In Vitro Diagnostics
Size: 1ml, Format: Concentrate
CD23, a type II transmembrane glycoprotein, is a key molecule for Bcell activation and growth and functions as a receptor for IgE. CD23 antibody labels activated B cells expressing IgM/IgD and follicular dentritic cells. In tumors, CD23 antibody is helpful in identification of B-cell chronic lymphocytic leukemia (CLL), follicular dendritic cell tumors and mediastinal large B cell lymphoma. In addition, anti- CD23 is useful to differentiate CLL from mantle cell lymphoma which is CD23 negative.