-JNK and MAPK-p38. All these pathways feature Epitomics Rabbit Monoclonal Antibodies (RabMAbs).
MAPK signal pathways in the regulation of cell proliferation in mammalian cells Cell Research (2002) 12, 9–18
2. A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models Yu Y, et al., [PLoS One. 2010 Feb 5;5(2):e9072]
3. Rabbit monoclonal antibody: potential application in cancer therapy Lifeng Feng, Xian Wang, and Hongchuan Jin [Am J Transl Res. 2011 May 15; 3(3): 269–274]