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In Vitro Diagnostics

Monoclonal Rabbit anti-Human 

Cytokeratin 8Cat.#: AC-0007


Clone ID: EP17
Classification: IVD
Size: 1ml, Format: Concentrate

Description

Cytokeratin 8 (CK8) is an intermediate filament protein produced early in embryogenesis. It is the only type-II CK occurring in many simple epithelial in respiratory, gastrointestinal, male and female reproductive tract and thyroid. CK8 is often co-expressed with Cytokeratin 18. CK8/18 is the major keratin pair in simple-type epithelia, as found in the liver, pancreas, and intestine. CK8 is used to detect adenocarcinomas with simple epithelium origin. The difference in staining pattern is useful to distinguish duct (peripheral staining) from lobular (perinuclear staining) breast carcinoma.

Applications

IHC